KEGG REACTION: R13220

REACTION: R13220

Entry

R13220                      Reaction

Name

dihydrotestosterone:NADP+ 17-oxidoreductase

Definition

5alpha-Androstane-3,17-dione + NADPH + H+ <=> Dihydrotestosterone + NADP+

Equation

C00674 + C00005 + C00080 <=> C03917 + C00006

Reaction class

RC00127

C00674_C03917

Enzyme

1.1.1.51 1.1.1.64

Pathway

rn00140

Steroid hormone biosynthesis

rn01100

Metabolic pathways

Brite

Enzymatic reactions [BR:br08201]
1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.51
     R13220  5alpha-Androstane-3,17-dione + NADPH + H+ <=> Dihydrotestosterone + NADP+
    1.1.1.64
     R13220  5alpha-Androstane-3,17-dione + NADPH + H+ <=> Dihydrotestosterone + NADP+

Orthology

K04119

aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]

K10207

testosterone 17beta-dehydrogenase (NADP+) [EC:1.1.1.64]

LinkDB

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