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KEGG   REACTION: R00264
Entry
R00264                      Reaction                               
Name
2,5-dioxopentanoate:NADP+ 5-oxidoreductase
Definition
2,5-Dioxopentanoate + NADP+ + H2O <=> 2-Oxoglutarate + NADPH + H+
Equation
C00433 + C00006 + C00001 <=> C00026 + C00005 + C00080
Reaction class
RC00001  C00005_C00006
RC00080  C00026_C00433
Enzyme
1.2.1.3         1.2.1.26
Pathway
rn00040  Pentose and glucuronate interconversions
rn00053  Ascorbate and aldarate metabolism
rn00470  D-Amino acid metabolism
rn01100  Metabolic pathways
Module
M00948  Hydroxyproline degradation, trans-4-hydroxy-L-proline => 2-oxoglutarate
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.3
     R00264  2,5-Dioxopentanoate + NADP+ + H2O <=> 2-Oxoglutarate + NADPH + H+
    1.2.1.26
     R00264  2,5-Dioxopentanoate + NADP+ + H2O <=> 2-Oxoglutarate + NADPH + H+
Orthology
K00128  aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
K13877  2,5-dioxopentanoate dehydrogenase [EC:1.2.1.26]
K19588  2,5-dioxopentanoate dehydrogenase [EC:1.2.1.26]
Other DBs
RHEA: 11299
LinkDB

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