2 days ago · This project will address the hypothesis that the creation of distinct tumor-like niches and crosstalk between cells residing within these niches up-regulates ...

6 days ago · Protein kinase dysregulation, implicated in various diseases via cell signaling pathways, can be therapeutically and experimentally managed through allosteric ...

4 days ago · We have discovered that extracellular-regulated MAP kinase (ERK1/2) activity adapts to both chronic alcohol drinking and abstinence, and that ERK1/2 ...

4 days ago · In this review, we discuss new insights into the pathophysiology of viral encephalitis, with a focus on myeloid cells and CD8+ T cells, which critically ...

7 days ago · Unlike the above-mentioned ROS-related cell death mechanisms, iron death involves a distinct regulatory pathway targeting LPO. Arachidonate lipoxygenase (ALOX), ...

7 days ago · In this study, we investigated the molecular mechanism underlying SLAC1 activation using a multidisciplinary approach that included protein sequence analysis, ...

2 hours ago · Apr. 30, 2024 — A new study has found that pancreatic cancer cells are different based on their location in the pancreas, providing new information about tumors ...