Search Results (5)

Poultry production is accompanied by the use of antimicrobial agents because no production step is free of microorganisms. In the absence of antimicrobial treatments with synthetic drugs, essential oils are among the most cited natural alternatives used to prevent and treat microbial contamination in poultry. Although there are several studies on the antimicrobial properties of essential oils, there is still no review that simultaneously compiles information on the leading antimicrobial role of essential oils from Citrus aurantifolia (CAEO), Ocimum basilicum (OBEO), and Allium sativum (ASEO) in poultry. Awareness of the antimicrobial role of these substances opens the door to encouraging their use in natural antimicrobial protocols and discouraging harmful synthetics in poultry. This review aimed to compile information on applying CAEO, OBEO, and ASEO as antimicrobials in poultry farming. The available literature suggests that these essential oils can proportionately align with the poultry industry’s demands for microbiologically safe food products. Full article

Human tegumentary leishmaniasis (HTL) is a serious tropical disease caused by Leishmania amazonensis. Developing new leishmanicidal agents can help overcome current treatment challenges, such as drug resistance and toxicity. Essential oils are a source of lipophilic substances with diverse therapeutic properties. This study aimed to determine the anti-L. amazonensis activity, cytotoxicity, and chemical profile of Allium sativum essential oil (ASEO). The effect of ASEO on parasite and mammalian cells viability was evaluated using resazurin and MTT assays, respectively. The oil’s effect against intracellular amastigotes was also determined. Transmission electron microscopy was used to assess the ultrastructural changes induced by ASEO. In addition, the chemical constituents of ASEO were identified by gas chromatography-mass spectrometry (GC-MS). The cytotoxic potential was evaluated in vitro and in silico. The oil displayed IC₅₀ of 1.76, 3.46, and 3.77 µg/mL against promastigotes, axenic, and intracellular amastigotes, respectively. Photomicrographs of treated parasites showed plasma membrane disruption, increased lipid bodies, and autophagic-like structures. ASEO chemical profiling revealed 1,2,4,6-tetrathiepane (24.84%) and diallyl disulfide (16.75%) as major components. Computational pharmacokinetics and toxicological analysis of ASEO’s major components demonstrated good oral bioavailability and better toxicological endpoints than the reference drugs. Altogether, the results suggest that ASEO could be an alternative drug candidate against HTL. Full article

The visibility of academic articles or conference papers depends on their being easily found in academic search engines, above all in Google Scholar. To enhance this visibility, search engine optimization (SEO) has been applied in recent years to academic search engines in order to optimize documents and, thereby, ensure they are better ranked in search pages (i.e., academic search engine optimization or ASEO). To achieve this degree of optimization, we first need to further our understanding of Google Scholar’s relevance ranking algorithm, so that, based on this knowledge, we can highlight or improve those characteristics that academic documents already present and which are taken into account by the algorithm. This study seeks to advance our knowledge in this line of research by determining whether the language in which a document is published is a positioning factor in the Google Scholar relevance ranking algorithm. Here, we employ a reverse engineering research methodology based on a statistical analysis that uses Spearman’s correlation coefficient. The results obtained point to a bias in multilingual searches conducted in Google Scholar with documents published in languages other than in English being systematically relegated to positions that make them virtually invisible. This finding has important repercussions, both for conducting searches and for optimizing positioning in Google Scholar, being especially critical for articles on subjects that are expressed in the same way in English and other languages, the case, for example, of trademarks, chemical compounds, industrial products, acronyms, drugs, diseases, etc. Full article

The effects of different factors—such as age, sex, performance level, and athletic shoe features—on postural balance in athletes remain unclear. The main objective of our study is to identify the features of postural stability in athletes of different age, sex, performance level, and using different types of athletic shoes. This study assessed postural stability in athletes (n = 936, 6–47 years) in a normal bipedal stance with eyes open (EO) and eyes closed (EC). Postural stability was evaluated based on the center of pressure (COP), sway area (AS), and velocity (VCP) while standing on a stabiloplatform. Children (6–12 years) and teen athletes (13–17 years) showed reduced AS-EO (p < 0.01) and VCP-EO (p < 0.01) compared to control (n = 225, 7–30 years). In male and female athletes aged 18+, only VCP-EC was lower versus control. In females (13–17 and 18+), VCP-EO and EC were lower than in males (p < 0.05). Only in the Shooting group, the athletes’ performance levels had an effect on VCP-EO (p = 0.020). Long use of rigid athletic shoes with stiff ankle support was associated with reduced posture stability. Postural stability in athletes was mostly influenced by the athlete‘s age, and, to a lesser extent, by their sex, performance level, and athlete shoe features. Full article

Search engine optimization (SEO) constitutes the set of methods designed to increase the visibility of, and the number of visits to, a web page by means of its ranking on the search engine results pages. Recently, SEO has also been applied to academic databases and search engines, in a trend that is in constant growth. This new approach, known as academic SEO (ASEO), has generated a field of study with considerable future growth potential due to the impact of open science. The study reported here forms part of this new field of analysis. The ranking of results is a key aspect in any information system since it determines the way in which these results are presented to the user. The aim of this study is to analyze and compare the relevance ranking algorithms employed by various academic platforms to identify the importance of citations received in their algorithms. Specifically, we analyze two search engines and two bibliographic databases: Google Scholar and Microsoft Academic, on the one hand, and Web of Science and Scopus, on the other. A reverse engineering methodology is employed based on the statistical analysis of Spearman’s correlation coefficients. The results indicate that the ranking algorithms used by Google Scholar and Microsoft are the two that are most heavily influenced by citations received. Indeed, citation counts are clearly the main SEO factor in these academic search engines. An unexpected finding is that, at certain points in time, Web of Science (WoS) used citations received as a key ranking factor, despite the fact that WoS support documents claim this factor does not intervene. Full article