| | NETWORK: N01203 | |
Entry |
|
Name |
Scrapie conformation PrPSc to Notch singling pathway
|
Definition |
PRNP* -> NOTCH1 |
Expanded |
5621v1 -> 4851 |
Class |
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Type |
Variant
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Pathway |
|
Disease |
|
Gene |
4851 | NOTCH1; notch receptor 1 |
|
Variant |
5621v1 (PRNP*) PRNP scrapie conformation
|
Reference |
|
Authors |
Ishikura N, Clever JL, Bouzamondo-Bernstein E, Samayoa E, Prusiner SB, Huang EJ, DeArmond SJ |
Title |
Notch-1 activation and dendritic atrophy in prion disease. |
Journal |
|
Reference |
|
Authors |
Dearmond SJ, Bajsarowicz K |
Title |
PrPSc accumulation in neuronal plasma membranes links Notch-1 activation to dendritic degeneration in prion diseases. |
Journal |
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LinkDB |
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