Entry
Name
indoleamine 2,3-dioxygenase;
IDO (ambiguous);
tryptophan pyrrolase (ambiguous);
D-tryptophan:oxygen 2,3-oxidoreductase (decyclizing)
Class
Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of two atoms of oxygen
BRITE hierarchy
Sysname
D-tryptophan:oxygen 2,3-oxidoreductase (ring-opening)
Reaction(IUBMB)
(1) D-tryptophan + O2 = N-formyl-D-kynurenine [RN:
R07362 ];
(2) L-tryptophan + O2 = N-formyl-L-kynurenine [RN:
R00678 ]
Reaction(KEGG)
Substrate
Product
N-formyl-D-kynurenine [CPD:
C15605 ];
N-formyl-L-kynurenine [CPD:
C02700 ]
Comment
A protohemoprotein. Requires ascorbic acid and methylene blue for activity. This enzyme has broader substrate specificity than EC
1.13.11.11 , tryptophan 2,3-dioxygenase [1]. It is induced in response to pathological conditions and host-defense mechanisms and its distribution in mammals is not confined to the liver [2]. While the enzyme is more active with D-tryptophan than L-tryptophan, its only known function to date is in the metabolism of L-tryptophan [2,6]. Superoxide radicals can replace O2 as oxygen donor [4,7].
History
EC 1.13.11.52 created 2006
Pathway
Orthology
K00463 indoleamine 2,3-dioxygenase
Genes
HSA : 169355(IDO2) 3620(IDO1)
PTR : 464134(IDO1) 472744(IDO2)
PPS : 100969906(IDO2) 100970596(IDO1)
GGO : 101131712(IDO1) 101134018(IDO2)
PON : 100435160(IDO2) 100436652(IDO1)
PPYG : 129042836(IDO2) 129042837(IDO1)
NLE : 100580631(IDO1) 100580956(IDO2)
HMH : 116461652(IDO1) 116461868(IDO2)
SSYN : 129491826(IDO1) 129491827(IDO2)
MCC : 574370(IDO1) 707424(IDO2)
MCF : 102126825(IDO1) 102129002(IDO2)
MTHB : 126961208 126961209
MNI : 105476547(IDO1) 105476549(IDO2)
CSAB : 103215667(IDO2) 103215668(IDO1)
CATY : 105590814(IDO1) 105590816(IDO2)
PANU : 101010384(IDO1) 101010746(IDO2)
TGE : 112630102(IDO1) 112630460(IDO2)
MLEU : 105535001(IDO2) 105535011(IDO1)
RRO : 104655209(IDO2) 104655211(IDO1)
RBB : 108537679(IDO2) 108537681(IDO1)
TFN : 117095206(IDO1) 117095225(IDO2)
PTEH : 111544106(IDO2) 111544107(IDO1)
CANG : 105525140(IDO1) 105525203(IDO2)
CJC : 100400216(IDO1) 100402049(IDO2)
SBQ : 101027731(IDO1) 101050312(IDO2)
CIMI : 108310239(IDO1) 108310249(IDO2)
ANAN : 105733495(IDO2) 105733580(IDO1)
CSYR : 103253231(IDO1) 103253232(IDO2)
MMUR : 105878169(IDO1) 105878170(IDO2)
LCAT : 123626627(IDO2) 123626628(IDO1)
PCOQ : 105820620(IDO2) 105820621(IDO1)
OGA : 100953210(IDO2) 100953516(IDO1)
MMU : 15930(Ido1) 209176(Ido2)
MCAL : 110300027(Ido2) 110300694(Ido1)
MPAH : 110337001(Ido1) 110337123(Ido2)
RNO : 66029(Ido1) 681319(Ido2)
MCOC : 116069031(Ido1) 116069032(Ido2)
ANU : 117721718(Ido2) 117721974(Ido1)
MUN : 110560029(Ido1) 132653594(Ido2)
CGE : 100754111(Ido2) 100754402(Ido1)
MAUA : 101838023(Ido2) 101839710(Ido1)
PROB : 127220347(Ido1) 127220354(Ido2)
PLEU : 114705753(Ido1) 114705759(Ido2)
MORG : 121462300(Ido2) 121462305(Ido1)
MFOT : 126504423 126504447
AAMP : 119812720(Ido2) 119813008(Ido1)
HGL : 101723386(Ido2) 101723745(Ido1)
CPOC : 100727752(Ido2) 100728309(Ido1)
CCAN : 109698340(Ido1) 109698345(Ido2)
DORD : 105991692(Ido2) 106002559(Ido1)
DSP : 122107656(Ido1) 122107660(Ido2)
PLOP : 125339452(Ido2) 125339609(Ido1)
NCAR : 124983204 124983972
MMMA : 107159629(Ido2) 107159646(Ido1)
OPI : 101519630(IDO1) 101526429(IDO2)
TUP : 102485305(IDO2) 102494474(IDO1)
GVR : 103595156(IDO2) 103608867(IDO1)
CFA : 475574(IDO1) 482846(IDO2)
CLUD : 112653230(IDO1) 112653288(IDO2)
VVP : 112916145(IDO2) 112916272(IDO1)
VLG : 121489289(IDO2) 121489290(IDO1)
NPO : 129515878(IDO1) 129515880(IDO2)
AML : 100480334(IDO2) 100480587(IDO1)
UMR : 103677106(IDO2) 103677107(IDO1)
UAH : 113245545(IDO1) 113245547(IDO2)
UAR : 123780297(IDO2) 123780317(IDO1)
MPUF : 101672897(IDO1) 101674323(IDO2)
MNP : 132006340(IDO1) 132006468(IDO2)
MLK : 131820500(IDO1) 131820524(IDO2)
NVS : 122889868(IDO2) 122919260(IDO1)
ORO : 101369080(IDO2) 101376680(IDO1)
EJU : 114224793(IDO1) 114224848(IDO2)
ZCA : 113924539(IDO2) 113924540(IDO1)
MLX : 118009935(IDO2) 118009936(IDO1)
NSU : 110573100(IDO1) 110573101(IDO2)
LWW : 102727570 102741055(IDO1) 102741357(IDO2)
FCA : 101096722(IDO2) 101096977(IDO1)
PYU : 121015606(IDO1) 121039912(IDO2)
PCOO : 112858128(IDO2) 112858555(IDO1)
PBG : 122473238(IDO2) 122473243(IDO1)
PVIV : 125163938(IDO2) 125164352(IDO1)
LRUF : 124520306 124520989
PTG : 102959839(IDO2) 102969142(IDO1)
PPAD : 109262284(IDO2) 109262285(IDO1)
HHV : 120246074(IDO1) 120246083(IDO2)
BTA : 506281(IDO1) 513810(IDO2)
BOM : 102264395(IDO1) 102267516(IDO2)
BIU : 109553529(IDO1) 109553543(IDO2)
BBUB : 102397405(IDO1) 102397944(IDO2)
BBIS : 104993210(IDO1) 104993211(IDO2)
CHX : 102184119(IDO1) 102184590(IDO2)
OAS : 100196903(IDO1) 101120548(IDO2)
BTAX : 128068368(IDO1) 128068377(IDO2)
ODA : 120865678(IDO1) 120865680(IDO2)
CCAD : 122432568(IDO2) 122432572(IDO1)
MBEZ : 129549237(IDO1) 129549238(IDO2)
SSC : 100519341(IDO2) 100519877(IDO1)
CFR : 102518520(IDO2) 106729416(IDO1)
CBAI : 105071346(IDO1) 105071511(IDO2)
CDK : 105105464(IDO1) 105105465(IDO2)
VPC : 102544039(IDO2) 102544305(IDO1)
BACU : 102998882(IDO1) 102999165(IDO2)
BMUS : 118887739(IDO1) 118887787(IDO2)
LVE : 103068351(IDO2) 103068620(IDO1)
OOR : 101286688(IDO2) 101286954(IDO1)
DLE : 111173537(IDO1) 111173538(IDO2)
PCAD : 102990011(IDO1) 102990290(IDO2)
PSIU : 116746627(IDO1) 116746850(IDO2)
NASI : 112413103(IDO1) 112413205(IDO2)
ECB : 100056686(IDO2) 106782641(IDO1)
EPZ : 103554295(IDO2) 103554296(IDO1)
EAI : 106828941(IDO1) 106828942(IDO2)
MYB : 102256119(IDO1) 102256420(IDO2)
MYD : 102755941(IDO2) 102756580(IDO1)
MMYO : 118651942(IDO1) 118652090(IDO2)
MLF : 102426253(IDO1) 102426572(IDO2)
MDT : 132228621(IDO2) 132228622(IDO1)
PKL : 118730235(IDO2) 118730629(IDO1)
EFUS : 103288165(IDO1) 103288287(IDO2)
MNA : 107523935(IDO2) 107523938(IDO1)
DRO : 112321513(IDO2) 112321553(IDO1)
SHON : 118993190(IDO1) 118993191(IDO2)
AJM : 119064992(IDO2) 119065052(IDO1)
PDIC : 114508403(IDO1) 114508713(IDO2)
PHAS : 123807675(IDO2) 123807694(IDO1)
MMF : 118623040(IDO1) 118623043(IDO2)
PPAM : 129064645(IDO1) 129064680(IDO2)
HAI : 109386258(IDO1) 109386283(IDO2)
RFQ : 117021796(IDO2) 117021797(IDO1)
PALE : 102878670(IDO2) 102896453(IDO1)
PGIG : 120595557(IDO1) 120595607(IDO2)
PVP : 105300415(IDO1) 105300983(IDO2)
RAY : 107501321(IDO1) 107501322(IDO2)
MJV : 108398102(IDO2) 108398103(IDO1)
TOD : 119256541 119256963(IDO1) 119256965(IDO2)
SARA : 101543020(IDO1) 101543560(IDO2) 101553130
SETR : 126006487(IDO2) 126007259(IDO1) 126022054
LAV : 100660395(IDO1) 100671377(IDO2)
ETF : 101651677 101651988 101652302(IDO2)
DNM : 101427072(IDO2) 101435095(IDO1) 101447628
MDO : 100032999(IDO1) 100033003(IDO2)
GAS : 123234853(IDO2) 123234854(IDO1)
SHR : 100926615 100926876(IDO2) 105749589
AFZ : 127548253 127548254 127548255
PCW : 110203204(IDO1) 110203211(IDO2)
TVP : 118840861(IDO1) 118844896(IDO2)
OAA : 100085939(IDO2) 100086385(IDO1)
PSS : 102453712(IDO2) 102455437
CCAY : 125626412(IDO1) 125626414(IDO2)
DCC : 119848555(IDO2) 119848556(IDO1)
CPIC : 101943268 101943538
CABI : 116821428 116821432
SANH : 107665200 107678376
CCAR : 109082139 109093681
CAUA : 113039681 113106758
CGIB : 127962849 128018248
LROH : 127169613 127169615
OMC : 131545248 131545889(ido1)
IPU : 108261789 108265915(ido1)
CHAR : 105902744(ido1) 105910904
TBEN : 117496919(ido1) 117499780
CGOB : 115013739 115020208
PGEO : 117452824(ido1) 117460173
GACU : 117560899 117561112(ido1)
EMAC : 134858405 134873878(ido1)
ELY : 117248703 117252223(ido1)
EFO : 125890312(ido1) 125903634
PLEP : 121944647(ido1) 121955034
SLUC : 116053927(ido1) 116055474
ECRA : 117944249(ido1) 117960787
PFLV : 114556148 114562965 114572566
MSAM : 119891997(ido1) 119917540
SCHU : 122876973(ido1) 122884667
CUD : 121509246(ido1) 121510772
ALAT : 119019532(ido1) 119033434
OAU : 116310246(ido1) 116322211
OML : 112147981(ido1) 112161927
CSAI : 133450358(ido1) 133463681
PRET : 103470503 103476765
PFOR : 103133561 103145719
PLAI : 106936396 106949737
PMEI : 106914144 106932858
GAF : 122827979(ido1) 122842685
PPRL : 129359800 129372209(ido1)
CTUL : 119776059 119783931(ido1)
GMU : 124859383 124877638 124877910
KMR : 108236475(ido1) 108242928
NWH : 119413466(ido1) 119419086
AOCE : 111566901 111578649
MCEP : 125011925(ido1) 125018475
CSEM : 103387655 103398229
SSEN : 122769196(ido1) 122781502
HHIP : 117768409(ido1) 117775696
HSP : 118115278(ido1) 118119113
PPLT : 128438272(ido1) 128453844
SMAU : 118284113 118314580(ido1)
LCF : 108878793(ido1) 108897278
SLAL : 111649548 111663420 111663848
XGL : 120796675 120804813(ido1)
MALB : 109956908 109960434
BSPL : 114841969 114863162(ido1)
SJO : 128364091(ido1) 128372507
SASA : 106577031 106579858 106585586
STRU : 115164544 115193722 115200101
OTW : 112248460 112253538 112263992(ido1)
OMY : 110525639 110529307 110536009(ido1)
OGO : 124034340 124036279 124041233
ONE : 115111577 115135078 115140017
OKI : 109879368 109888797 109894902
OKE : 118358316 118369741 118393182
SALP : 111951597 111957692 111975044
SNH : 120017416 120017668 120063219
CCLU : 121530873(ido1) 121553712 121584820
PKI : 111838843 111842017 111842059 111849886
AANG : 118212365 118237252(ido1)
PSPA : 121302180 121302245 121303059 121303061(ido1)
ARUT : 117397802 117397807 117962507 117971679
PSEX : 120539301 120539486(ido1)
SPU : 100893352 577419 754565
LPIC : 129263163 129263694 129269297 129270335
APLC : 110980378 110980392
ARUN : 117292357 117292421
LGI : LOTGIDRAFT_168391 LOTGIDRAFT_168398 LOTGIDRAFT_236096
PVUL : 126810606 130010305
HRF : 124132381 124132382 124145837 124145838
HRJ : 124256228 124256245 124287374 124287429
MYI : 110441193 110450994 110450995 110450996 110461080
PMAX : 117329726 117329738 117329744 117329747 117338256
DPOL : 127867275 127868168
LJP : 135470330 135470968 135471675
LAK : 106161424 106162758 106162759 106162760 106162816 106176942 106176946 106182094
EPA : 110240490 110250165 110250194
AMIL : 114958243 114958245
DGT : 114538136 114539262 114539439 114544431
AQU : 105312930 105315377 105315605
CRE : CHLRE_17g710200v5 CHLRE_17g713700v5
TPF : TPHA_0B01500(TPHA0B01500)
TDL : TDEL_0C03080(TDEL0C03080)
SPAA : SPAPADRAFT_63090(BNA2)
CAL : CAALFM_C500800CA(CaO19.583)
YLI : 2908695(YALI2_E00979g)
NCR : NCU01402 NCU05752 NCU09184
NTE : NEUTE1DRAFT43213(NEUTE1DRAFT_43213) NEUTE1DRAFT76034(NEUTE1DRAFT_76034) NEUTE1DRAFT86563(NEUTE1DRAFT_86563)
SMP : 10801219(SMAC4_08377) 10801685(SMAC4_08990) 10810851(SMAC4_08948)
PAN : PODANSg2504 PODANSg762 PODANSg7893
PBEL : QC761_201070 QC761_401340(BNA2) QC761_700760
PPSD : QC762_201070 QC762_401340(BNA2) QC762_700760
PPSP : QC763_201070 QC763_401340(BNA2) QC763_700760
PPSA : QC764_201070 QC764_401340(BNA2) QC764_700760
TTT : THITE_2106420 THITE_2110987 THITE_2120385
MTM : MYCTH_2300294 MYCTH_2303249 MYCTH_2307600
CTHR : CTHT_0045730 CTHT_0051700 CTHT_0072620
MGR : MGG_00755 MGG_13773 MGG_14348
PPEI : PpBr36_05444 PpBr36_08387 PpBr36_10865
PGRI : PgNI_02884 PgNI_08067 PgNI_08551
TMN : UCRPA7_1826 UCRPA7_5970 UCRPA7_8045
SSCK : SPSK_03376 SPSK_05234 SPSK_09104
FGR : FGSG_02657 FGSG_04828 FGSG_09040
FPU : FPSE_00364 FPSE_04050 FPSE_07323
FPOA : FPOAC1_002785 FPOAC1_007667 FPOAC1_012709
FVN : FVRRES_03100 FVRRES_08130 FVRRES_13909
FVR : FVEG_03512 FVEG_06565 FVEG_09278
FOX : FOXG_05659 FOXG_08978 FOXG_10631
NHE : NECHADRAFT_70501 NECHADRAFT_70795 NECHADRAFT_85363
FFC : NCS54_00852400 NCS54_00996000 NCS54_01207800
FKR : NCS57_00896000 NCS57_00990300 NCS57_01198600
FMU : J7337_003526 J7337_005128 J7337_009220
TRE : TRIREDRAFT_123550 TRIREDRAFT_54260 TRIREDRAFT_64330
TRR : M419DRAFT_103027 M419DRAFT_82203 M419DRAFT_84917
TATV : 25781760(TrAtP1_008959) 25784169(TrAtP1_003159) 25784846(TrAtP1_006780)
TASP : 36608505(TrAFT101_006002) 36608907(TrAFT101_006863) 36611727(TrAFT101_002497)
MAW : 19246780(BNA2) 19246933(J3458_005693) 19249775(J3458_002357)
MAJ : MAA_00343 MAA_03016 MAA_05241
MBRN : 26237397(BNA2_0) 26241496(BNA2_1) 26243149(BNA2_2)
PCHM : VFPPC_08814 VFPPC_09609 VFPPC_10339 VFPPC_11154 VFPPC_16145
CMT : CCM_02833 CCM_03688 CCM_06695
AMUS : LMH87_007130 LMH87_007825 LMH87_008562 LMH87_012010
PLJ : 28885236(PLICBS_006807) 28890649(PLICBS_004994) 28892308(PLICBS_009945) 28892972(PLICBS_003894)
PTKZ : JDV02_001859(BNA2_1) JDV02_005489(BNA2_2) JDV02_006827 JDV02_008848
VAL : VDBG_00295 VDBG_04314 VDBG_09667
VDA : VDAG_05624 VDAG_08582 VDAG_10523
CFJ : CFIO01_11397 CFIO01_12906 CFIO01_13114
CLUP : CLUP02_10126 CLUP02_10625 CLUP02_17214
CHIG : CH63R_06938 CH63R_09055 CH63R_09419
SAPO : SAPIO_CDS10590 SAPIO_CDS9355
ELA : UCREL1_5860 UCREL1_7574 UCREL1_7759
PFY : PFICI_02204 PFICI_03646 PFICI_06657 PFICI_14031
SSL : SS1G_00858 SS1G_08222 SS1G_10307
BFU : BCIN_12g01060 BCIN_14g01360 BCIN_14g04320
MBE : MBM_00447 MBM_04791 MBM_09099
PSCO : LY89DRAFT_46206 LY89DRAFT_704456 LY89DRAFT_732805
GLZ : GLAREA_00603 GLAREA_03347 GLAREA_11411
ANI : ANIA_01858 ANIA_02509 ANIA_09108
AFM : AFUA_3G14250 AFUA_4G09830 AFUA_7G02010
ACT : ACLA_041740 ACLA_049060 ACLA_065510
NFI : NFIA_063050 NFIA_106220 NFIA_114740
AOR : AO090003001248 AO090020000618 AO090038000578
ANG : An04g07210 An09g04250 An12g00660
AFV : AFLA_000425 AFLA_009061 AFLA_010029
ALUC : AKAW2_30285A AKAW2_40495S AKAW2_81033S
ACHE : ACHE_10703A ACHE_20065A ACHE_31323A ACHE_60068A ACHE_70219S ACHE_70687A
APUU : APUU_21222A APUU_30231S APUU_31574S
PCS : N7525_002475 N7525_005148 N7525_007796
PDP : PDIP_24520 PDIP_25600 PDIP_56120
POU : POX_b02054 POX_e06475 POX_g08572
TMF : EYB26_000580 EYB26_006842 EYB26_009539
TRG : TRUGW13939_02130 TRUGW13939_04063 TRUGW13939_11421
CIM : CIMG_00126 CIMG_07803
CPW : CPC735_041970 CPC735_060120
URE : UREG_00231 UREG_02134
PBL : PAAG_05853 PAAG_06866
PBN : PADG_04329 PADG_06139
ABE : ARB_03636 ARB_04584 ARB_05733
TVE : TRV_00864 TRV_01957 TRV_04509
AJE : HCAG_01148 HCAG_04432
BGH : BDBG_04038 BDBG_06623
PNO : SNOG_02815 SNOG_10574 SNOG_10794
PTE : PTT_07650 PTT_08299 PTT_13994
PTRR : 6339971(PtrM4_024560) 6348088(PtrM4_086460) 6348156(PtrM4_085730)
BZE : COCCADRAFT_1250 COCCADRAFT_97046
BSC : COCSADRAFT_102379 COCSADRAFT_138733
BOR : COCMIDRAFT_1657 COCMIDRAFT_95092
AALT : CC77DRAFT_1023915 CC77DRAFT_123730
ARAB : EKO05_0001381 EKO05_0007622 EKO05_0007878
ZTR : MYCGRDRAFT_52885 MYCGRDRAFT_73635 MYCGRDRAFT_75056
PFJ : MYCFIDRAFT_215476 MYCFIDRAFT_48024 MYCFIDRAFT_56678
FFU : CLAFUR5_00304 CLAFUR5_06900 CLAFUR5_12265
CBET : CB0940_00866 CB0940_06399 CB0940_09211 CB0940_11439
NPA : UCRNP2_2918 UCRNP2_4546 UCRNP2_9460
TML : GSTUM_00005398001 GSTUM_00007145001
CDEP : 91089766(L203_105557)
TASA : A1Q1_00029 A1Q1_00097
CCAC : CcaHIS019_0104590(CcaverHIS019_0104590) CcaHIS019_0113040(CcaverHIS019_0113040)
TVS : TRAVEDRAFT_118782 TRAVEDRAFT_168783
DSQ : DICSQDRAFT_49513 DICSQDRAFT_66685
SHS : STEHIDRAFT_128669 STEHIDRAFT_49151 STEHIDRAFT_96831
HIR : HETIRDRAFT_326738 HETIRDRAFT_417390 HETIRDRAFT_43434
PSQ : PUNSTDRAFT_100537 PUNSTDRAFT_102652 PUNSTDRAFT_53490 PUNSTDRAFT_60614
ADL : AURDEDRAFT_103636 AURDEDRAFT_168315
FME : FOMMEDRAFT_164852 FOMMEDRAFT_29270
GTR : GLOTRDRAFT_122534 GLOTRDRAFT_36830 GLOTRDRAFT_46282
RSX : RhiXN_02473 RhiXN_02769 RhiXN_02832 RhiXN_04477
LBC : LACBIDRAFT_157851 LACBIDRAFT_253793 LACBIDRAFT_253815 LACBIDRAFT_256000 LACBIDRAFT_257063 LACBIDRAFT_306113
CCI : CC1G_01112 CC1G_02499 CC1G_12399
ABP : AGABI1DRAFT107428(AGABI1DRAFT_107428) AGABI1DRAFT34575(AGABI1DRAFT_34575) AGABI1DRAFT60207(AGABI1DRAFT_60207) AGABI1DRAFT85862(AGABI1DRAFT_85862)
ABV : AGABI2DRAFT135051(AGABI2DRAFT_135051) AGABI2DRAFT177539(AGABI2DRAFT_177539) AGABI2DRAFT177540(AGABI2DRAFT_177540) AGABI2DRAFT64740(AGABI2DRAFT_64740)
MPR : MPER_05176 MPER_12716
MRR : Moror_12110 Moror_5206 Moror_8344 Moror_9957 Moror_9958
MORE : E1B28_000370 E1B28_009296 E1B28_010883 E1B28_010889
SCM : SCHCO_02608091(SCHCODRAFT_02608091) SCHCO_02640585(SCHCODRAFT_02640585) SCHCO_02643132(SCHCODRAFT_02643132) SCHCO_02673121(SCHCODRAFT_02673121)
CPUT : CONPUDRAFT_135908 CONPUDRAFT_135912 CONPUDRAFT_48837
SLA : SERLADRAFT_467213 SERLADRAFT_476036
SGRA : EX895_001163 EX895_001261
PGR : PGTG_06521 PGTG_09355
PTRC : PtA15_16A61 PtA15_8A651
PSTR : Pst134EA_015643 Pst134EA_015685 Pst134EA_028861 Pst134EA_031248
MLR : MELLADRAFT_117589 MELLADRAFT_25201 MELLADRAFT_78815 MELLADRAFT_90083
RIE : OCT59_010426 OCT59_010427 OCT59_017638
TET : TTHERM_00035520 TTHERM_00035530
» show all
Taxonomy
Reference
Authors
Yamamoto S, Hayaishi O.
Title
Tryptophan pyrrolase of rabbit intestine. D- and L-tryptophan-cleaving enzyme or enzymes.
Journal
J Biol Chem 242:5260-6 (1967)
Reference
Authors
Yasui H, Takai K, Yoshida R, Hayaishi O.
Title
Interferon enhances tryptophan metabolism by inducing pulmonary indoleamine 2,3-dioxygenase: its possible occurrence in cancer patients.
Journal
Sequence
Reference
Authors
Takikawa O, Yoshida R, Kido R, Hayaishi O
Title
Tryptophan degradation in mice initiated by indoleamine 2,3-dioxygenase.
Journal
J Biol Chem 261:3648-53 (1986)
Sequence
Reference
Authors
Hirata F, Ohnishi T, Hayaishi O.
Title
Indoleamine 2,3-dioxygenase. Characterization and properties of enzyme. O2- complex.
Journal
J Biol Chem 252:4637-42 (1977)
Reference
Authors
Dang Y, Dale WE, Brown OR
Title
Comparative effects of oxygen on indoleamine 2,3-dioxygenase and tryptophan 2,3-dioxygenase of the kynurenine pathway.
Journal
Sequence
Reference
Authors
Littlejohn TK, Takikawa O, Truscott RJ, Walker MJ.
Title
Asp274 and his346 are essential for heme binding and catalytic function of human indoleamine 2,3-dioxygenase.
Journal
Sequence
Reference
Authors
Thomas SR, Stocker R.
Title
Redox reactions related to indoleamine 2,3-dioxygenase and tryptophan metabolism along the kynurenine pathway.
Journal
Reference
Authors
Sono M.
Title
Spectroscopic and equilibrium studies of ligand and organic substrate binding to indolamine 2,3-dioxygenase.
Journal
Other DBs
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