- He and wife Lisa Picotte have guest-starred together on several series, including Highway to Heaven (1984) (playing boyfriend and girlfriend), as well as playing husband and wife in Wings (1990) and Step by Step (1991).
- He has two roles in common with Michael J. Fox: (1) Fox played Marty McFly in Back to the Future (1985), Back to the Future Part II (1989), Back to the Future Part III (1990) and Back to the Future: The Game (2010) while Kaufman played him in Back to the Future (1991) and (2) Fox played Stuart Little in Stuart Little (1999), Stuart Little 2 (2002) and Stuart Little 3: Call of the Wild (2005) while Kaufman played him in Stuart Little (2003).
- Has one daughter Grace Kaufman.
- Has one son, Henry Kaufman.
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