Janeane Garofalo at an event for Portlandia (2011)

Janeane Garofalo and Owen Wilson in The Minus Man (1999)

Janeane Garofalo, Tony Goldwyn, and Giancarlo Esposito in Ash Tuesday (2003)

Uma Thurman, Janeane Garofalo, and Ben Chaplin in The Truth About Cats & Dogs (1996)

Janeane Garofalo in Nadine in Date Land (2005)

Janeane Garofalo, Forest Whitaker, Michael Kelly, Kirsten Vangsness, Beau Garrett, and Matt Ryan in Criminal Minds: Suspect Behavior (2011)

Hank Azaria, Janeane Garofalo, William H. Macy, Paul Reubens, Ben Stiller, Kel Mitchell, and Wes Studi in Mystery Men (1999)

Hank Azaria, Janeane Garofalo, and Geoffrey Rush in Mystery Men (1999)

Janeane Garofalo, Vince Vaughn, and Joaquin Phoenix in Clay Pigeons (1998)

Christina Ricci, Ben Affleck, Janeane Garofalo, Martha Plimpton, Casey Affleck, Courtney Love, Jay Mohr, Kate Hudson, Dave Chappelle, and Paul Rudd in 200 Cigarettes (1999)

Hank Azaria, Janeane Garofalo, William H. Macy, Paul Reubens, Ben Stiller, Kel Mitchell, Melinda Sue Gordon, Wes Studi, and Jeff Lunn in Mystery Men (1999)

Janeane Garofalo in Wet Hot American Summer: First Day of Camp (2015)

Janeane Garofalo and Christopher Meloni in Wet Hot American Summer: First Day of Camp (2015)

Janeane Garofalo, Josh Charles, Elizabeth Banks, Zak Orth, and Kevin Sussman in Wet Hot American Summer: First Day of Camp (2015)

Janeane Garofalo, Elizabeth Banks, Michael Ian Black, and Zak Orth in Wet Hot American Summer: First Day of Camp (2015)

Janeane Garofalo and Kevin Sussman in Wet Hot American Summer: First Day of Camp (2015)

Janeane Garofalo, Jason Schwartzman, and Kevin Sussman in Wet Hot American Summer: First Day of Camp (2015)

Janeane Garofalo, Jason Schwartzman, Michael Cera, and Kevin Sussman in Wet Hot American Summer: First Day of Camp (2015)

Janeane Garofalo, Jason Schwartzman, and Michael Cera in Wet Hot American Summer: First Day of Camp (2015)

Janeane Garofalo, Michael Cera, and Bruce Greenwood in Wet Hot American Summer: First Day of Camp (2015)

Janeane Garofalo and Michael Cera in Wet Hot American Summer: First Day of Camp (2015)

Janeane Garofalo, Michael Cera, and Kevin Sussman in Wet Hot American Summer: First Day of Camp (2015)

Janeane Garofalo, Jason Schwartzman, Michael Cera, and Bruce Greenwood in Wet Hot American Summer: First Day of Camp (2015)

Christina Ricci, Ben Affleck, Janeane Garofalo, Jay Mohr, Kate Hudson, and Paul Rudd in 200 Cigarettes (1999)

Christina Ricci, Ben Affleck, Janeane Garofalo, Casey Affleck, Courtney Love, Jay Mohr, Tori Spelling, Angela Featherstone, Kate Hudson, Dave Chappelle, and Paul Rudd in 200 Cigarettes (1999)

Mike Myers, Robert Englund, Janeane Garofalo, Virginia Madsen, Kristen Johnston, Tim Meadows, Alanna Ubach, Margaret Cho, Richard Kind, Ed Lauter, Michael Lerner, Wayne Rogers, Ryan Stiles, and Fred Willard in Nobody Knows Anything! (2003)

Janeane Garofalo, John Ritter, Nestor Carbonell, and Lauren Tom in Manhood (2003)