Clonorchiasis is an infectious disease of the biliary passages caused by Clonorchis sinensis of the family Opisthorchiidae. Clonorchis sinensis, the most common human liver fluke, is endemic in East Asia. The human and animal reservoir hosts acquire the infection from the ingestion of raw fish (the second intermediate hosts) containing infectious metacercariae.
The first intermediate hosts: freshwater snails (predominantly of the genus Parafossarulus and Bithynia)
The second intermediate hosts: freshwater fish (predominantly of the family Cyprinidae)
