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Aug 27, 2024 · The CCND1 genes were found very close to the IGH locus in naive B cells and further away after maturation. In contrast, the CMYC alleles became localized ...
Aug 27, 2024 · ... Chromosome 11 - NC_000011.10 Genomic Context describing neighboring genes ... Molecular Biology Databases. Bgee database. CCND1 gene expression. BioGPS. BioGPS.
Aug 12, 2024 · CCND1 mutations were found predominantly in exon 1 (9 of 10 CCND1-mutated cases) (SI Appendix, Fig. S6) and were more frequent in SOX11-negative MCL [6/7 ...
Aug 11, 2024 · 53 CCND1 belongs to a family of highly conserved cell-cycle proteins that are frequently overexpressed in a variety of malignancies such as hepatocellular ...
Aug 15, 2024 · In line with this model, both BCL2 in DLBCL/FL and CCND1 in IGHV-mutated MCL showed clear evidence of SBS84 signature-mediated kataegis (ie, AID), a hallmark ...
Aug 6, 2024 · This gene is found in a cluster of related genes on chromosome 14 and is thought to be involved in limb development. Defects in this gene are a cause of ...
Aug 7, 2024 · ... CCND1, ERBB2, MYC and KLF5, and ... Most candidate SV target genes were annotated to the locations of drivers found in the small-scale mutation analysis.
6 days ago · Chromatin immunoprecipitation and CRISPR/Cas9 mutagenesis showed that STAT5B recruits METTL3 to gene promoters like CCND1, where METTL3 interacts with RPB1, ...
Aug 6, 2024 · Expressed in secondary oocyte, epithelial cell of pancreas, calcaneal tendon and 188 other cell types or tissues. Genes that share expression patterns with ...
Aug 12, 2024 · These three amplicons, located at 14q13.3, 5p15.33, and 8p11.21, contained between 5 and 11 known genes. We chose to pursue the 14q13.3 amplicon for further ...