Julia Roberts, Shirley MacLaine, Kathy Bates, Patrick Dempsey, Hector Elizondo, Queen Latifah, Anne Hathaway, Jessica Alba, Jessica Biel, Jamie Foxx, Jennifer Garner, Ashton Kutcher, Bradley Cooper, Eric Dane, Topher Grace, George Lopez, Emma Roberts, Taylor Lautner, Bryce Robinson, and Taylor Swift in Valentine's Day (2010)

Julia Roberts, Shirley MacLaine, Patrick Dempsey, Hector Elizondo, Queen Latifah, Anne Hathaway, Jessica Alba, Jessica Biel, Jamie Foxx, Jennifer Garner, Ashton Kutcher, Bradley Cooper, Eric Dane, Topher Grace, George Lopez, Taylor Lautner, Bryce Robinson, and Taylor Swift in Valentine's Day (2010)

Patrick Dempsey, Katherine Heigl, Kate Walsh, Justin Chambers, Eric Dane, Sandra Oh, James Pickens Jr., Ellen Pompeo, Sara Ramirez, Isaiah Washington, Chandra Wilson, and T.R. Knight in Grey's Anatomy (2005)

Edward James Olmos and Eric Dane in One Fast Move (2024)

Eric Dane and KJ Apa in One Fast Move (2024)

Teri Polo and Eric Dane in The Ravine (2021)

Keri Russell, Eric Dane, and Andrew Kavovit in Married... with Children (1987)

Eric Dane in Married... with Children (1987)

Amanda Bearse, Eric Dane, and Andrew Kavovit in Married... with Children (1987)

Jessica Capshaw, Eric Dane, Chyler Leigh, Kevin McKidd, Sandra Oh, Ellen Pompeo, Sara Ramirez, and Chandra Wilson in Grey's Anatomy (2005)

Eric Dane and Marissa Neitling in The Last Ship (2014)

Eric Dane, Aaron Stanford, Omahyra, and Dania Ramirez in X-Men: The Last Stand (2006)

Eric Dane, Jocko Sims, and Kevin Michael Martin in The Last Ship (2014)

Adam Baldwin, Eric Dane, and Rhona Mitra in The Last Ship Prequel: Dr. Scott's Video Journal (2014)

Kathleen Robertson and Eric Dane in The Fixer (2015)

Adam Baldwin, Eric Dane, and Rhona Mitra in The Last Ship (2014)