Neoadjuvant Immunotherapy in Genitourinary Tumors
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Immunology and Immunotherapy".
Deadline for manuscript submissions: closed (20 October 2024) | Viewed by 521
Special Issue Editors
Interests: urology; uro-oncology; andrology; kidney stones; urolithiasis; incontinence; CEUS; contrast-enhanced ultrasound; kidney cancer; bladder cancer; prostate cancer; penile cancer; reflux
2. Department of Biomedical Sciences, Humanitas University, 20072 Pieve Emanuele, Italy
Interests: uro-oncology
2. Department of Medical Biotechnology, University of Siena, 53100 Siena, Italy
Interests: cell cycle dependent kinase (CDK); retinoblastoma protein family; cancer therapy; mesothelioma; CDK9; Rb2
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Special Issue Information
Dear Colleagues,
Genitourinary (GU) malignancies affect many people worldwide, with millions of new cases diagnosed annually. In recent decades, our understanding of cancer and its pathophysiology has evolved. It has been well established that cancer cells have developed multiple mechanisms to avoid the immune system.
The use of immunotherapy in the preoperative or neoadjuvant setting is supported by preclinical studies showing that stronger and broader immune responses can be generated when immunotherapy is administered with the primary tumor and/or regional lymph nodes intact. By interfering with pathways in the tumor microenvironment, immune checkpoint inhibitors (ICIs) allow the immune system to “ramp up” and effectively target malignant cells.
This Special Issue delves into the role of immunotherapy in the treatment of GU malignancies, specifically urothelial, renal, prostate, and other rarer tumors. The goal is to enhance “precision therapy” evidence to increase overall survival and progression-free survival.
Dr. Antonio Tufano
Dr. Nadia Cordua
Prof. Dr. Antonio Giordano
Guest Editors
Manuscript Submission Information
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Keywords
- immunotherapy
- immune checkpoint inhibitor
- bladder cancer
- urothelial cancer
- kidney cancer
- renal cell carcinoma
- prostate cancer
- testicular cancer
- penile cancer
- adrenocortical carcinoma
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