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Inference of chromosome selection parameters and missegregation rate in cancer from DNA-sequencing data
Nature
Aneuploidy is frequently observed in cancers and has been linked to poor patient outcome. Analysis of aneuploidy in DNA-sequencing (DNA-seq) data...
19 hours ago
Bayesian updating for ground surface settlements of shield tunneling
Frontiers
Accurate prediction of ground surface settlements induced by shield construction is of great significance for ensuring the safety of shield construction.
1 month ago
Consequences of Lack of Parameterization Invariance of Non-informative Bayesian Analysis for Wildlife Management: Survival of San Joaquin Kit Fox and Declines in Amphibian Populations
Frontiers
Computational convenience has led to widespread use of Bayesian inference with vague or flat priors to analyze statistical models in ecology.
1 month ago
How Should We Quantify Uncertainty in Statistical Inference?
Frontiers
An inferential statement is any statement about the parameters, form of the underlying process or future outcomes. An inferential statement, that provides...
1 month ago
Evaluating Diagnostic Tests With Near-Perfect Specificity: Use of a Hui–Walter Approach When Designing a Trial of a DIVA Test for Bovine Tuberculosis
Frontiers
Active surveillance of rare infectious diseases requires diagnostic tests to have high specificity, otherwise the false positive results can outnumber the...
1 month ago
Automatic differentiation and the optimization of differential equation models in biology
Frontiers
A computational revolution unleashed the power of artificial neural networks. At the heart of that revolution is automatic differentiation, which calculates...
1 month ago
Inferring fruit infestation prevalence from a combination of pre-harvest monitoring and consignment sampling data
Nature
International trade in horticultural produce happens under phytosanitary inspection and production protocols. Fruit inspection typically involves the...
1 month ago
Reverse engineering morphogenesis through Bayesian optimization of physics-based models
Nature
Morphogenetic programs coordinate cell signaling and mechanical interactions to shape organs. In systems and synthetic biology, a key challenge is...
2 months ago
Global ranking of the sensitivity of interaction potential contributions within classical molecular dynamics force fields
Nature
Uncertainty quantification (UQ) is rapidly becoming a sine qua non for all forms of computational science out of which actionable outcomes are anticipated.
2 months ago
Spatial non-parametric Bayesian clustered coefficients - Scientific Reports
Nature
In the field of population health research, understanding the similarities between geographical areas and quantifying their shared effects on health...
3 months ago