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Search Results (906)

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Keywords = hazard identification

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15 pages, 10388 KiB  
Article
Shear Thickening Fluid and Sponge-Hybrid Triboelectric Nanogenerator for a Motion Sensor Array-Based Lying State Detection System
by Youngsu Kim, Inkyum Kim, Maesoon Im and Daewon Kim
Materials 2024, 17(14), 3536; https://doi.org/10.3390/ma17143536 (registering DOI) - 17 Jul 2024
Viewed by 125
Abstract
Issues of size and power consumption in IoT devices can be addressed through triboelectricity-driven energy harvesting technology, which generates electrical signals without external power sources or batteries. This technology significantly reduces the complexity of devices, enhances installation flexibility, and minimizes power consumption. By [...] Read more.
Issues of size and power consumption in IoT devices can be addressed through triboelectricity-driven energy harvesting technology, which generates electrical signals without external power sources or batteries. This technology significantly reduces the complexity of devices, enhances installation flexibility, and minimizes power consumption. By utilizing shear thickening fluid (STF), which exhibits variable viscosity upon external impact, the sensitivity of triboelectric nanogenerator (TENG)-based sensors can be adjusted. For this study, the highest electrical outputs of STF and sponge-hybrid TENG (SSH-TENG) devices under various input forces and frequencies were generated with an open-circuit voltage (VOC) of 98 V and a short-circuit current (ISC) of 4.5 µA. The maximum power density was confirmed to be 0.853 mW/m2 at a load resistance of 30 MΩ. Additionally, a lying state detection system for use in medical settings was implemented using SSH-TENG as a hybrid triboelectric motion sensor (HTMS). Each unit of a 3 × 2 HTMS array, connected to a half-wave rectifier and 1 MΩ parallel resistor, was interfaced with an MCU. Real-time detection of the patient’s condition through the HTMS array could enable the early identification of hazardous situations and alerts. The proposed HTMS continuously monitors the patient’s movements, promptly identifying areas prone to pressure ulcers, thus effectively contributing to pressure ulcer prevention. Full article
(This article belongs to the Special Issue Nanoarchitectonics in Materials Science)
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21 pages, 11344 KiB  
Article
Orbital-Rail-Type Automatic Inspection Device for Pipeline Welds Using Radiation Dose Prediction Results from FLUKA Simulation
by Du-Song Kim, Sung-Hoe Heo, Seung-Uk Heo and Jaewoong Kim
Appl. Sci. 2024, 14(14), 6165; https://doi.org/10.3390/app14146165 - 15 Jul 2024
Viewed by 350
Abstract
Pipeline welds typically do not have secondary reinforcement, rendering welds highly vulnerable to leakage accidents caused by the movement of gases or liquids. Therefore, identifying internal defects in welds through radiographic testing (RT) is critical for a visual and quantitative evaluation of weld [...] Read more.
Pipeline welds typically do not have secondary reinforcement, rendering welds highly vulnerable to leakage accidents caused by the movement of gases or liquids. Therefore, identifying internal defects in welds through radiographic testing (RT) is critical for a visual and quantitative evaluation of weld defects. In this study, we developed a device that can automatically inspect the circumferential connection between pipes by applying a digital radiography testing (DRT) technique that can convert radiation signals into real-time electrical signals by using a digital detector array (DDA). Gamma rays were used to minimize spatial constraints in the inspection environment and optimization was performed to satisfy quality requirements set by international standards. Furthermore, FLUKA simulation was performed to predict radiation intensity for accurate radiation leakage identification to enable the shielding design to be supplemented with lead rubber. This measure considerably reduces the safe distance for radiation leakage during field testing. The results confirmed the feasibility of a novel automated inspection technique that integrates automatic inspection devices and ensures safety using radiation, the byproduct of which is a hazardous material. Full article
(This article belongs to the Special Issue Advances and Applications of Nondestructive Testing)
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20 pages, 7894 KiB  
Article
Hazardous High-Energy Seismic Event Discrimination Method Based on Region Division and Identification of Main Impact Factors: A Case Study
by Yaoqi Liu, Anye Cao, Qiang Wang, Geng Li, Xu Yang and Changbin Wang
Appl. Sci. 2024, 14(14), 6154; https://doi.org/10.3390/app14146154 - 15 Jul 2024
Viewed by 340
Abstract
An investigation of risk factors has been identified as a crucial aspect of the routine management of rockburst. However, the identification methods for principal impact factors and the examination of the relationship between seismic energy and other source parameters have not been extensively [...] Read more.
An investigation of risk factors has been identified as a crucial aspect of the routine management of rockburst. However, the identification methods for principal impact factors and the examination of the relationship between seismic energy and other source parameters have not been extensively explored to conduct dynamic risk management. This study aims to quantify impact risk factors and discriminate hazardous high-energy seismic events. The analytic hierarchy process (AHP) and entropy weight method (EWM) are utilized to ascertain the primary control factors based on geotechnical data and nearly two months of seismic data from a longwall panel. Furthermore, the distribution law and correlation relationship among seismic source parameters are systematically analyzed. Results show that the effect of coal depth, coal seam thickness, coal dip, and mining speed covers the entire mining process, while the fault is only prominent in localized areas. There are varying degrees of log-positive correlations between seismic energy and other source parameters, and this positive correlation is more pronounced for hazardous high-energy seismic events. Utilizing the linear logarithmic relationship between seismic energy and other source parameters, along with the impact weights of dynamic risks, the comprehensive energy index for evaluating high-energy seismic events is proposed. The comprehensive energy index identification method proves to be more accurate by comparing with the high-energy seismic events based on energy criteria. The limitations and improvements of this method are also synthesized to obtaining a wide range of applications. Full article
(This article belongs to the Special Issue Mining Safety: Challenges and Prevention, 2nd Edition)
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19 pages, 15351 KiB  
Article
A Deep-Learning-Based Algorithm for Landslide Detection over Wide Areas Using InSAR Images Considering Topographic Features
by Ning Li, Guangcai Feng, Yinggang Zhao, Zhiqiang Xiong, Lijia He, Xiuhua Wang, Wenxin Wang and Qi An
Sensors 2024, 24(14), 4583; https://doi.org/10.3390/s24144583 - 15 Jul 2024
Viewed by 232
Abstract
The joint action of human activities and environmental changes contributes to the frequent occurrence of landslide, causing major hazards. Using Interferometric Synthetic Aperture Radar (InSAR) technique enables the detailed detection of surface deformation, facilitating early landslide detection. The growing availability of SAR data [...] Read more.
The joint action of human activities and environmental changes contributes to the frequent occurrence of landslide, causing major hazards. Using Interferometric Synthetic Aperture Radar (InSAR) technique enables the detailed detection of surface deformation, facilitating early landslide detection. The growing availability of SAR data and the development of artificial intelligence have spurred the integration of deep learning methods with InSAR for intelligent geological identification. However, existing studies using deep learning methods to detect landslides in InSAR deformation often rely on single InSAR data, which leads to the presence of other types of geological hazards in the identification results and limits the accuracy of landslide identification. Landslides are affected by many factors, especially topographic features. To enhance the accuracy of landslide identification, this study improves the existing geological hazard detection model and proposes a multi-source data fusion network termed MSFD-Net. MSFD-Net employs a pseudo-Siamese network without weight sharing, enabling the extraction of texture features from the wrapped deformation data and topographic features from topographic data, which are then fused in higher-level feature layers. We conducted comparative experiments on different networks and ablation experiments, and the results show that the proposed method achieved the best performance. We applied our method to the middle and upper reaches of the Yellow River in eastern Qinghai Province, China, and obtained deformation rates using Sentinel-1 SAR data from 2018 to 2020 in the region, ultimately identifying 254 landslides. Quantitative evaluations reveal that most detected landslides in the study area occurred at an elevation of 2500–3700 m with slope angles of 10–30°. The proposed landslide detection algorithm holds significant promise for quickly and accurately detecting wide-area landslides, facilitating timely preventive and control measures. Full article
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16 pages, 9604 KiB  
Article
Travel Characteristics and Vulnerability Analysis of Road Resource Utilization Based on Taxi GPS Data
by Wei Zhang, Duanqiang Zhai and Ziqi Wang
Sustainability 2024, 16(14), 5979; https://doi.org/10.3390/su16145979 - 12 Jul 2024
Viewed by 372
Abstract
Residents’ travel and logistics are greatly affected by urban transportation networks, which are one of the most important supports for urban socio-economic activities. Urban transportation systems tend to cripple when faced with challenges such as natural hazards and social unrest. This paper proposes [...] Read more.
Residents’ travel and logistics are greatly affected by urban transportation networks, which are one of the most important supports for urban socio-economic activities. Urban transportation systems tend to cripple when faced with challenges such as natural hazards and social unrest. This paper proposes a framework for a vulnerability analysis of urban road networks (URNs) based on real traffic flows with GPS data. An improved K-shell critical node identification method is proposed based on structural and traffic characteristics. Then, a cascade failure model is proposed to analyze the structural and functional vulnerability of the URN by combining the load capacity model and the vulnerability model. This paper takes the Harbin main city URN as an example and first analyzes the passenger travel distribution and the relationship between travel orders, population and POI. Four deliberate attack methods are proposed to analyze the vulnerability of the URN under deliberate attack on commute days and rest days. The experimental results show that URNs exhibit intense vulnerability, with the fastest cascading failure occurring based on improved K-shell node failure. Furthermore, URNs are more vulnerable on rest days compared to commuter days. These findings could be used to inform a vulnerability-based spatiotemporal design of UBNs and provide theoretical support for managing traffic congestion on different days. Full article
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26 pages, 11752 KiB  
Article
Overflow Identification and Early Warning of Managed Pressure Drilling Based on Series Fusion Data-Driven Model
by Wei Liu, Jiasheng Fu, Song Deng, Pengpeng Huang, Yi Zou, Yadong Shi and Chuchu Cai
Processes 2024, 12(7), 1436; https://doi.org/10.3390/pr12071436 - 9 Jul 2024
Viewed by 379
Abstract
Overflow is one of the complicated working conditions that often occur in the drilling process. If it is not discovered and controlled in time, it will cause gas invasion, kick, and blowout, which will bring inestimable accidents and hazards. Therefore, overflow identification and [...] Read more.
Overflow is one of the complicated working conditions that often occur in the drilling process. If it is not discovered and controlled in time, it will cause gas invasion, kick, and blowout, which will bring inestimable accidents and hazards. Therefore, overflow identification and early warning has become a hot spot and a difficult problem in drilling engineering. In the face of the limitations and lag of traditional overflow identification methods, the poor application effect, and the weak mechanisms of existing models and methods, a method of series fusion of feature data obtained from physical models as well as sliding window and random forest machine learning algorithm models is proposed. The overflow identification and early warning model of managed pressure drilling based on a series fusion data-driven model is established. The research results show that the series fusion data-driven model in this paper is superior to the overflow identification effect of other feature data and algorithm models, and the overflow recognition accuracy on the test samples reaches more than 99%. In addition, when the overflow is identified, the overflow warning is performed through the pop-up window and feature information output. The research content provides guidance for the identification of drilling overflow and the method of model fusion. Full article
(This article belongs to the Section Automation Control Systems)
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17 pages, 6547 KiB  
Article
Development and Application of IoT Monitoring Systems for Typical Large Amusement Facilities
by Zhao Zhao, Weike Song, Huajie Wang, Yifeng Sun and Haifeng Luo
Sensors 2024, 24(14), 4433; https://doi.org/10.3390/s24144433 - 9 Jul 2024
Viewed by 277
Abstract
The advent of internet of things (IoT) technology has ushered in a new dawn for the digital realm, offering innovative avenues for real-time surveillance and assessment of the operational conditions of intricate mechanical systems. Nowadays, mechanical system monitoring technologies are extensively utilized in [...] Read more.
The advent of internet of things (IoT) technology has ushered in a new dawn for the digital realm, offering innovative avenues for real-time surveillance and assessment of the operational conditions of intricate mechanical systems. Nowadays, mechanical system monitoring technologies are extensively utilized in various sectors, such as rotating and reciprocating machinery, expansive bridges, and intricate aircraft. Nevertheless, in comparison to standard mechanical frameworks, large amusement facilities, which constitute the primary manned electromechanical installations in amusement parks and scenic locales, showcase a myriad of structural designs and multiple failure patterns. The predominant method for fault diagnosis still relies on offline manual evaluations and intermittent testing of vital elements. This practice heavily depends on the inspectors’ expertise and proficiency for effective detection. Moreover, periodic inspections cannot provide immediate feedback on the safety status of crucial components, they lack preemptive warnings for potential malfunctions, and fail to elevate safety measures during equipment operation. Hence, developing an equipment monitoring system grounded in IoT technology and sensor networks is paramount, especially considering the structural nuances and risk profiles of large amusement facilities. This study aims to develop customized operational status monitoring sensors and an IoT platform for large roller coasters, encompassing the design and fabrication of sensors and IoT platforms and data acquisition and processing. The ultimate objective is to enable timely warnings when monitoring signals deviate from normal ranges or violate relevant standards, thereby facilitating the prompt identification of potential safety hazards and equipment faults. Full article
(This article belongs to the Section Internet of Things)
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12 pages, 5336 KiB  
Article
Tracing Soil Contamination from Pre-Roman Slags at the Monte Romero Archaeological Site, Southwest Spain
by Juan Carlos Fernández-Caliani and Juan Aurelio Pérez-Macías
Soil Syst. 2024, 8(3), 78; https://doi.org/10.3390/soilsystems8030078 - 8 Jul 2024
Viewed by 544
Abstract
Soil serves as a repository of human history, preserving artifacts within its horizons. However, the presence of chemically reactive remnants, such as ancient slags, can significantly impact the surrounding soil environment. This paper addresses this scarcely explored issue by focusing on soil contamination [...] Read more.
Soil serves as a repository of human history, preserving artifacts within its horizons. However, the presence of chemically reactive remnants, such as ancient slags, can significantly impact the surrounding soil environment. This paper addresses this scarcely explored issue by focusing on soil contamination arising from pre-Roman slag deposits at the Monte Romero archaeological site in southwest Spain, dating back to the Tartessian period (c. 7th century BC). Through the high-resolution microscopy examination of slag wastes and the trace element analysis of soil samples by ICP-OES, this study evaluated current contamination status using a multi-index approach. The results revealed markedly high levels of Pb (>5000 mg kg−1), Cu (up to 2730 mg kg−1), and As (up to 445 mg kg−1) in the soil compared to a control sample. The identification of secondary complex compounds like Cu arsenates and Pb arsenates/antimonates within slag cavities suggests post-depositional weathering processes, leading to the dispersion of potentially toxic elements into the surrounding soil. Assessments through indices of contamination and potential ecological risk highlighted severe contamination, particularly concerning Ag, Pb, Sb, Cu, and As. This study underscores the importance of addressing potential environmental hazards associated with archaeological sites hosting remnants of metal production. Full article
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20 pages, 1217 KiB  
Article
Hazard Identification and Risk Assessment for Sustainable Shipyard Floating Dock Operations: An Integrated Spherical Fuzzy Analytical Hierarchy Process and Fuzzy CoCoSo Approach
by Semra Bayhun and Nihan Çetin Demirel
Sustainability 2024, 16(13), 5790; https://doi.org/10.3390/su16135790 (registering DOI) - 7 Jul 2024
Viewed by 681
Abstract
Background: This study investigated the process of selecting sustainable safety protocols for floating dock operations in shipyards by identifying potential workplace risks in emergency situations. Thirteen occupational hazards for shipyard floating dock operations were identified through a literature review and expert discussions. Methods: [...] Read more.
Background: This study investigated the process of selecting sustainable safety protocols for floating dock operations in shipyards by identifying potential workplace risks in emergency situations. Thirteen occupational hazards for shipyard floating dock operations were identified through a literature review and expert discussions. Methods: We incorporated four risk elements (consequence: C, frequency: F, probability: P, and number of people at risk: NP) from the Fine–Kinney and Hazard Rating Number System (HRNS) approaches as the risk assessment criteria. We obtained the importance weights of the risk assessment criteria via the Spherical Fuzzy Analytical Hierarchy Process (SF-AHP) and extended the Combined Compromise Solution (CoCoSo) method within the fuzzy framework to prioritize occupational hazards. This study demonstrated the practicality and efficiency of the proposed emergency risk assessment model for shipyard floating dock operations through a case example of occupational risk assessment. Results: The analysis results show that H4 is the occupational hazard with the highest priority, with a score of 3.553. H4 represents the hazard associated with insufficient access to the entire pool area. The second and third most important hazards are the inability of cranes to move freely in and out of the berthing dock and the inability to dispatch emergency teams. These hazards, denoted H1 and H12, follow closely behind with scores of 3.391 and 3.344, respectively. H10 is deemed the least concerning hazard, with a score of 1.802. Conclusions: Professionals can handle complex and uncertain risk assessment data more flexibly using the proposed system, which excels in accurately organizing occupational hazards. Full article
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27 pages, 2801 KiB  
Article
Risk Assessment of TBM Construction Based on a Matter-Element Extension Model with Optimized Weight Distribution
by Tao Fu, Kebin Shi, Renyi Shi, Zhipeng Lu and Jianming Zhang
Appl. Sci. 2024, 14(13), 5911; https://doi.org/10.3390/app14135911 - 6 Jul 2024
Viewed by 344
Abstract
In order to effectively address the potential hazards associated with the construction of Phase II of the YE Water Supply Project’s KS tunnel in Xinjiang, this study employs the WBS-RBS (Work Breakdown Structure and Risk Breakdown Structure) method for risk identification. This approach [...] Read more.
In order to effectively address the potential hazards associated with the construction of Phase II of the YE Water Supply Project’s KS tunnel in Xinjiang, this study employs the WBS-RBS (Work Breakdown Structure and Risk Breakdown Structure) method for risk identification. This approach aims to identify various risks that may arise during TBM (Tunnel Boring Machine) construction. To prevent incomplete risk factor identification resulting from subjective judgment, a risk index system is established based on the identification results. Subsequently, a matter-element extension model is utilized to quantify the risk factors within this index system, and comprehensive weights are determined using variable weight theory to assess construction risk levels. Importance analysis of each index is then conducted to identify those with significant impact on risk evaluation outcomes. Finally, by comparing actual engineering cases with other risk evaluation models, this paper verifies the reliability of its constructed risk assessment model and proposes measures for controlling potential risks based on these evaluations. The paper provides a clear definition of safety risks encountered during TBM construction and conducts comprehensive risk assessments as a valuable reference for research related to the tunnel boring machine construction period in tunnel engineering. Full article
(This article belongs to the Special Issue Advances in Failure Mechanism and Numerical Methods for Geomaterials)
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15 pages, 5076 KiB  
Article
Identification and Removal of Pollen Spectral Interference in the Classification of Hazardous Substances Based on Excitation Emission Matrix Fluorescence Spectroscopy
by Pengjie Zhang, Bin Du, Jiwei Xu, Jiang Wang, Zhiwei Liu, Bing Liu, Fanhua Meng and Zhaoyang Tong
Molecules 2024, 29(13), 3132; https://doi.org/10.3390/molecules29133132 - 1 Jul 2024
Viewed by 520
Abstract
Sensitively detecting hazardous and suspected bioaerosols is crucial for safeguarding public health. The potential impact of pollen on identifying bacterial species through fluorescence spectra should not be overlooked. Before the analysis, the spectrum underwent preprocessing steps, including normalization, multivariate scattering correction, and Savitzky–Golay [...] Read more.
Sensitively detecting hazardous and suspected bioaerosols is crucial for safeguarding public health. The potential impact of pollen on identifying bacterial species through fluorescence spectra should not be overlooked. Before the analysis, the spectrum underwent preprocessing steps, including normalization, multivariate scattering correction, and Savitzky–Golay smoothing. Additionally, the spectrum was transformed using difference, standard normal variable, and fast Fourier transform techniques. A random forest algorithm was employed for the classification and identification of 31 different types of samples. The fast Fourier transform improved the classification accuracy of the sample excitation–emission matrix fluorescence spectrum data by 9.2%, resulting in an accuracy of 89.24%. The harmful substances, including Staphylococcus aureus, ricin, beta-bungarotoxin, and Staphylococcal enterotoxin B, were clearly distinguished. The spectral data transformation and classification algorithm effectively eliminated the interference of pollen on other components. Furthermore, a classification and recognition model based on spectral feature transformation was established, demonstrating excellent application potential in detecting hazardous substances and protecting public health. This study provided a solid foundation for the application of rapid detection methods for harmful bioaerosols. Full article
(This article belongs to the Special Issue Machine Learning in Green Chemistry)
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31 pages, 23976 KiB  
Article
GIS-Based Integrated Multi-Hazard Vulnerability Assessment in Makedonska Kamenica Municipality, North Macedonia
by Bojana Aleksova, Ivica Milevski, Slavoljub Dragićević and Tin Lukić
Atmosphere 2024, 15(7), 774; https://doi.org/10.3390/atmos15070774 - 28 Jun 2024
Viewed by 781
Abstract
This study presents a comprehensive analysis of natural hazard susceptibility in the Makedonska Kamenica municipality of North Macedonia, encompassing erosion assessment, landslides, flash floods, and forest fire vulnerability. Employing advanced GIS and remote sensing (RS) methodologies, hazard models were meticulously developed and integrated [...] Read more.
This study presents a comprehensive analysis of natural hazard susceptibility in the Makedonska Kamenica municipality of North Macedonia, encompassing erosion assessment, landslides, flash floods, and forest fire vulnerability. Employing advanced GIS and remote sensing (RS) methodologies, hazard models were meticulously developed and integrated to discern areas facing concurrent vulnerabilities. Findings unveil substantial vulnerabilities prevalent across the area, notably along steep terrain gradients, river valleys, and deforested landscapes. Erosion assessment reveals elevated rates, with a mean erosion coefficient (Z) of 0.61 and an annual erosion production of 182,712.9 m3, equivalent to a specific erosion rate of 961.6 m3/km2/year. Landslide susceptibility analysis identifies 31.8% of the municipality exhibiting a very high probability of landslides, while flash flood susceptibility models depict 3.3% of the area prone to very high flash flood potential. Forest fire susceptibility mapping emphasizes slightly less than one-third of the municipality’s forested area is highly or very highly susceptible to fires. Integration of these hazard models elucidates multi-hazard zones, revealing that 11.0% of the municipality’s territory faces concurrent vulnerabilities from excessive erosion, landslides, flash floods, and forest fires. These zones are predominantly located in upstream areas, valleys of river tributaries, and the estuary region. The identification of multi-hazard zones underscores the critical need for targeted preventive measures and robust land management strategies to mitigate potential disasters and safeguard both human infrastructure and natural ecosystems. Recommendations include the implementation of enhanced monitoring systems, validation methodologies, and community engagement initiatives to bolster hazard preparedness and response capabilities effectively. Full article
(This article belongs to the Section Biosphere/Hydrosphere/Land–Atmosphere Interactions)
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15 pages, 5302 KiB  
Article
Deep Learning-Based Geomorphic Feature Identification in Dredge Pit Marine Environment
by Wenqiang Zhang, Xiaobing Chen, Xiangwei Zhou, Jianhua Chen, Jianguo Yuan, Taibiao Zhao and Kehui Xu
J. Mar. Sci. Eng. 2024, 12(7), 1091; https://doi.org/10.3390/jmse12071091 - 28 Jun 2024
Viewed by 371
Abstract
Deep learning methods paired with sidescan sonar (SSS) are commonly used in underwater search-and-rescue operations for drowning victims, wrecks, and airplanes. However, these techniques are primarily used to detect mine-like objects and are rarely applied to identifying features in dynamic dredge pit environments. [...] Read more.
Deep learning methods paired with sidescan sonar (SSS) are commonly used in underwater search-and-rescue operations for drowning victims, wrecks, and airplanes. However, these techniques are primarily used to detect mine-like objects and are rarely applied to identifying features in dynamic dredge pit environments. In this study, we present a Sandy Point dredge pit (SPDP) dataset, in which high-resolution SSS data were collected from the west flank of the Mississippi bird-foot delta on the Louisiana inner shelf. This dataset contains a total of 385 SSS images. We then introduce a new Effective Geomorphology Classification model (EGC). Through ablation studies, we analyze the utility of transfer learning on different model architectures and the impact of data augmentations on model performance. This EGC model makes geomorphic feature identification in dredge pit environments, which requires extensive experience and professional knowledge, a quick and efficient task. The combination of SSS images and the EGC model is a cost-effective and valuable toolkit for hazard monitoring in marine dredge pit environments. The SPDP SSS image dataset, especially the feature of pit walls without a rotational slump, is also valuable for other machine learning models. Full article
(This article belongs to the Section Coastal Engineering)
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13 pages, 1809 KiB  
Article
Short-Term Exposure to Ambient Air Pollution and Schizophrenia Hospitalization: A Case-Crossover Study in Jingmen, China
by Yuwei Zhou, Jixing Yang, Jingjing Zhang, Yixiang Wang, Jiajun Shen, Yalin Zhang, Yuxi Tan, Yunquan Zhang and Chengyang Hu
Atmosphere 2024, 15(7), 771; https://doi.org/10.3390/atmos15070771 - 27 Jun 2024
Viewed by 249
Abstract
The impact of short-term exposure to air pollutants on the morbidity of schizophrenia, particularly in low- and middle-income countries, remains inadequately explored. The objective of this research was to investigate the relationship between short-term exposure to ambient air pollutants and the risk of [...] Read more.
The impact of short-term exposure to air pollutants on the morbidity of schizophrenia, particularly in low- and middle-income countries, remains inadequately explored. The objective of this research was to investigate the relationship between short-term exposure to ambient air pollutants and the risk of schizophrenia hospitalization in Jingmen, China. We performed a time-stratified case-crossover study using daily records of hospital admissions due to schizophrenia in Jingmen Mental Health Center from 2015 to 2017. Environmental exposures to air pollutants and meteorological conditions on case and control days were estimated on the basis of measurements from ground monitoring stations. To investigate the relationship between short-term exposure to ambient air pollutants and the risk of hospitalization for schizophrenia, a conditional logistic regression model was employed. We performed subgroup analyses stratified according to sex, age groups, and season. In total, 4079 schizophrenia hospitalizations were recorded during the designated period. Increased risk of schizophrenia was merely associated with short-term exposure to SO2 and NO2. The estimated odds per interquartile range (IQR) increase in exposure was 1.112 (95% confidence interval (CI): 1.033, 1.196) for SO2 (IQR = 12 µg/m3) and 1.112 (95% CI: 1.033, 1.197) for NO2 (IQR = 18 µg/m3) on lag-0 day. Greater air pollution-schizophrenia associations were observed among middle-aged and older adults (over 45 years of age) and during the cold season. This study added case-crossover evidence indicating that short-term exposure to ambient air pollution, specifically SO2 and NO2, is linked to a higher risk of hospital admissions for schizophrenia. These findings contribute to a better understanding of the detrimental effects of air pollution on neuropsychiatric health conditions. Full article
(This article belongs to the Special Issue Outdoor Air Pollution and Human Health (3rd Edition))
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16 pages, 4575 KiB  
Article
Evaluation of the Immune Response of Patulin by Proteomics
by Feng Wang, Lukai Ma, Qin Wang, Bruce D. Hammock, Gengsheng Xiao and Ruijing Liu
Biosensors 2024, 14(7), 322; https://doi.org/10.3390/bios14070322 - 27 Jun 2024
Viewed by 526
Abstract
Patulin, an emerging mycotoxin with high toxicity, poses great risks to public health. Considering the poor antibody production in patulin immunization, this study focuses on the four-dimensional data-independent acquisition (4D-DIA) quantitative proteomics to reveal the immune response of patulin in rabbits. The rabbit [...] Read more.
Patulin, an emerging mycotoxin with high toxicity, poses great risks to public health. Considering the poor antibody production in patulin immunization, this study focuses on the four-dimensional data-independent acquisition (4D-DIA) quantitative proteomics to reveal the immune response of patulin in rabbits. The rabbit immunization was performed with the complete developed antigens of patulin, followed by the identification of the immune serum. A total of 554 differential proteins, including 292 up-regulated proteins and 262 down-regulated proteins, were screened; the differential proteins were annotated; and functional enrichment analysis was performed. The differential proteins were associated with the pathways of metabolism, gene information processing, environmental information processing, cellular processes, and organismal systems. The functional enrichment analysis indicated that the immunization procedures mostly resulted in the regulation of biochemical metabolic and signal transduction pathways, including the biosynthesis of amino acid (glycine, serine, and threonine), ascorbate, and aldarate metabolism; fatty acid degradation; and antigen processing and presentation. The 14 key proteins with high connectivity included G1U9T1, B6V9S9, G1SCN8, G1TMS5, G1U9U0, A0A0G2JH20, G1SR03, A0A5F9DAT4, G1SSA2, G1SZ14, G1T670, P30947, P29694, and A0A5F9C804, which were obtained by the analysis of protein–protein interaction networks. This study could provide potential directions for protein interaction and antibody production for food hazards in animal immunization. Full article
(This article belongs to the Special Issue Immunoassays and Biosensing)
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