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Jul 6, 2024 · Genotype imputation is widely used in genome-wide association studies (GWAS). However, both the genotyping chips and imputation reference panels are ...
Apr 20, 2024 · Genotype imputation is widely used in genome-wide association studies (GWAS). However, both the genotyping chips and imputation reference panels are ...
scholar.google.com › citations
Jan 15, 2024 · The imputation of unmeasured genotypes is essential in human genetic research, particularly in enhancing the power of genome-wide association studies and ...
The hazards of genotype imputation when mapping disease ...
genomebiology.biomedcentral.com › arti...
Jan 3, 2024 · Imputation is not a panacea for fine mapping, nor for meta-analysing multiple GWAS based on different arrays and different populations.
Jan 13, 2024 · Large-scale imputation reference panels are currently available and have contributed to efficient genome-wide association studies through genotype imputation.
Apr 20, 2024 · We propose a new method, two-stage imputation (TSIM), where cohorts are imputed separately, merged on intersecting high-quality variants, and imputed again.
Jul 25, 2024 · The aim of this study is to find out an optimal strategy for accurately imputing of LCWGS data and assess its effectiveness for genomic prediction (GP) and ...
Dec 27, 2023 · A flexible and accurate genotype imputation method for the next generation of genome-wide association studies. PLoS Genet. 5, e1000529 (2009). Article PubMed ...
Jul 6, 2024 · Genotype imputation is routinely used in well-studied species to buffer the impact in downstream analysis, and several algorithms are available to fill in ...
A cross-cohort transferable genotype imputation quality metric - PubMed
pubmed.ncbi.nlm.nih.gov › ...
May 2, 2024 · MagicalRsq-X shows superiority for post-imputation QC and benefits genetic studies by distinguishing well and poorly imputed lower-frequency variants.