- 1995: Retired from acting and moved to British Columbia, Canada, to devote herself to writing and raising a family.
- Said that her worst film experience was working with Anthony Perkins and director Richard Franklin in Psycho II (1983). Her best film experience was working with director Norman Jewison and co-stars, Jane Fonda and Anne Bancroft in Agnes of God (1985). Interestingly, both films resulted in Tilly being nominated for several awards, including a Golden Globe and an Oscar.
- While older sister Jennifer Tilly has remained mum about the history of childhood sexual abuse in the family recently revealed by Meg (which included her stepfather and one of her mother's boyfriends), youngest sister Becky has corroborated her sister's revelations.
- Son, with Colin Firth, William Joseph Firth (b. 1990).
- Younger sister of actress Jennifer Tilly and Steve Tilly.
- Her first fiction novel was "Singing Songs" (1994; Dutton Books) based on memories of her own childhood. Her second novel "Gemma" (2006; Syren Book Company), is a graphic, disturbing tale about child sexual abuse, which has prompted her to recently reveal her own true-life sexual abuse as a youngster growing up.
- While filming One Dark Night (1982), she was incredibly uncomfortable in the actual mausoleum. Her reactions to her surroundings were often genuine. During the scenes where she was hysterical, she actually did throw herself into hysterics and it took her awhile after each take to calm herself down.
- Her father was of Chinese descent and her mother had Irish and Finnish ancestry.
- Was in consideration for the part of Mia Wallace in Pulp Fiction (1994) but Uma Thurman, who went on to receive a Best Supporting Actress Oscar nomination for her performance, was cast instead.
- Younger sister, Becky, is a post-impressionist painter.
- Was originally cast as Mozart's wife in Amadeus (1984), but had to leave after tearing a ligament in her leg during a soccer game with her children one day before her shooting started.
- Children from her marriage to Tim Zinnemann: Emily (b. 1984) and David (b. 1986).
- Abandoned acting after Journey (1995) in order to focus on her family and her writings. She didn't act again until Unvanquished (2010).
- In high school, everyone called Jennifer, Meg, and their younger sister Becky the Three Musketeers.
- Former daughter-in-law of Fred Zinnemann.
- Ex-sister-in-law of Sam Simon.
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