- Great friends with Game of Thrones co-workers Lena Headey (Cersei) and Richard Madden (Robb Stark).
- Michelle Fairley has been nominated for an Olivier award for her role in Othello.
- Replaced Judy Davis as Margot Al-Harazi in 24: Live Another Day (2014).
- Had roles in 2 epic fantasy series playing the mother of a principal character: In Harry Potter and the Deathly Hallows: Part 1 (2010) as Hermione's mother, and in Game of Thrones (2011) as the mother of all the Stark children.
- Various sources show her date of birth was being as early as 1963, to as late as July, 1965. One source actually lists both 1963 and January 17, 1964.
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