- Auditioned for the situation comedy That '70s Show (1998) at age 14. Though actors had to be at least 18 to get the role, she truthfully claimed she would be 18 on her birthday, not specifying which birthday, and won the role.
- Mila said that she was blind in one eye because of a condition called chronic iritis. She underwent surgery to correct the blindness. (January 2011)
- She and Laura Prepon were often filmed sitting down for their scenes on That '70s Show (1998) because Laura, at 5' 10", is six inches taller than Mila, at 5' 4". In other scenes, Mila wore platform shoes to give her four extra inches.
- She and her ex-boyfriend, actor Macaulay Culkin, were close friends with Michael Jackson and his family for many years until Jackson's death. Culkin is godfather of his children. Kunis attended a private funeral for Jackson on September 3, 2009, with Culkin.
- Mila and her family moved from Ukraine to Los Angeles, California when she was age seven. Her father, Mark, is a mechanical engineer. Her mother, Elvira, is a physics teacher. Her brother, Michael, is a biochemist.
- Had a body double for her nude scene in Friends with Benefits (2011).
- Is a self-confessed huge fan of the Star Trek franchise.
- She and Sarah Michelle Gellar have a special credit in every episode of Robot Chicken (2001).
- On July 7, 2011 she was invited, via YouTube, to the US Marine Corps Ball in Greenville, NC by Sgt. Scott Moore. At the time of the Internet invite, Moore was stationed in Musa Qala, Afghanistan with the 3rd Battalion, 2nd Marines. Her Friends with Benefits (2011) co-star, Justin Timberlake, came into contact with Sgt. Moore after seeing his video and then contacted Kunis about the invite. Kunis accepted the invite on July 12, 2011.
- Her first kiss was onscreen with Ashton Kutcher during That '70s Show (1998). She was really nervous. To help her own confidence, she perfumed herself and acted cool towards Ashton. Ashton did not know about this until three years later.
- Not long after her relationship with Macaulay Culkin ended, she admitted that Ashton Kutcher was her celebrity crush. During that time, Ashton was married to Demi Moore.
- On the television show Loveline (1996), she mentioned that when she was younger, she had serious migraines that were caused by an eye condition. She had to insert steroid injections straight into her eye.
- Was in a relationship with Macaulay Culkin (May 2002-December 2010).
- The nude pictures of her in Forgetting Sarah Marshall (2008) were not real, according to the film's director, Nicholas Stoller.
- Is a huge fan of the hard rock band Aerosmith.
- Learned how to use a gun while filming Max Payne (2008).
- Is a huge fan of the famed MMORPG World of Warcraft.
- Terrified of bugs so much that during her May 2004 appearance on Late Night with Conan O'Brien (1993), she ran offstage when the Bug Man appeared after her interview.
- Sister-in-law of Alexandra Blacker, who trained her for her role in Black Swan (2010).
- Attended the University of California, Los Angeles (UCLA) for a semester and then transferred to Loyola Marymount University (LMU) in Los Angeles, California before dropping out to continue her acting career.
- Despite having different last names, she and her husband, Ashton Kutcher, have consecutive IMDb profile numbers. Mila has nm0005109 and Ashton has nm0005110.
- Her name is pronounced MEE-luh koon-iss.
- Was one month pregnant with her son Dimitri when she completed filming Bad Moms (2016).
- At age nine, she started to take afterschool acting classes at the Beverly Hills Studios. At one of the Studios' public showcases, Mila was approached by entertainment manager Susan Curtis, who offered to make her a client.
- Returned to work 16 months after giving birth to her daughter Wyatt to begin filming Bad Moms (2016). Also returned to work five months after giving birth to her son Dimitri to begin filming A Bad Moms Christmas (2017).
- Auditioned for a role in the romantic comedy Knocked Up (2007).
- She and Macaulay Culkin were on vacation in Israel in 2006 when a war broke out between Israel and Hezbollah in Lebanon. They flew out of the country and back to the United States. Mila later stated that they were never in any danger from rocket fire.
- Counts Free Willy (1993) as the first movie that made her cry. This was also the very first movie she saw in the United States.
- Attended and graduated from Fairfax Senior High School in June 2001, with Fernanda Romero. However, she missed her senior prom because of a scheduling conflict.
- She describes her role as Jupiter Jones in Jupiter Ascending (2015) as unhappy with her job and life, but also lazy and with no aspirations to do anything about it until Caine Wise (Channing Tatum) finds her.
- Attended the San Diego Comic-Con in 2008, alongside director John Moore and Mark Wahlberg, to promote Max Payne (2008). She returned in 2009 to promote Extract (2009), The Book of Eli (2010) and Family Guy (1999).
- When she was younger, her best friend was Maria Osadchy, an Aries whom she met in second grade. Maria is Russian and helped Mila learn English and Ukrainian. In an interview, Mila had Maria with her and talked about how they spent the night together on the weekends.
- Has appeared with Seth Green on two situation comedies: That '70s Show (1998) and Family Guy (1999).
- Speaks English, Ukrainian and Russian fluently.
- Won the 2011 Guys Choice Award "Holy Grail of Hot" beating out Minka Kelly.
- She holds dual American and Ukrainian nationality and citizenship.
- Was the fifth highest paid actress of 2017 with $15.5 million.
- The shark-tooth necklace she wears as Rachel Jansen in Forgetting Sarah Marshall (2008) is designed by Pade Vavra Designs.
- Has played two characters named "Rachel": Rachael Newman in American Psycho II: All American Girl (2002) and Rachel Jansen in Forgetting Sarah Marshall (2008).
- Was on the Time 100, a list of the 100 most influential people in the world by Time magazine. (2022)
- She has Ashkenazi Jewish ancestry on both sides on her family.
- She was included in FHM UK's '100 Sexiest Women' in 2010 (#14), 2011 (#16), 2012 (#9), 2013 (#1) and 2014 (#9); FHM Australia's '100 Sexiest Women' in 2011 (#6); Stuff magazine's '102 Sexiest Women' in 2002 (#54); Maxim magazine's Hot 100 Women in 2001 (#62), 2003 (#79), 2006 (#47), 2008 (#81), 2009 (#5), 2010 (#22), 2011 (#5), 2012 (#3), 2013 (#4), 2014 (#9), 2015 (#11) and 2016 (#74); AskMen's Top 99 Women of 2011 (#2), 2012 (#13) and 2013 (#2); and was named Esquire magazine's "Sexiest Woman Alive" in 2012.
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