- Is the first stand-up comedian to perform on The Tonight Show with Conan O'Brien (2009).
- His father was a dentist, and Bill worked for him as a dental hygienist for some time.
- His brother Robert is a selectman and was briefly a candidate to fill Massachusetts' vacant seat in the US Senate after the death of Ted Kennedy (I) in 2009.
- Is a licensed helicopter pilot, his proudest accomplishment having been realized in 2015.
- He and his wife Nia welcomed their first child, a daughter, on January 20, 2017.
- Worked in a warehouse before becoming a comedian.
- Graduate of Emerson College in Boston, MA.
- Of Irish, French and German descent.
- Bill Burr quickly rose to fame after his infamous Philadelphia stand-up set that the Opie & Anthony show hosted. Since then he was known to be a "no-nonsense" comedian that frequently made fun of cancel culture and his "gingerness".
- Known as a huge sports fan.
- Supports the New England Patriots.
- Co-founded the All Things Comedy network and digital studio in 2012 with fellow comedian Al Madrigal.
- Mother is a nurse.
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