Search Results (281)

Against a backdrop of rapid environmental degradation and increasing pressures on natural resources, a broad list of innovations has emerged to support the vision of the post-2020 Kunming-Montreal Global Biodiversity Framework and strengthen regional and country-level biodiversity strategies along the interface of protected areas and non-protected lands. The success of these strategies depends in large part on science-informed consideration and approaches to the underlying and indirect drivers of change for natural systems and ecosystem services. This paper aims to inform future strategies and action plans for conservation efforts and sustainable practices globally and regionally, with a specific focus on Latin America’s environmental challenges. Bibliometric analysis, covering two decades from 2003 to 2023, focused on global and Latin American research trends related to the indirect drivers of change for natural systems and ecosystem services at the interface of protected and non-protected lands. Through structured analysis, key opportunities for increased collaboration, impact, and research focus are identified, highlighting the need to expand research collaboration strategies and reach, enhance research dissemination through open and equitable innovations, and strengthen capacity to the complex and interrelated challenges underlying accelerated change in natural systems, which affects biodiversity and ecosystem services. Full article

In order to explore the formation mechanism of the emulsion gel induced by high pressure processing (HPP) and its encapsulation and protection of functional ingredients, a curcumin-loaded whey protein isolate (WPI)/κ-carrageenan (κ-CG) composite emulsion gel induced by HPP was prepared. The effect of pressure (400, 500 and 600 MPa), holding time (10, 20 and 30 min) and concentration of κ-CG (0.8%, 1.0% and 1.2%, w/v) on the swelling rate, gel strength, the stability of curcumin in the emulsion gel, water distribution and its mobility, as well as the contents of interface protein were characterized. The results showed that the addition of κ-CG significantly reduced the protein concentration required for the formation of emulsion gel induced by HPP and greatly reduced the swelling rate of the emulsion gel. The gel strength and storage stability of the composite emulsion gels increased with the increase in pressure (400–600 MPa) and holding time (10–30 min). When the pressure increased to 500 MPa, the stability of curcumin in the emulsion gel significantly improved. When the ratio of WPI to κ-CG was 12:1 (the κ-CG concentration was 1.0%), both the photochemical and thermal stability of curcumin were higher than those of the other two ratios. The HPP significantly increased the mobility of monolayer water in the system, while the mobility of multilayer water and immobilized water was significantly reduced. Increasing the holding time and the concentration of κ-CG both can result in an increase in the interfacial protein content in the oil/water system, and the HPP treatment had a significant effect on the composition of the interfacial protein of the emulsion gel. Full article

Molten chloride salts hold significant promise as both thermal transfer and storage media for next-generation concentrated solar power (CSP) systems. However, molten chlorides pose a considerable corrosion risk to structural materials, particularly Ni-based alloys. One approach to enhancing corrosion resistance is through the optimization of grain structure; however, it remains uncertain whether increasing or decreasing grain size enhances corrosion resistance. A cellular automata (CA) program was developed to evaluate the interplay between grain size and corrosion in Ni-based alloy. Our CA program tracks alloy composition, surface roughness, and thickness loss via a graphical user interface, displaying corrosion and diffusion status, and multiple user input cards for tuning the simulation. CA simulations of Inconel 625 indicate enhanced corrosion resistance with increased grain size, with passivating oxides offering limited protection. Additionally, the temporal evolution of alloy surface roughness demonstrates notable fluctuations, with abrupt increases attributed to corrosion along vertical grain boundaries and sudden decreases to grain detachment from the protective film. Full article

The Windows registry contains a plethora of information in a hierarchical database. It includes system-wide settings, user preferences, installed programs, and recently accessed files and maintains timestamps that can be used to construct a detailed timeline of user activities. However, these data are unencrypted and thus vulnerable to exploitation by malicious actors who gain access to this repository. To address this security and privacy concern, we propose a novel approach that efficiently encrypts and decrypts sensitive registry data in real time. Our developed proof-of-concept program intercepts interactions between the registry’s application programming interfaces (APIs) and other Windows applications using an advanced hooking technique. This enables the proposed system to be transparent to users without requiring any changes to the operating system or installed software. Our approach also implements the data protection API (DPAPI) developed by Microsoft to securely manage each user’s encryption key. Ultimately, our research provides an enhanced security and privacy framework for the Windows registry, effectively fortifying the registry against security and privacy threats while maintaining its accessibility to legitimate users and applications. Full article

In this study, the fundamentals of electroencephalography signals, their categorization into frequency sub-bands, the circuitry used for their acquisition, and the impact of noise interference on signal acquisition are examined. Additionally, design specifications for medical-grade and research-grade EEG circuits and a comprehensive analysis of various analog front-end architectures for electroencephalograph (EEG) circuit design are presented. Three distinct selected case studies are examined in terms of comparative evaluation with generic EEG circuit design templates. Moreover, a novel one-channel battery-supplied EEG analog front-end circuit designed to address the requirements of usage protocols containing strong compound muscle movements is introduced. Furthermore, a realistic input signal generator circuit is proposed that models the human body and the electromagnetic interference from its surroundings. Experimental simulations are conducted in 50 Hz and 60 Hz electrical grid environments to evaluate the performance of the novel design. The results demonstrate the efficacy of the proposed system, particularly in terms of bandwidth, portability, Common Mode Rejection Ratio, gain, suppression of muscle movement artifacts, electrostatic discharge and leakage current protection. Conclusively, the novel design is cost-effective and suitable for both commercial and research single-channel EEG applications. It can be easily incorporated in Brain–Computer Interfaces and neurofeedback training systems. Full article

We revealed that the encapsulation of enzyme-immobilized silica particles in hollow-type spherical bacterial cellulose (HSBC) gels enables the use of the inside of HSBC gels as a reaction field. The encapsulation of horseradish peroxidase (HRP)-immobilized silica particles (Si-HRPs, particle size: 40–50 μm) within HSBC gels was performed by using a BC gelatinous membrane produced at the interface between Komagataeibacter xylinus suspension attached onto an alginate gel containing Si-HRPs and silicone oil. After the biosynthesis of the BC gelatinous membrane, formed from cellulose nanofiber networks, the alginate gel was removed via immersion in a phosphate-buffered solution. Si-HRP encapsulated HSBC gels were reproducibly produced using our method with a yield of over 90%. The pore size of the network structure of the BC gelatinous membrane was less than 1 μm, which is significantly smaller than the encapsulated Si-HRPs. Consequently, the encapsulated Si-HRPs could neither pass through the BC gelatinous membrane nor leak from the interior cavity of the HSBC gel. The activity of the encapsulated HRPs was detected using the 3,3′,5,5′-tetramethylbenzidine (TMB)-H₂O₂ system, demonstrating that this method can encapsulate the enzyme without inactivation. Since HSBC gels are composed of a network structure of biocompatible cellulose nanofibers, immune cells cannot enter the hollow interior, thus, the enzyme-immobilized particles encapsulated inside the HSBC gel are protected from immune-cell attacks. The encapsulation technique demonstrated in this study is expected to facilitate the delivery of enzymes and catalysts that are not originally present in the in vivo environment. Full article

Energy security is a crucial issue for political, environmental, and economic reasons. This article presents a modern approach to securing critical infrastructure in energy transmission networks, which are managed by advanced IT systems. This paper focuses on the integration of cryptographic mechanisms with biometric data, providing an additional layer of protection against cyber threats. The discussed solutions enable the protection of management systems in energy transmission networks, enhancing their resilience to cyberattacks. The use of the command-line interface (CLI) in combination with biometrics allows for precise execution of security tasks such as network monitoring, firewall management, and automation of security tasks. This makes these systems more reliable and secure, which is essential for the stability of energy systems. Full article

Curcumin is a hydrophobic bioactive compound, and its incorporation into lipid-based carriers can enhance its bioaccessibility and maintain its stability over time. Pickering emulsions are long-term stability systems, effective for encapsulation, protection, and delivery of bioactive compounds. This study aimed to produce Pickering oil-in-water (O/W) emulsions stabilized by cassava starch nanoparticles (native or modified by heat–moisture treatment (HMT)) with high kinetic stability to encapsulate curcumin. The effect of curcumin incorporation on emulsion features was also assessed, as well as curcumin stability over time. Native starch nanoparticles (NSNPs) were not effective stabilizers in the concentration range of 0.8 to 4 wt%. Otherwise, modified starch nanoparticles (HSNPs) at 4 wt% produced a long-term stability Pickering emulsion, which was used to encapsulate curcumin (0.07 wt%). Confocal laser scanning microscopy (CLSM) showed that HSNPs were located at the droplet’s interface. The interfacial tension for HSNPs exhibited initial values from 40 to 33 mN/m, quickly reaching equilibrium. These findings suggest that HSNPs exhibit low surface activity and the stabilization mechanism of emulsion is based on steric hindrance. The stabilization by steric hindrance is supported by the low zeta potential value (−5.39 mV). Stable emulsions showed shear thinning behavior, and the power-law model demonstrated excellent fit to experimental data (R² ≥ 0.998). The addition of curcumin reduced the interfacial tension, droplet size, apparent viscosity, and consistency index, indicating that this bioactive compound can also act at the interface. After 60 days, curcumin degradation was fully avoided. Our findings indicated that HSNP-stabilized Pickering emulsions can protect encapsulated curcumin from degradation. Full article

Based on the goals of “high reliability, high frequency, rapid launch, and low cost” for space launch sites, an integrated dual-sided deflector system for convective cooling and thermal protection is presented. The interaction process between the gas jet and liquid water jet and its effect on the flow field environment are thoroughly studied using numerical calculation methods. Furthermore, considering the phase-change heat transfer issue in a compressible gas–liquid two-phase flow, and the varying distribution of different bubble shapes and sizes at the gas–liquid interface, a modified Lee model is derived. The research results show that compared to the classical Lee model, the modified Lee model can achieve a higher numerical accuracy in predicting the heat and mass transfer processes in gas–liquid two-phase flows. Through comparative analysis with the traditional dual-sided deflector and the conventional cooling system, the integrated dual-sided deflector system exhibits significant performance advantages in gas flow regulation and flow field environment improvement at the near-ground region of the space launch site. It not only achieves effective flow deflection, but also mitigates the degree of erosion caused by the gas jet on the deflector. This conclusion can provide theoretical references for the thermal protection design of commercial launch vehicle systems at space launch sites. Full article

Moebius syndrome is a collection of orofacial anomalies with highly variable features affecting many different systems but characterised by bilateral facial palsy and absent eye abduction. We largely regard Moebius syndrome as a diagnosis of exclusion. Lack of awareness and knowledge means that children often fall between services, leading to treatment delays and difficulty interfacing with social care and schools, with long-term impact on physical health and psychosocial development. We developed a multidisciplinary team comprising core clinicians (lead physician, geneticist, speech and language therapist, psychologist and specialist nurse) and an expanded group to encompass the other affected systems. The interactions between our specialties lead to the development of a treatment protocol, which we present. The protocol harnesses the aspects of care of children with a range of other rare diseases at a specialised paediatric centre and synthesises them into a holistic approach for MBS and related conditions. Management is sequenced on an “ABC-style” basis, with airway, feeding, vision and speech taking priority in the early years. We define management priorities as airway stabilisation with swallow assessment, ocular surface protection and maintenance of nutritional support. Management principles for issues such as speech, reflux, drooling and sleep issues are outlined. In later years, psychological support has a prominent role geared towards monitoring and interventions for low mood, self-esteem and bullying. Full article

This paper presents research on the mass dispersion and adsorption of organics present in tap water on powdered activated carbon (PAC) in a two-layer filter column. The adsorption rate depends on the difference between the concentration of organics and the equilibrium concentration. In homogeneous flocculators with simultaneous adsorption on PAC, the concentration difference is lower than in a filter column with PAC. Therefore, the utilization of the PAC’s adsorption capacity in filters is higher than in homogeneous flocculators. PAC is introduced into the upper anthracite layer of a filter bed, while the bottom layer is a sand layer, which protects the underdrain system from becoming clogged with PAC particles. The sorbent wis introduced into the bed in the final phase of filter backwashing. The authors present a model of adsorption on PAC in a filter column. Both experiments and calculations confirmed a better utilization of PAC’s adsorption capacity in the filter column compared to its utilization in a homogeneous flocculator. Three criterion equations were developed using dimensionless numbers, Re, Pe and Nu, as well as two similarity moduli related to a sorbent apparent density and an adsorption coefficient. Additionally, a relationship between the Peclet number (Pe) and the Reynolds number (Re) as well as the similarity modulus for the sorbent apparent density were determined for the mass dispersion process. The relationship between the diffusive Nuselt number (Nu) and the Re number as well as the similarity modulus for the sorbent apparent density were determined for the parameter describing an adsorbate permeation rate across a water–sorbent interface. The impact of the Re number and the similarity modulus for the sorbent apparent density on the Henry constant was also investigated. The criterion equations can be used to determine the adsorption model parameters; they may be helpful in designing a filtration system supplemented with PAC. In the capillary velocity range $V_x^{*}$ ∈ ⟨0.15·10⁻²; 0.72·10⁻²⟩ m/s and with a change in the apparent density of the sorbent ${\rho }_{p,sorb}$ from 3000 to 12,000 g PAC/m³ of the bed, as a result of the experimental tests carried out, it was established that the actual coefficient of longitudinal dispersion $D_x^{*}$ varied in the range of 0.16·10⁻⁴ to 2.03·10⁻⁴ m²/s, the product of the constant mass transfer rate and the specific outer surface of sorbent $k\cdot a_m$ varied in the range of 2.23·10⁻⁷ to 1.70·10⁻⁶ (m/s)·(m²/g PAC), while the Henry constant Γ* varied in the range of 7.24 to 44.20 1/m³ of sorbent and the Henry constant Γ varied in the range of 0.0012 to 0.0019 m³ of water/g PAC. Full article

With the emergence of autonomous functions in road vehicles, there has been increased use of Advanced Driver Assistance Systems comprising various sensors to perform automated tasks. Light Detection and Ranging (LiDAR) is one of the most important types of optical sensor, detecting the positions of obstacles by representing them as clusters of points in three-dimensional space. LiDAR performance degrades significantly when a vehicle is driving in the rain as raindrops adhere to the outer surface of the sensor assembly. Performance degradation behaviors include missing points and reduced reflectivity of the points. It was found that the extent of degradation is highly dependent on the interface material properties. This subsequently affects the shapes of the adherent droplets, causing different perturbations to the optical rays. A fundamental investigation is performed on the protective polycarbonate cover of a LiDAR assembly coated with four classes of material—hydrophilic, almost-hydrophobic, hydrophobic, and superhydrophobic. Water droplets are controllably dispensed onto the cover to quantify the signal alteration due to the different droplets of various sizes and shapes. To further understand the effects of droplet motion on LiDAR signals, sliding droplet conditions are simulated using numerical analysis. The results are validated with physical optical tests, using a 905 nm laser source and receiver to mimic the LiDAR detection mechanism. Comprehensive explanations of LiDAR performance degradation in rain are presented from both material and optical perspectives. These can aid component selection and the development of signal-enhancing strategies for the integration of LiDARs into vehicle designs to minimize the impact of rain. Full article

The traditional neuron-centric view of the central nervous system (CNS) is shifting toward recognizing the importance of communication between the neurons and the network of glial cells. This shift is leading to a more comprehensive understanding of how glial cells contribute to CNS function. Alongside this shift, recent discoveries have illuminated the significant role of the human microbiome, comprising trillions of microorganisms, mirroring the number of human cells in an individual. This paper delves into the multifaceted functions of neuroglia, or glial cells, which extend far beyond their traditional roles of supporting and protecting neurons. Neuroglia modulate synaptic activity, insulate axons, support neurogenesis and synaptic plasticity, respond to injury and inflammation, and engage in phagocytosis. Meanwhile, the microbiome, long overlooked, emerges as a crucial player in brain functionality akin to glial cells. This review aims to underscore the importance of the interaction between glial cells and resident microorganisms in shaping the development and function of the human brain, a concept that has been less studied. Through a comprehensive examination of existing literature, we discuss the mechanisms by which glial cells interface with the microbiome, offering insights into the contribution of this relationship to neural homeostasis and health. Furthermore, we discuss the implications of dysbiosis within this interaction, highlighting its potential contribution to neurological disorders and paving the way for novel therapeutic interventions targeting both glial cells and the microbiome. Full article

A strain isolation pad is a critical connection mechanism that enables deformation coordination between the rigid thermal insulation tile and the primary structure in the thermal protection system of a reusable hypersonic vehicle. An experimental investigation has been conducted to determine the static, loading–unloading, and high-cycle fatigue (HCF) responses of the SIP with 0.2 mm adhesive under through-thickness tension at room temperature. The contributions of the rigid thermal insulation tile and metallic substructure have not been considered so far. The results indicate that the tensile behavior of the SIP joint is highly nonlinear. The static and fatigue tensile failures both initiate from the corner close to the adhesive/SIP interface due to the stress concentration and the edge effect. The uniform breakage of the aramid fiber can be seen on the cross-section. A novel method is proposed to quantify the residual strain due to the short-time ratcheting effect of the SIP joint in the initial loading–unloading tensile response. As the number of fatigue cycles increases, the thickness of the SIP joint continues to increase until failure. An explicit expression associated with the growth of SIP joint thickness, fatigue cycle number, and peak cyclic stress is established. The turning point of the thickness growth rate with the fatigue cycle number is proposed as a new fatigue failure index for the SIP joint under tensile fatigue, and a fatigue life prediction model is developed. Full article

Corrosion processes at cut edges of galvanized steels proceed as highly localized electrochemical reactions between the exposed bulk steel matrix and the protective thin metallic coating of a more electrochemically active material. Scanning microelectrochemical techniques can thus provide the spatially resolved information needed to assess the corrosion initiation and propagation phenomena, yet most methods scan cut edge sections as embedded in insulating resin to achieve a flat surface for scanning purposes. In this work, the galvanized coatings on both sides of the material were concomitantly exposed to simulated acid rain while characterizing the cut edge response using SECM and SVET techniques, thereby maintaining the coupled effects through the exposure of the whole system as rather realistic operation conditions. The cut edges were shown to strongly promote oxygen consumption and subsequent alkalization to pH 10–11 over the iron, while diffusion phenomena eventually yielded the complete depletion of oxygen and pH neutralization of the nearby electrolyte. In addition, the cathodic activation of the exposed iron was intensified with a thinner coating despite the lower presence of sacrificial anode, and preferential sites of the attack in the corners revealed highly localized acidification below pH 4, which sustained hydrogen evolution at spots of the steel-coating interface. Full article