Writer and director Wes Anderson hosted a competition for someone to be a member of the voice cast for this film. The only requirement was that they donated ten dollars or more to the Film Foundation, a non-profit founded by Martin Scorsese, which specializes in the preservation and restoration of film around the world.
The hair of the dogs is made out of alpaca wool.
The title "Isle of Dogs" is a play on words. Said quickly and fluidly it sounds like "I love dogs." However, the play on words only works in English and loses that meaning in the Japanese pronunciation of the kanji, "Inu ga shima."
The movie was influenced by the work of Akira Kurosawa and Rankin-Bass stop-motion Christmas specials.
As of 2018, since his debut film Bottle Rocket (1996), director Wes Anderson had used one cinematographer for his live-action films (Robert D. Yeoman), and one for his stop-motion films (Tristan Oliver).
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