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KEGG   NETWORK: N00990
Entry
N00990                      Network                                
Name
Electron transfer in Complex III
Definition
QH2 -- CxIII -> CytC
  Expanded
C00390 -- (7386+4519+1537+7384+7385+(440567,7388)+7381+27089+29796+10975) -> C00524
Class
nt06252 Mitochondrial ROS formation (cancer)
nt06463 Parkinson disease
nt06461 Huntington disease
nt06466 Pathways of neurodegeneration
Type
Reference
Pathway
hsa00190  Oxidative phosphorylation
Gene
7386  UQCRFS1; ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
4519  CYTB; cytochrome b
1537  CYC1; cytochrome c1
7384  UQCRC1; ubiquinol-cytochrome c reductase core protein 1
7385  UQCRC2; ubiquinol-cytochrome c reductase core protein 2
440567  UQCRHL; ubiquinol-cytochrome c reductase hinge protein like
7388  UQCRH; ubiquinol-cytochrome c reductase hinge protein
7381  UQCRB; ubiquinol-cytochrome c reductase binding protein
27089  UQCRQ; ubiquinol-cytochrome c reductase complex III subunit VII
29796  UQCR10; ubiquinol-cytochrome c reductase, complex III subunit X
10975  UQCR11; ubiquinol-cytochrome c reductase, complex III subunit XI
Metabolite
C00390  Ubiquinol
C00524  Cytochrome c
Reference
PMID:27873462
  Authors
Golpich M, Amini E, Mohamed Z, Azman Ali R, Mohamed Ibrahim N, Ahmadiani A
  Title
Mitochondrial Dysfunction and Biogenesis in Neurodegenerative diseases: Pathogenesis and Treatment.
  Journal
CNS Neurosci Ther 23:5-22 (2017)
DOI:10.1111/cns.12655
Reference
PMID:10066163
  Authors
Saraste M
  Title
Oxidative phosphorylation at the fin de siecle.
  Journal
Science 283:1488-93 (1999)
DOI:10.1126/science.283.5407.1488
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