 | | DRUG: Perindopril erbumine | |
| Entry |
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| Name |
Perindopril erbumine (JAN/USP);
Aceon (TN) |
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| Product |
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| Generic |
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| Formula |
C19H32N2O5. C4H11N
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| Exact mass |
441.3203
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| Mol weight |
441.60
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| Structure |
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| Simcomp |
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| Class |
Cardiovascular agent
DG01925 Renin-angiotensin system inhibitor
DG01501 Angiotensin-converting enzyme inhibitor
DG03231 Antihypertensive
DG01501 Angiotensin-converting enzyme inhibitor
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| Remark |
| Therapeutic category: | 2144 |
| Product (DG00337): | D00624<JP/US> |
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| Efficacy |
Antihypertensive, Angiotensin-converting enzyme inhibitor |
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| Disease |
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| Comment |
Active form of prodrug: Perindoprilat [CPD: C21517]
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| Target |
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| Pathway |
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C09 AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
C09A ACE INHIBITORS, PLAIN
C09AA ACE inhibitors, plain
C09AA04 Perindopril
D00624 Perindopril erbumine (JAN/USP) <JP/US>
USP drug classification [BR:br08302]
Cardiovascular Agents
Angiotensin-converting Enzyme (ACE) Inhibitors
Perindopril
D00624 Perindopril erbumine (JAN/USP)
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
21 Cardiovascular agents
214 Antihypertensives
2144 Angiotensin converting enzyme inhibitors
D00624 Perindopril erbumine (JAN/USP)
Drug groups [BR:br08330]
Cardiovascular agent
DG01925 Renin-angiotensin system inhibitor
DG01501 Angiotensin-converting enzyme inhibitor
DG00337 Perindopril
D00624 Perindopril erbumine
DG03231 Antihypertensive
DG01501 Angiotensin-converting enzyme inhibitor
DG00337 Perindopril
D00624 Perindopril erbumine
Drug classes [BR:br08332]
Cardiovascular agent
DG01501 Angiotensin-converting enzyme inhibitor
D00624 Perindopril erbumine
DG03231 Antihypertensive
D00624 Perindopril erbumine
Target-based classification of drugs [BR:br08310]
Peptidases and inhibitors
Metallo peptidases
Family M2
ACE (CD143)
D00624 Perindopril erbumine (JAN/USP) <JP/US>
Prodrugs [br08324.html]
D00624
Drug groups [BR:br08330]
Cardiovascular agent
DG01925 Renin-angiotensin system inhibitor
DG01501 Angiotensin-converting enzyme inhibitor
DG00337 Perindopril
DG03231 Antihypertensive
DG01501 Angiotensin-converting enzyme inhibitor
DG00337 Perindopril
Prodrugs [br08324.html]
DG00337
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 31
1 N1y N 24.1851 -20.1780
2 C1y C 25.4694 -20.7383
3 C1y C 24.3427 -18.7826
4 C5a C 22.9767 -20.8843
5 C1y C 26.4093 -19.6992
6 C1x C 25.9015 -22.0694
7 C1x C 25.7146 -18.4908
8 C6a C 24.3311 -17.3758
9 C1c C 21.7623 -20.1837
10 O5a O 22.9825 -22.2854
11 C1x C 27.7812 -19.9970
12 C1x C 27.2733 -22.3671
13 O6a O 25.5336 -16.6636
14 O6a O 23.1109 -16.6869
15 N1b N 20.5481 -20.8843
16 C1a C 21.7683 -18.7826
17 C1x C 28.2073 -21.3280
18 C1c C 19.3397 -20.1897
19 C7a C 19.3340 -18.7886
20 C1b C 18.1255 -20.8960
21 O7a O 20.5481 -18.0880
22 O6a O 18.1138 -18.0938
23 C1b C 16.9112 -20.2071
24 C1b C 20.6122 -16.6869
25 C1a C 15.7027 -20.8960
26 C1a C 19.3280 -15.9923
27 C1d C 32.0427 -20.0612
28 C1a C 30.6475 -20.0612
29 C1a C 33.4438 -20.0612
30 C1a C 32.0369 -21.4565
31 N1a N 32.0544 -18.6601
BOND 31
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 1
7 3 8 1 #Down
8 4 9 1
9 4 10 2
10 5 11 1
11 6 12 1
12 8 13 1
13 8 14 2
14 9 15 1
15 9 16 1 #Up
16 11 17 1
17 15 18 1
18 18 19 1 #Up
19 18 20 1
20 19 21 1
21 19 22 2
22 20 23 1
23 21 24 1
24 23 25 1
25 24 26 1
26 5 7 1
27 12 17 1
28 27 28 1
29 27 29 1
30 27 30 1
31 27 31 1
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