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KEGG   REACTION: R12090
Entry
R12090                      Reaction                               
Name
chanoclavine-I aldehyde:NAD+ oxidoreductase
Definition
Dihydrochanoclavine-I aldehyde + NADP+ <=> Chanoclavine-I aldehyde + NADPH + H+
Equation
C21897 + C00006 <=> C20379 + C00005 + C00080
Reaction class
RC03527  C20379_C21897
Enzyme
1.3.1.100
Pathway
rn00901  Indole alkaloid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00964  Fumigaclavine biosynthesis, chanoclavine-I aldehyde => fumigaclavine C
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.100
     R12090  Dihydrochanoclavine-I aldehyde + NADP+ <=> Chanoclavine-I aldehyde + NADPH + H+
Orthology
K19182  chanoclavine-I aldehyde reductase [EC:1.3.1.100]
Reference
1  [PMID:20526482]
  Authors
Wallwey C, Matuschek M, Xie XL, Li SM
  Title
Ergot alkaloid biosynthesis in Aspergillus fumigatus: Conversion of chanoclavine-I aldehyde to festuclavine by the festuclavine synthase FgaFS in the presence of the old yellow enzyme FgaOx3.
  Journal
Org Biomol Chem 8:3500-8 (2010)
DOI:10.1039/c003823g
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