- She is the only Bond girl other than Eunice Gayson to appear in more than one film as the same character.
- Her parents both have mixed French and Alsatian German ancestry. Her father also has a small amount of Venezuelan (including Spanish and Basque) roots.
- As of 2016, has appeared in three films that were nominated for the Best Picture Oscar: Inglourious Basterds (2009), Midnight in Paris (2011) and The Grand Budapest Hotel (2014).
- She is the only actress that has played in both major spy-genre movie franchises: Mission Impossible (Mission: Impossible - Ghost Protocol (2011)) and James Bond (Spectre (2015)).
- In a relationship with André Meyer since 2013. They have a son together, George Meyer (born January 18, 2017).
- Granddaughter of Jérôme Seydoux, Chairman of Pathé, grandniece of Nicolas Seydoux, Chairman and CEO of Gaumont and daughter of Henri Seydoux, Founder, Chairman and CEO of Parrot.
- She is the only actress to play a main Bond girl and appear in two films as the same character in the franchise's history.
- Goddaughter of Christian Louboutin.
- Daughter of Henri Seydoux, a businessman, and Valérie Schlumberger, a former model and actress.
- Featured on W Magazine's portfolio on Best Performances of 2013, for her performance as "Emma" in Blue Is the Warmest Colour (2013).
- She was among the actresses considered for the role of Lisbeth Salander in The Girl with the Dragon Tattoo (2011) before Rooney Mara was cast.
- Wanted to be an opera singer and studied at the Conservatoire de Paris.
- Member of the 'Official Competition' jury at the 71st Cannes International Film Festival in 2018.
- Studied at the Actor's Studio in New York.
- The actresses who inspire her are Catherine Deneuve, Cate Blanchett, Gena Rowlands, Isabelle Huppert and Marion Cotillard.
- In 2022, Léa Seydoux received the title of Officier de la Légion d'Honneur by France's president Emmanuel Macron.
- She has five half siblings from both of her parents, 3 from her mother and two from her father.
- In July 2021, Seydoux tested positive for COVID-19 while filming Mia Hansen-Løve's One Fine Morning (2022), was asymptomatic and isolating at her Paris home. The diagnosis caused her to miss the 2021 Cannes Film Festival, where she had 4 movies premiering at the festival: The French Dispatch (2021), France (2021), The Story of My Wife (2021), and Deception (2021).
- Seydoux has expressed a preference for defining herself by the term "actor" rather than "actress", saying: "I really don't feel like an actress, I feel like an actor".
- Josh Brolin wrote a poem for her on the set of Dune: Part Two (2024).
- She is the great-niece of French businessman and film producer Michel Seydoux.
- On Vogue (UK) magazine's Best Dressed List (2013).
- Gave birth to her first child, George Meyer, at 32 years-old, the same age that her mother Valérie Schlumberger also gave birth to her last daughter, which is Léa.
- Léa Seydoux has been nominated at the César Awards five times. In 2009, for Christophe Honoré's La Belle Personne. In 2011, for Rebecca Zlotowski's Belle Épine. In 2013, for Benoît Jacquot's Les Adiex à la reine. In 2014, for Abdellatif Kechiche's La vie d'Adèle. In 2022, for Bruno Dumont's France.
- Appeared on the cover of Vanity Fair's 20th Hollywood Issue [March 2014].
- Has a country house in the province of Brittany, in the north-west of France, where she vacations.
- Was cast in Arnaud des Pallières's Captives (2023), but had to drop out due to scheduling conflicts with Denis Villeneuve's Dune: Part Two (2024).
- Wes Anderson wrote the role of Simone in The French Dispatch (2021) with Seydoux in mind.
- In 2020, Seydoux was included on Vogue's list of "The most beautiful French actresses of all time".
- Has an older sister from the same parents, Camille.
- Has been a Louis Vuitton ambassador since 2016.
- Mia Hansen-Løve wrote the script of One Fine Morning (2022) with Seydoux in mind for the role of Sandra.
- In March of 2022, Catherine Deneuve sent flowers and wrote a letter to congratulate Seydoux for her performance in The Story of My Wife (2021).
- Was described by Thierry Frémaux as "Brigitte Bardot, plus Juliette Binoche, plus Kate Moss, and sometimes all three at once.".
- Acclaimed french director Benoît Jacquot offered Seydoux two screenplays: Deep in the Woods (2010) and Farewell, My Queen (2012). She chose Farewell, My Queen (2012), which ended up earning her a third César Award nomination.
- Stepdaughter of Farida Khelfa.
- Bourgeoise part Noble.
- Stated her desire to work with directors Céline Sciamma, Jacques Audiard, Leos Carax, Éric Toledano and Olivier Nakache.
- The Royal Tenenbaums (2001) is her favorite Wes Anderson film.
- Seydoux said she "fell in love" with dutch actor Gijs Naber when she saw him dressed in character for the first time on the set of The Story of My Wife (2021).
- Was the face of Prada Candy from 2011 to 2014.
- Actress Florence Pugh stated in an interview for SensCritique in 2020 that she has a crush on Seydoux.
- Seydoux revealed that she visited the set of Dune: Part One (2021) in Budapest while she was shooting Ildikó Enyedi's The Story of My Wife (2021) in 2019. Years later, Denis Villeneuve offered her the role of Lady Margot Fenring in Dune: Part Two (2024).
- Considers Joachim Trier as a contemporary filmmaker with an unusual artistic vision.
- Considers Anna Karina as her favorite actress.
- Stated that Sister (2012) is one of the movies in her filmography that she is most proud of.
- Wes Anderson met Seydoux while filming Prada: Candy (2013). He was impressed by how fast she would understand his directions, even if he wasn't personally on the set, and shortly after offered her a small part in The Grand Budapest Hotel (2014).
- In 2018, Seydoux was invited to join the Academy of Motion Picture Arts and Sciences (AMPAS).
- Dropped out of two projects in 2023: Emmanuelle (2024) and The Shrouds (2024) due to personal reasons. In 2024, Seydoux said that she needed a break from acting to enjoy daily life.
- Director Bertrand Bonello said that Seydoux is the Catherine Deneuve of her generation.
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