| | NETWORK: N01024 | |
Entry |
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Name |
Mutation-inactivated PRKN to Parkin-mediated ubiquitination
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Definition |
UBCH7/8 // PRKN* // CDCREL1 |
Expanded |
(7332,9246) // 5071v1 // 5413 |
Class |
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Type |
Variant
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Pathway |
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Disease |
|
Gene |
7332 | UBE2L3; ubiquitin conjugating enzyme E2 L3 |
9246 | UBE2L6; ubiquitin conjugating enzyme E2 L6 |
5071 | PRKN; parkin RBR E3 ubiquitin protein ligase |
|
Variant |
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Reference |
|
Authors |
Zhang Y, Gao J, Chung KK, Huang H, Dawson VL, Dawson TM. |
Title |
Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1. |
Journal |
|
Reference |
|
Authors |
Dev KK, van der Putten H, Sommer B, Rovelli G |
Title |
Part I: parkin-associated proteins and Parkinson's disease. |
Journal |
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LinkDB |
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DBGET integrated database retrieval system