The whites of Whip's eyes change from extremely bloodshot to normal in the first scene of him in the hospital after the crash.
When the plane is out of control and flying upside down, the view from the house on the ground shows that the plane is only about 100ft above the ground, however the view from the cockpit window suggests the plane is flying about 2000ft above the ground.
Katerina wears two different types of underwear in the same hotel scene.
When Whip looks at his iPhone, the time on the locked screen says 1:16 - 1:17, but when the phone is unlocked it says 8:52.
When the answering machine at Whip's father's house is heard after Whip throws a bottle at a picture, the automated message is shorter. "Flying lessons and plane rides" and "thank you" are omitted from the message.
The NTSB investigation portrayed in the movie includes recovered data from the Cockpit Voice Recorder. US law requires Cockpit Voice Recorders to include at least 30 minutes of audio data from both pilots and Air Traffic Control radio transmissions. Since the plane crashed in less than 30 minutes, the audio from the CVR should have included Evans and Margaret's conversation about Whip sleeping on the job. This would have raised serious questions about Whip's behavior aside from his alcohol and drug usage. However, nothing about this is mentioned at any point during the NTSB hearing.
During the moments just before the crash, the First Officer extinguishes the engine fires by pulling so called T-handles. When a T-handle is pulled it activates the fire extinguisher, but also it cuts off the fuel flow to deprive the fire of it. In the movie the engines are seen operating after the T-handles are pulled.
Hugh Lang states that they take "blood, hair and skin samples" for toxicology tests. Drugs are not detectable in skin samples. He should have said "blood, hair and urine samples," which is what they actually take.
The NTSB will not use "Act of God" as a reason for an aircraft accident. If the cause are not known with certainty they will state it as such, and list all possible causes. Also in this case the direct cause was a mechanical failure with underlying systematic failures as a root cause, obviating the need to refer to unknown causes or "Act of God" all together.
The NTSB does not do toxicology tests on flight attendants. Additionally, if Whip had the drug problem shown in the movie, the FAA mandated random drug screenings of pilots would have caught him before it got to the point it did in the movie.
Unless Whip handled the vodka bottles with gloves the whole time from obtaining them to disposing of them, there would be fingerprints easily available for the NTSB investigation.
However, it is clearly stated by Hugh that there were no fingerprints on the bottle. It is probable that they were smudge and a clean print was unable to be pulled.
It is unexplained how the connecting door in the hotel room next to Whip's moves by itself to produce the "knocking" noise.
Moved by wind through open window, indicated by swaying curtains.
When Harling and Whip are in Harlings car after leaving the Hospital you can clearly see that the Gearshift is in the park position and the ignition switch is in off position even though they are traveling down the road.
When Whip looks at his iPhone, the date on the locked screen says October 20th, but his calendar on the home screen says the 8th.
While Whip is in his hospital bed, the NTSB agent sets down a recorder. The light on the recorder is "blinking" red, which means it is paused in recording mode. If it were recording, the red light would be "solid". It does turn solid at the end when the agent motions to turn the recorder off -- which is really "record".
In the footage of the crash shown on the hospital TV, the aircraft is smaller than usual.
During the takeoff scene, when Evans says, "You're way too fast for this rough air," the numerical airspeed increases from 315 to 319 kts. However, as this happens, the green arrow next to the meter indicates that the airspeed is decreasing.
The smoke from Harling's cigarette should have triggered the smoke detectors in Whip's hotel room.
When the aircraft is flying inverted and the audience is shown the view from the flight deck, it is presumably meant to show the pilot's perspective. However, the view shows the ground on the bottom and the sky on the top. This is incorrect - a pilot flying inverted would see the sky on the bottom and ground on top. However, the location of the windshield wipers does correctly show as inverted - the wiper is shown against the sky.
Prior to his hearing, Whip was able to obtain alcohol from a minibar in the hotel room next to his via an unlocked door. It is assumed that hotels always keep any door that connects rooms locked unless it is a suite.
When Whip wakes in the hospital, he is told that he is in a hospital in south Atlanta. Later, he looks out the window at the Concourse Buildings (The "King" and "Queen"), which are north of Atlanta.
We see the inverted plane flying over Nicole's apartment when paramedics are removing her in her Bankhead neighborhood apartment. Based on the location on Bankhead versus Hartsfield airport, the plane would have never been flying anywhere near Nicole's neighborhood as it is father NW of the airport which is SE of town. If the plane had the ability to make it as far as Bankhead, it certainly would have already been able to land at ATL-Hartsfield which would have been closer on the flight-path from MCO-Orlando.
Nicole mentions that her apartment is in Bankhead, which is on the west side of Atlanta, but when the skyline is visible from her apartment, it is east of downtown.
When Whip and Hugh Lang visit the crash site and Lang describes the left wing hitting the ground, a subsequent discussion between the two men implies that the left wing hit the rear fuselage and drove the left engine nacelle into the fuselage. It is implied that this is what killed the four passengers. However, the view of the crashed plane clearly shows the left engine nacelle intact and attached to the outside of the fuselage.
During the NTSB hearing, Ellen Block refers to either the cockpit voice recorder or flight data recorder as the "cockpit data recorder."
Captain Whitaker asks his co-pilot to switch controls to manual and calls the handle to do so "red". The handle shown is yellow.
When Whip asks Nicole where she lives she says "the Georgian Terraces," but her room is in the Georgian Gardens. The Georgian Terrace (singular) is a venerable hotel where actors often stay when they're filming in Atlanta.
When Whip is in the bar and orders and orange juice and a double Stoli, the bartender only serves him a single. The standard US shot is 1.5oz (47ml) and takes three seconds to pour with a standard shot pour, which is exactly how long it took the bartender to pour. It's also evident that there is only a single shot in the glass.