Feasibility and Performance of Free-Hand Single-Photon Computed Tomography/Ultrasonography for Preoperative Parathyroid Adenoma Localization: A Pilot Study
Abstract
:1. Introduction
2. Materials and Methods
3. Results
3.1. Patient Characteristics
3.2. Detection Capacity
3.3. Feasibility
4. Discussion
4.1. Feasibility
4.2. Performance
4.3. Limitations and Perspectives
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Sex (%) | Age (years) Mean ± SD | BMI (Kg/m2) Mean ± SD | PTH Level * Pre-Surgery (ng/L) Mean ± SD [12] | PTH Level * Post-Surgery (ng/L) Mean ± SD [9] | Ca Level ** Pre-Surgery (mmol/L) Mean ± SD [12] | Ca Level ** Post-Surgery (mmol/L) Mean ± SD [10] | Number of Lesions Detected on Imaging | Size of Lesions Measured on SPECT/CT (mm) Mean ± SD | Depth of Lesions Measured on SPECT/CT (mm) Mean ± SD |
---|---|---|---|---|---|---|---|---|---|
Female 4 (33%) Male 8 (67%) | 60 ± 16 | 25.5 ± 5.2 | 107.5 ± 50.9 | 49.1 ± 29.9 | 2.7 ± 0.1 | 2.3 ± 0.9 | 16 | 11.4 ± 4.2 | 33.1 ± 8.9 |
Detected (12 Patients) | Undetected According to SPECT/CT (12 Patients) | Undetected According to Surgery (9 Patients) | Undetected According to Gold STD (12 Patients) | |
---|---|---|---|---|
Per patient (n = 12) | ||||
US | 10 | 2 | 1 | 2 |
SPECT/CT | 12 | – | 0 | 0 |
fhSPECT/US | 7 | 5 | 3 | 5 |
Per lesion (n = 17) | ||||
US | 10 | 6 | 4 | 7 |
SPECT/CT | 16 | – | 1 | 1 |
fhSPECT/US | 7 | 9 | 7 | 10 |
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Champendal, M.; Jreige, M.; Nicod Lalonde, M.; Pires Jorge, J.A.; Matter, M.; Sykiotis, G.P.; Prior, J.O. Feasibility and Performance of Free-Hand Single-Photon Computed Tomography/Ultrasonography for Preoperative Parathyroid Adenoma Localization: A Pilot Study. Diagnostics 2023, 13, 2200. https://doi.org/10.3390/diagnostics13132200
Champendal M, Jreige M, Nicod Lalonde M, Pires Jorge JA, Matter M, Sykiotis GP, Prior JO. Feasibility and Performance of Free-Hand Single-Photon Computed Tomography/Ultrasonography for Preoperative Parathyroid Adenoma Localization: A Pilot Study. Diagnostics. 2023; 13(13):2200. https://doi.org/10.3390/diagnostics13132200
Chicago/Turabian StyleChampendal, Mélanie, Mario Jreige, Marie Nicod Lalonde, José A. Pires Jorge, Maurice Matter, Gerasimos P. Sykiotis, and John O. Prior. 2023. "Feasibility and Performance of Free-Hand Single-Photon Computed Tomography/Ultrasonography for Preoperative Parathyroid Adenoma Localization: A Pilot Study" Diagnostics 13, no. 13: 2200. https://doi.org/10.3390/diagnostics13132200