- Speaks fluent English and Bulgarian. Also speaks some French.
- She was born in Bulgaria and speaks Bulgarian. For this reason Katherine, who was German in the books, became Bulgarian in the series.
- Is a very skilled ballet and jazz dancer and gymnast.
- Traveled to Kenya where she built a school with fellow Degrassi: The Next Generation (2001) co-stars through the non-profit organization, Free The Children. She also wore a top promoting the cause towards the end of her movie, The American Mall (2008).
- One of her hobbies is making jewelry. She plans on starting her own jewelry line in the future.
- Has competed internationally representing Canada in Aesthetic Group Gymnastics. In 2005 she joined both the Senior World Championships in Copenhagen, Denmark, and the Junior World Championships in Plzen, Czech Republic.
- Her favorite actresses are Meryl Streep and Rachel McAdams.
- Her father Konstantin Aleksandrov Dobrev is a computer specialist and her mother Mihaela Efiova Radeva is an artist.
- She's a huge fan of the "Harry Potter" series, by J.K. Rowling.
- Went into a general audition for Degrassi: The Next Generation (2001) and read for the role of Manny Santos but didn't get it. Later she was called back, read for the role of Mia Jones and got it.
- Is frequently compared, and is aware of bearing a resemblance, to Victoria Justice.
- Is six years younger than Olga Fonda, who played her daughter on The Vampire Diaries (2009).
- Some of her favorite films include Schindler's List (1993), The Notebook (2004), Juno (2007) and Knocked Up (2007).
- Her favorite television series are Orange Is the New Black (2013), Homeland (2011), Grey's Anatomy (2005), Friday Night Lights (2006) and House of Cards (2013).
- Wears glasses.
- Attended Wexford Collegiate, an arts school in Toronto. In 2007 she began her post-secondary studies at Ryerson University in Toronto, where she was majoring in Sociology.
- Enjoys playing "Rock Band" and engages in water sports including swimming, windsurfing, wake boarding and scuba diving. Nina also loves to travel and often visits Europe. Among her other activities are playing volleyball, soccer, horseback riding, snowboarding and rock climbing.
- Is a fan of the HBO television series True Blood (2008).
- Has an older brother named Alexander Konstantinov Dobrev.
- Has played a teenage mother on Degrassi: The Next Generation (2001) and played both a teenage mother and daughter of teenagers on The Vampire Diaries (2009).
- Named after her maternal grandmother Nikolina Constantine.
- Shared an apartment in Atlanta, GA, with Kayla Ewell.
- Ranked #53 on "Maxim" magazine's Hot 100 Women of 2014 list.
- Is a huge fan of Chicago (2002). She derived inspiration from the song "Cell Block Tango" for her performance of "Survivor" in The American Mall (2008).
- She is very creative in making jewelry and also she used to design her own jewelry.
- Studied acting at Armstrong Acting Studios in Toronto, Ontario, Canada.
- Would like to open a yoga studio one day.
- Has two pets--a dog and a cat named Miss Linx.
- Second child and only daughter of Konstantin Dobrev and Michaela Dobrev (nee Radeva).
- Lists child rights advocate Craig Kielburger and Meryl Streep among the people she admires.
- Best friends with Julianne Hough.
- Ranked #44 in the 2011 "FHM" Australia list of "100 Sexiest Women in the World".
- Enjoys competing in athletic competitions.
- She took acting classes at Armstrong's acting studios in Toronto.
- In a relationship with snowboarder Shaun White [2023].
- Is a huge fan of the Netflix series, House of Cards (2013).
- In October 2024, Dobrev announces her engagement to three time Olympic gold medalist snowboarder, skateboarder and musician Shaun White. After four year of dating.
- Attendee at the 2008 Toronto International Film Festival (TIFF).
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