KEGG NETWORK: N01059

NETWORK: N01059

Entry

N01059                      Network

Name

Mutation-inactivated DJ1 to KEAP1-NRF2 signaling pathway

Definition

DJ1* // NRF2 // TRX1

Expanded

11315v1 // 4780 // 7295

Class

nt06463 Parkinson disease

Type

Variant

Pathway

hsa05012

Parkinson disease

Disease

H00057

Parkinson disease

Gene

11315

PARK7; Parkinsonism associated deglycase

4780	NFE2L2; nuclear factor, erythroid 2 like 2

7295	TXN; thioredoxin

Variant

11315v1 (DJ1*) PARK7 mutation

Reference

PMID:31054074

Authors

Dolgacheva LP, Berezhnov AV, Fedotova EI, Zinchenko VP, Abramov AY

Title

Role of DJ-1 in the mechanism of pathogenesis of Parkinson's disease.

Journal

J Bioenerg Biomembr 51:175-188 (2019)
DOI:10.1007/s10863-019-09798-4

Reference

PMID:28823929

Authors

Biosa A, Sandrelli F, Beltramini M, Greggio E, Bubacco L, Bisaglia M

Title

Recent findings on the physiological function of DJ-1: Beyond Parkinson's disease.

Journal

Neurobiol Dis 108:65-72 (2017)
DOI:10.1016/j.nbd.2017.08.005

Reference

PMID:31261912

Authors

Francisqueti-Ferron FV, Ferron AJT, Garcia JL, Silva CCVA, Costa MR, Gregolin CS, Moreto F, Ferreira ALA, Minatel IO, Correa CR

Title

Basic Concepts on the Role of Nuclear Factor Erythroid-Derived 2-Like 2 (Nrf2) in Age-Related Diseases.

Journal

Int J Mol Sci 20:E3208 (2019)
DOI:10.3390/ijms20133208

LinkDB

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