| | NETWORK: N00982 | |
Entry |
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Name |
Mutation-caused aberrant Htt to p53-mediated transcription
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Definition |
HTT* -> TP53 => (BAX,BBC3) |
Expanded |
3064v1 -> 7157 => (581,27113) |
Class |
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Type |
Variant
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Pathway |
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Disease |
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Gene |
7157 | TP53; tumor protein p53 |
581 | BAX; BCL2 associated X, apoptosis regulator |
27113 | BBC3; BCL2 binding component 3 |
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Variant |
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Reference |
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Authors |
Bae BI, Xu H, Igarashi S, Fujimuro M, Agrawal N, Taya Y, Hayward SD, Moran TH, Montell C, Ross CA, Snyder SH, Sawa A |
Title |
p53 mediates cellular dysfunction and behavioral abnormalities in Huntington's disease. |
Journal |
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Reference |
|
Authors |
La Spada AR, Morrison RS |
Title |
The power of the dark side: Huntington's disease protein and p53 form a deadly alliance. |
Journal |
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LinkDB |
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