CO
2 and N
2 injection is an effective enhanced oil recovery technology in the oilfield especially for low-permeability and extra low-permeability reservoirs. However, these processes can induce an asphaltene deposition during oil production. Asphaltene-deposition-induced formation damage is a fairly severe problem. Therefore,
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CO
2 and N
2 injection is an effective enhanced oil recovery technology in the oilfield especially for low-permeability and extra low-permeability reservoirs. However, these processes can induce an asphaltene deposition during oil production. Asphaltene-deposition-induced formation damage is a fairly severe problem. Therefore, predicting the likelihood of asphaltene deposition in reservoir conditions is crucial. This paper presents the results of flash separation experiments used to investigate the composition of crude oil in shallow and buried-hill reservoirs. Then, PVTsim Nova is used to simulate the composition change and asphaltene deposition of crude oil. Simulation tests indicate that the content of light components C
1-C
4 and heavy components C
36+ decrease with increasing CO
2 and N
2 injection volumes. However, the extraction of CO
2 is significantly stronger than that of N
2. In shallow reservoirs, as the CO
2 injection volume increases, the deposition pressure range decreases and asphaltenes are easily deposited. Conversely, the asphaltene deposition pressure of crude oil injected with N
2 is higher and will not cause serious asphaltene deposition. When the CO
2-N
2 injection ratio reaches 1:1, the deposition pressure range shows a significant transition. In buried-hill reservoirs, asphaltene deposition is unlikely to occur with CO
2, N
2, and a gas mixture injection.
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