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Brain Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Deep into the Brain: Artificial Intelligence in Brain Diseases—2nd Edition

edited by

Gianluca Borghini

Pietro Aricò

Gaia Romana Pellicano

and

Alessandra Anzolin

submission deadline 31 Mar 2025 | 1 articles | Viewed by 1093 | Submission Open

Keywords: artificial intelligence; brain diseases; neurological disorders; machine learning; deep learning; neuroimaging; neuroscience; neurophysiological measures; mental states; multimodal approach

(This special issue belongs to the Section Computational Neuroscience and Neuroinformatics)

Computational Neuroscience and Artificial Intelligence: Cross-Talks and Interrelated Contributions

edited by

Ali Yadollahpour

submission deadline 31 Mar 2025 | 1 articles | Viewed by 617 | Submission Open

Keywords: computational neuroscience; cognitive neuroscience; artificial intelligence; machine learning; precision medicine; early diagnosis; treatment

(This special issue belongs to the Section Computational Neuroscience and Neuroinformatics)

Neural Mechanisms Underlying Sensorimotor Learning and Plasticity: Novel Advances and Future Perspectives

edited by Giacomo Guidali

submission deadline 31 Mar 2025 | Viewed by 270 | Submission Open

Keywords: sensorimotor learning; brain plasticity; cognitive neuroscience; neurophysiology; non-invasive brain stimulation; EEG; neuromodulation; motor system; visual system; somatosensory system

(This special issue belongs to the Section Systems Neuroscience)

Neuropsychological Exploration of Spatial Cognition and Navigation

edited by

Jose Manuel Cimadevilla

Laura Piccardi

Raffaella Nori

Maria Kozhevnikov

and Sean Commins

submission deadline 31 Mar 2025 | Viewed by 98 | Submission Open

Keywords: spatial memory; neuropsychological; spatial navigation; cognitive disorder; Alzheimer’ s disease; spatial cognition; dementia; brain Function

(This special issue belongs to the Section Neuropsychology)

Clinical Research on Tourette Syndrome: Advances and Challenges

edited by José Fidel Baizabal-Carvallo

submission deadline 31 Mar 2025 | Viewed by 74 | Submission Open

Keywords: tics; Tourette’ s syndrome; chronic tic disorder; secondary tic disorder; attention-deficit/hyperactivity disorder; obsessive-compulsive disorder; biomarkers

(This special issue belongs to the Section Systems Neuroscience)

Management and Healthcare for Patients With Psychiatric Diseases

edited by Clifton Chow

submission deadline 31 Mar 2025 | Viewed by 29 | Submission Open

Keywords: psychiatric diseases; management; healthcare; neuropsychology; schizophrenia; depression; bipolar disorder; digital health; patient-centered care; cognitive rehabilitation

(This special issue belongs to the Section Psychiatric Diseases)

Reading, Spelling, and Visual Functions in Patients with Posterior Cortical Atrophy

edited by

Deepti Putcha

submission deadline 1 Apr 2025 | Viewed by 235 | Submission Open

Keywords: Alzheimer’ s disease; atypical AD; visual variant; posterior cortical atrophy; reading; spelling; writing; visual; visuospatial

(This special issue belongs to the Section Neurodegenerative Diseases)

Combining Psychotherapy and Brain Stimulation: A Collaborative Approach

edited by

Alessandra Vergallito

submission deadline 6 Apr 2025 | Viewed by 31 | Submission Open

Keywords: TMS; tDCS; noninvasive brain stimulation; psychotherapy; evidence-based treatments; neuroplasticity; multimodal approach; personalized interventions

(This special issue belongs to the Section Psychiatric Diseases)

Innovative Approaches and Clinical Insights in Vertigo

edited by Paola Di Mauro

submission deadline 15 Apr 2025 | Viewed by 128 | Submission Open

Keywords: dizziness; vertigo; vestibular system; peripheral and central vertigo; clinical management

(This special issue belongs to the Section Systems Neuroscience)

Chronic Non-infectious Diseases with a High Impact on the Central Nervous System

edited by

Grazyna Lietzau

submission deadline 15 Apr 2025 | Viewed by 92 | Submission Open

Keywords: mental disorders; metabolic diseases; migraine; movement disorders; multiple sclerosis; neurodegenerative diseases; stroke

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

The Use of the Brain–Computer Interface (BCI) in Neuroscience

edited by Yasue Mitsukura

submission deadline 15 Apr 2025 | Viewed by 72 | Submission Open

Keywords: brain-computer interface; human– machine interactions; artificial intelligence; neuroscience

(This special issue belongs to the Section Computational Neuroscience and Neuroinformatics)

HIV-Associated Neurological Diseases

edited by April Thames

submission deadline 15 Apr 2025 | Viewed by 71 | Submission Open

Keywords: HIV; aging; cerebrovascular disease; cultural factors; lifetime stress

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

The Use of Robotics and Artificial Intelligence in Neurorehabilitation: From Diagnosis to Treatment

edited by

Rocco Salvatore Calabrò

David Perpetuini

and

Irene Aprile

submission deadline 18 Apr 2025 | 3 articles | Viewed by 6900 | Submission Open

Keywords: robotic-assisted rehabilitation; machine learning; neurological disorders; artificial intelligence

(This special issue belongs to the Section Neurorehabilitation)

Impact of Stress and Traumatic Events on Youth and Families

edited by Rachel E. Siciliano and Marta Korom

submission deadline 25 Apr 2025 | Viewed by 97 | Submission Open

Keywords: stress; trauma; neuroimaging; psychophysiology; translational; family; development; brain development

(This special issue belongs to the Section Developmental Neuroscience)

New Studies on Stroke Care and Rehabilitation

edited by Rosa Grazia Bellomo and Raoul Saggini

submission deadline 25 Apr 2025 | Viewed by 22 | Submission Open

Keywords: stroke; rehabilitation; neuro-motor rehabilitation; restoring the motor skills of the lower limb; biofeedback; brain injuries; neuroplasticity; neurology

(This special issue belongs to the Section Neurorehabilitation)

Exercise, Nutrition and the Brain

edited by

Marco La Marra

submission deadline 25 Apr 2025 | Viewed by 13 | Submission Open

Keywords: brain health; neuroplasticity; neurodegenerative diseases; physical activity; dietary interventions; nutrients and cognition; mental health; preventive strategies; cognitive performance

(This special issue belongs to the Section Nutritional Neuroscience)

CNS Developmental Issues (DOHAD Concept) Associated with Exposure to Pollutants during Gestation, Lactation/Infancy or Adolescence

edited by Alex Manhães

submission deadline 30 Apr 2025 | 1 articles | Viewed by 671 | Submission Open

Keywords: nervous system; development; pollution; microplastics and nanoplastics; bisphenol; pesticides; PFAS/PFOS; petrochemicals

(This special issue belongs to the Section Environmental Neuroscience)

Retinal Neurochemistry and Development

edited by Roberto Paes-de-Carvalho and Sriparna Majumdar

submission deadline 30 Apr 2025 | Viewed by 314 | Submission Open

Keywords: retina; neurochemistry; development; neurotransmitter; signaling pathways; cultures; neuron– glia interactions; synapses; neuronal differentiation; neuritogenesis

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Brain Metastases: Updates and Future Directions

edited by Aristotelis Kalyvas and Enrique Gutierrez-Valencia

submission deadline 30 Apr 2025 | Viewed by 273 | Submission Open

Keywords: brain metastases; targeted therapy; immunotherapy; artificial intelligence; neurosurgery; radiosurgery; biomarkers

(This special issue belongs to the Section Neuro-oncology)

The Effects of Adverse Childhood Experiences on Emotional and Mental Health

edited by Carmen Alvarez

submission deadline 30 Apr 2025 | Viewed by 108 | Submission Open

Keywords: adverse childhood experiences; emotional health; mental health; stress regulation; brain health

(This special issue belongs to the Section Psychiatric Diseases)

Molecular Mechanisms and Biomarkers of Substance Use Disorders

edited by Ming-Fen Ho

submission deadline 30 Apr 2025 | Viewed by 32 | Submission Open

Keywords: substance use disorders; biomarkers; multi-omics; molecular mechanisms; precision medicine

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Diagnosis and Treatment of Post-stroke and Progressive Aphasias

edited by Sladjana Lukic

submission deadline 1 May 2025 | Viewed by 102 | Submission Open

Keywords: post-stroke aphasia; primary progressive aphasia; lesion– symptom mapping; speech and language; neural markers

(This special issue belongs to the Section Neurolinguistics)

Advances in Non-Invasive Brain Stimulation

edited by

Giuseppe Lanza

and Mariagiovanna Cantone

submission deadline 1 May 2025 | Viewed by 13 | Submission Open

Keywords: translational neuroscience; clinical neurophysiology; neurodegeneration; neural plasticity; neurosonology; sleep disorders; cognitive decline; non-invasive brain stimulation; nutraceuticals; neurogenetics; transcranial magnetic stimulation; dementia; vascular cognitive impairment; stroke; depression; metaplasticity; motor cortex; motor learning; neurotrophins; transcranial-focused ultrasound

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Advanced Clinical Diagnosis, Evaluation, and Treatment of Psychosis

edited by Giulia Menculini and

Gaia Sampogna

submission deadline 5 May 2025 | Viewed by 9 | Submission Open

Keywords: psychotic disorders; affective psychoses; schizophrenia; antipsychotic drugs; psychosocial treatments; at-risk mental states; biomarkers; early intervention; prevention; social psychiatry

(This special issue belongs to the Section Psychiatric Diseases)

Non-invasive Brain Stimulation in Neurological Diseases and Neurorehabilitation

edited by

Maryam Zoghi

submission deadline 15 May 2025 | Viewed by 75 | Submission Open

Keywords: non-invasive brain stimulation; transcranial direct-current stimulation; transcranial magnetic stimulation; neurorehabilitation; neurological diseases; stroke; Parkinson's disease; multiple sclerosis; chronic pain

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Current Perspectives on the Management of Acute-Phase Ischemic Stroke

edited by Stefano Caproni, Ettore Nicolini and Soffien Ajmi

submission deadline 16 May 2025 | Viewed by 176 | Submission Open

Keywords: acute ischemic stroke; endovascular thrombectomy; thrombolysis; clinical treatment

(This special issue belongs to the Section Neurorehabilitation)

Anosognosia

edited by

Guido Gainotti

submission deadline 25 May 2025 | Viewed by 160 | Submission Open

Keywords: anosognosia; disease unawareness; stroke patients; Alzheimer’ s disease; self-awareness; hemiplegia; unilateral neglect; Anton syndrome; insight

(This special issue belongs to the Section Neuropsychology)

Neuromodulation and Neurostimulation in Psychiatric Disorders

edited by

Takuma Inagawa

submission deadline 25 May 2025 | Viewed by 45 | Submission Open

Keywords: brain stimulation; rTMS; ECT; depression; OCD

(This special issue belongs to the Section Psychiatric Diseases)

Diagnosis, Treatment, and Prognosis of Neuromuscular Disorders

edited by

Vincenzo Di Stefano

and

Claudia Vinciguerra

submission deadline 30 May 2025 | 1 articles | Viewed by 1264 | Submission Open

Keywords: neuromuscular disorders; neurogenetics; neuroimmunology; polyneuropathy; myopathy; neuromuscular junction disease; diagnosis; prognosis; treatment; rehabilitation

(This special issue belongs to the Section Neuromuscular and Movement Disorders)

Novel Neuroimaging of Neurological and Psychiatric Disorders

edited by

Darrin J. Lee

submission deadline 30 May 2025 | Viewed by 63 | Submission Open

Keywords: neuroimaging; diagnosis; treatment; psychiatric diseases; brain structure

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Brain Tumors: From Molecular Basis to Therapy

edited by Paolo Tini and Giuseppe Minniti

submission deadline 31 May 2025 | 1 articles | Viewed by 793 | Submission Open

Keywords: brain tumors; molecular pathways; targeted therapy; diagnostic biomarkers; predictive biomarkers; therapeutic resistance

(This special issue belongs to the Section Neuro-oncology)

Interoception and Women’s Health

edited by

Jennifer Todd

and Jennifer Murphy

submission deadline 31 May 2025 | Viewed by 658 | Submission Open

Keywords: interoception; women’ s health; sex differences; healthcare disparities; reproductive health

(This special issue belongs to the Section Neuropsychology)

Relationships between Disordered Sleep and Mental Health

edited by Anne M. Fink

submission deadline 31 May 2025 | 1 articles | Viewed by 623 | Submission Open

Keywords: circadian rhythms; depression; genetics and genomics; rapid eye movement sleep behavior disorder; schizophrenia; sleep deprivation; shift– work sleep disorder; substance use disorder; suicide

(This special issue belongs to the Section Psychiatric Diseases)

Understanding the Functioning of Brain Networks in Health and Disease

edited by

Moses O. Sokunbi

submission deadline 31 May 2025 | Viewed by 30 | Submission Open

Keywords: brain networks; cognitive dysfunction; diffusion tensor imaging (DTI); electroencephalography (EEG); functional connectivity; functional magnetic resonance imaging (fMRI); magnetoencephalography (MEG); neurological disorders; neuroplasticity; psychiatric disorders; artificial intelligence; deep learning; neural networks; signal complexity

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

State-of-the-Art in Multisensory Integration: Predicting Age-Related Clinical Outcomes

edited by Jeannette R. Mahoney

submission deadline 1 Jun 2025 | Viewed by 80 | Submission Open

Keywords: multisensory integration; sensorimotor integration; aging; mobility; balance; falls; cognition; dementia

(This special issue belongs to the Section Sensory and Motor Neuroscience)

The Use of Chemogenetics and Optogenetics on Understanding the Neurobiology of Brain Disorders

edited by

Sandesh Panthi

and

Marc Ekker

submission deadline 6 Jun 2025 | Viewed by 474 | Submission Open

Keywords: chemogenetics; optogenetics; DREADDs; brain disorders; neurobiology of disease

Exploration of the Brain Structural Changes in Patients with Mental Illness

edited by

Fengyu Zhang

submission deadline 15 Jun 2025 | Viewed by 20 | Submission Open

Keywords: psychiatric diseases; human brain connectome; biomarkers; endophenotypes

(This special issue belongs to the Section Psychiatric Diseases)

Neurofunctional Basis of Language Processing—2nd Edition

edited by

Roozbeh Rezaie

and

Vahab Youssof Zadeh

submission deadline 20 Jun 2025 | Viewed by 21 | Submission Open

Keywords: language neurological disorders; non-invasive; brain mapping; neural networks; plasticity

(This special issue belongs to the Section Neurolinguistics)

Multisensory Perception of the Body and Its Movement

edited by Monica Gori, Lara Coelho and Silvia Zanchi

submission deadline 27 Jun 2025 | Viewed by 22 | Submission Open

Keywords: body; space; spatial navigation; development; blindness multisensory

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Integrating Advanced Imaging Techniques and Computational Models in Headache Research

edited by Catherine S. Hubbard

submission deadline 28 Jun 2025 | Viewed by 7 | Submission Open

Keywords: personalized medicine; migraine; headache disorders; machine learning; deep learning; neuroimaging; animal models; neuromodulation; fMRI; neural networks

(This special issue belongs to the Section Neuroscience of Pain)

New Advances in Neuroimmunology and Neuroinflammation

edited by

Junhui Wang

Xueping Chen

, Jing Sun and Matheus Uba Chupel

submission deadline 30 Jun 2025 | 1 articles | Viewed by 808 | Submission Open

Keywords: neuroinflammation; neuroimmunology; glia; neurodegenerative diseases; cytokines; chemokines

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Recent Advances in Neuroscience: Theoretical, Applied, and Experimental Research

edited by

Julian Keenan

submission deadline 30 Jun 2025 | Viewed by 178 | Submission Open

Keywords: neuroscience; genetics; brain; optogenetics; fMRI; MRI; TMS; tDCS; gene therapy; evolutionary neuroscience; psychiatric disorders

(This special issue belongs to the Section Systems Neuroscience)

Minimally Invasive Surgery for Brain and Skull Base Tumors

edited by

Carmine Antonio Donofrio

submission deadline 30 Jun 2025 | Viewed by 121 | Submission Open

Keywords: minimally invasive surgery; keyhole approaches; endoscopic surgery; stereotactic surgery; parafascicular surgery; brain tumors; neuro-oncology; skull base tumors

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

The Role of Awareness in Visuomotor Control, Perception, and Spatial Attention

edited by

and

submission deadline 30 Jun 2025 | Viewed by 103 | Submission Open

Keywords: visual awareness; visual perception; action; visuospatial attention; visuomotor integration

(This special issue belongs to the Section Behavioral Neuroscience)

Pain Memory: Assessment and Clinical Implications

edited by

Ferran Cuenca-Martínez

and

Núria Sempere-Rubio

submission deadline 30 Jun 2025 | Viewed by 62 | Submission Open

Keywords: pain memory; psychosocial; pain chronification; pain medicine; pain assessment; pain neuroscience

(This special issue belongs to the Section Neuroscience of Pain)

Clinical Research on Sleep Disorders: Opportunities and Challenges

edited by

Pasquale Tondo

submission deadline 30 Jun 2025 | Viewed by 50 | Submission Open

Keywords: innovation; personalized management; sleep disorders; telemonitoring; treatment

(This special issue belongs to the Section Sleep and Circadian Neuroscience)

Psychological Approaches to the Understanding and Treatment of Psychological Difficulties in Individuals with Neurodegenerative Diseases

edited by

Nicolò Zarotti

submission deadline 15 Jul 2025 | Viewed by 215 | Submission Open

Keywords: psychotherapy; psychological interventions; emotional distress; behavioural difficulties; neurodegenerative diseases; dementia; Huntington’ s disease; Parkinson’ s disease; motor neuron disease; amyotrophic lateral sclerosis

(This special issue belongs to the Section Behavioral Neuroscience)

Trends in Spinal Muscular Atrophy and Duchenne Muscular Dystrophy

edited by Alberto Dubrovsky

submission deadline 15 Jul 2025 | Viewed by 69 | Submission Open

Keywords: spinal muscular atrophy (SMA); Duchenne muscular dystrophy (DMD); neuromuscular disorders; therapies; new drugs

(This special issue belongs to the Section Neuromuscular and Movement Disorders)

Advances in Biomedical Research and Clinical Studies of Parkinson’s Disease and Atypical Parkinsonian Disorders

edited by

Frank C. Church

and Stefania Brotini

submission deadline 25 Jul 2025 | Viewed by 67 | Submission Open

Keywords: neurodegenerative diseases; Parkinson’ s disease (PD); atypical parkinsonian disorders (APDs); Alzheimer’ s disease (AD); frontotemporal dementia (FTD); Dementia with Lewy Body (DLB); Multiple System Atrophy Parkinsonian Variant (MSA-P); Progressive Supranuclear Palsy (PSP); Corticobasal Degeneration (CBD); biomarkers of PD and APD; pathophysiology of neurodegeneration in PD and APD; α -synuclein; beta-amyloid; and tau; role of exercise in therapy for neurodegenerative disorders (PD and APD); recent discoveries in the genetics and therapies of neurodegenerative dementias in PD and APD; brain plasticity; Complementary & Alternative Medicine (CAM) approaches in PD and APD; research aimed to understand the role of neuroinflammation in PD and APD; advances in the role of a dysfunctional immune system in the etiology of PD and APD; mitochondria and cellular energy problems in PD and APD.

(This special issue belongs to the Section Neurodegenerative Diseases)

The Impact of Stroke on Functional Cognition and Rehabilitation Approaches

edited by Glen Gillen

submission deadline 31 Jul 2025 | Viewed by 367 | Submission Open

Keywords: cerebrovascular accident; stroke; cognition; activities of daily living; quality of life; assessment; intervention

(This special issue belongs to the Section Neurorehabilitation)

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