"El Chavo del Ocho" has been my favorite Spanish-speaking show. It was like a ritual to me seeing this hilarious show every single day. It's about a Vecindad ("neighborhood") in which an orphan, called Chavo (Mexican equivalent word for lad or kid), lives. He is eight years old (played by a then fortyish actor) and has no parent. He is always starved and lacks of proper hygiene. He shares his live with the other dwellers of the vecindad.
Part of the success of the show is that it's full of colorful characters played by gifted and talented actors. My favorite is "Don Ramón" played by late Mexican actor Ramón Valdez. "Kiko" was also hilarious. The rest of the characters are good, though. If you understand Spanish, you will love this show.