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Search Results (2,432)

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16 pages, 5811 KiB  
Article
Enhancing Spraying Performance with Active Stability Control in Multi-Link Mechanisms
by Naiyu Shi, He Li, Yongkang Yang, Hongliang Hua, Junhong Ye, Zheng Chen and Ting Xu
Machines 2025, 13(2), 104; https://doi.org/10.3390/machines13020104 - 28 Jan 2025
Viewed by 105
Abstract
This study proposes an active stability control method for the multi-link mechanism of spraying equipment to enhance its spraying performance. Traditional spraying operations typically focus on protecting only the tops of crops, whereas the multi-link mechanism can adjust the angle and position of [...] Read more.
This study proposes an active stability control method for the multi-link mechanism of spraying equipment to enhance its spraying performance. Traditional spraying operations typically focus on protecting only the tops of crops, whereas the multi-link mechanism can adjust the angle and position of the nozzles in coordination, achieving comprehensive protection for the crops. However, the characteristic of uneven output speed in the multi-link mechanism results in variations in the spraying amount at different positions. To address this issue, this study developed a method for actively adjusting the stability of the output end speed. First, a differential equation was established to relate the input speed to the output speed using vector methods, implicit function transformation to explicit functions, and regression analysis. The feasibility of this method was verified through simulations using MATLAB Simulink R2018a and Adams 2018. Prototype test results indicate that this speed adjustment method improved the stability of the output angular velocity, reducing the coverage rate variation between the upward, sideways, and downward of the leaves by 12.53% during the spraying process. Therefore, the method proposed in this study can enhance the uniformity of spraying, further improving the utilization of pesticides, which is beneficial for the green ecological sustainable development in the agricultural field. Additionally, this control method is also applicable to other types of link mechanisms, providing a reference for improving the output stability of link mechanisms. Full article
(This article belongs to the Section Machine Design and Theory)
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16 pages, 4676 KiB  
Article
A Thermodynamic and Experimental Analysis of Inclusions Modification in AH36 Liquid Steel by Calcium and Magnesium Treatment
by Lei Kang, Xiangwei Liao, Peng Zhang, Hui Kong and Ting Wu
Metals 2025, 15(2), 126; https://doi.org/10.3390/met15020126 - 27 Jan 2025
Viewed by 278
Abstract
The influence of calcium and magnesium treatment under different molten steel conditions, as well as that of the alloy proportion and addition sequence of calcium and magnesium in composite treatment, on the evolution of inclusions in AH36 liquid steel was analyzed systematically based [...] Read more.
The influence of calcium and magnesium treatment under different molten steel conditions, as well as that of the alloy proportion and addition sequence of calcium and magnesium in composite treatment, on the evolution of inclusions in AH36 liquid steel was analyzed systematically based on thermodynamic calculations. The results show that the inclusions in molten steel are mainly Al2O3, which gradually transform into a liquid phase after calcium treatment with a wide range of calcium contents, indicating that calcium treatment has a significant effect on inclusion modification. Magnesium treatment mainly converts Al2O3 into MgO·Al2O3 inclusions in molten steel; however, it is not suitable to modify inclusions with magnesium treatment alone since it does not produce a significant liquid phase. The effect of calcium and magnesium composite treatment varies with the alloy content composition and the order of alloy addition. The liquid phase range of inclusions follows the order of 80%Ca + 20%Mg composite treatment > calcium treatment > 50%Ca + 50%Mg composite treatment > 20%Ca + 80%Mg composite treatment. Combining the thermodynamic and experimental analysis results, it can be concluded that the composite treatment of magnesium followed by calcium is the best. Specifically, a small amount of magnesium should be added first as the nucleating particle to promote the fine dispersion of the inclusions, thus reducing their impact on steel performance. Then, calcium should be added to modify the surface of the inclusions into a liquid phase, which can effectively reduce nozzle clogging. Full article
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18 pages, 10143 KiB  
Article
Features of Supersonic Flow Around a Blunt Body in the Area of Junction with a Flat Surface
by T. A. Lapushkina, E. V. Kolesnik, N. A. Monahov, P. A. Popov and K. I. Belov
Fluids 2025, 10(2), 28; https://doi.org/10.3390/fluids10020028 - 26 Jan 2025
Viewed by 173
Abstract
This work studies the influence of a growing boundary layer on the process of supersonic flow around an aerodynamic body. The task is to select and implement in an experiment the parameters of a supersonic flow and to study the flow pattern near [...] Read more.
This work studies the influence of a growing boundary layer on the process of supersonic flow around an aerodynamic body. The task is to select and implement in an experiment the parameters of a supersonic flow and to study the flow pattern near the surface of an aerodynamic body at different viscosity values for the incoming flow. Visualization of the shock wave configuration in front of the body and studying the change in the pressure field in the flow region under these conditions is the main goal of this work. The experiment was carried out on an experimental stand created on the basis of a shock tube. The aerodynamic body under study (a semi-cylinder pointed along a circle or an ellipse) was placed in a supersonic nozzle. The model was clamped by lateral transparent walls, which were simultaneously a source of boundary layer growth and the viewing windows for visualizing the flow. For selected modes with Reynolds numbers from 8200 to 45,000, schlieren flow patterns and pressure distribution fields near the surface of the streamlined models and the plate of the growing boundary layer were obtained. The data show a complex, unsteady flow pattern realized near the model which was caused by the viscous-inviscid interaction of the boundary layer with the bow shock wave near the wall. Full article
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34 pages, 2511 KiB  
Article
The Effect of Layer Thickness and Nozzle Diameter in Fused Deposition Modelling Printing on the Flexural Strength of Zirconia Ceramic Samples Produced by a Multistage Manufacturing Process
by Anton Smirnov, Oleg Yanushevich, Natella Krikheli, Yulia Zhukovskaya, Mihail Soloninkin, Petr Naumenko, Nestor Washington Solis Pinargote, Pavel Peretyagin, Sergey Grigoriev and Nikita Nikitin
Ceramics 2025, 8(1), 10; https://doi.org/10.3390/ceramics8010010 - 24 Jan 2025
Viewed by 260
Abstract
The process of creating ceramic items using fused deposition modelling (FDM) enables the creation of intricate shapes for a variety of purposes, including tooling and prototyping. However, due to the numerous variables involved in the process, it is challenging to discern the impact [...] Read more.
The process of creating ceramic items using fused deposition modelling (FDM) enables the creation of intricate shapes for a variety of purposes, including tooling and prototyping. However, due to the numerous variables involved in the process, it is challenging to discern the impact of each parameter on the final characteristics of FDM components, which impedes the advancement of this technology. This paper deals with the application of statistical analysis in the study of the dependence of the flexural strength of sintered zirconia disks on the printing parameters (nozzle diameter, layer thickness, and infill pattern) of the fused deposition method printing of a ceramic–polymer filament containing 80 wt.% zirconia and 20 wt.% polylactide. X-ray-computed tomography and diffraction systems, scanning electron microscopy combined with energy-dispersive spectroscopy, were used for a microstructural analysis of the sintered samples. It was found that the nozzle diameter and infill pattern have no significant influence on the flexural strength values. It was assumed that this is due to the heterogeneous distribution of the ceramic phase in the manufactured filament during extrusion. On the other hand, correlation analysis and analysis of correlation diagrams have shown that the thickness of the filling layer has the greatest effect on flexural strength. The maximum (684 МPa) strength value was found in a sample printed with a layer thickness of 0.2 mm. The minimum layer thickness ensures a more uniform distribution of ceramic particles and minimizes defects in samples that occur during FDM printing. The results obtained make it possible to optimize the considered process of manufacturing ceramic products from ZrO2 printed using FDM technology from extruded composite filaments. Full article
20 pages, 41337 KiB  
Article
Noise Reduction Using Synthetic Microjet Excitation in Supersonic Rectangular Jets
by Michael Marques, Surabhi Singh, Anastasios Lyrintzis and Vladimir Golubev
Appl. Sci. 2025, 15(3), 1180; https://doi.org/10.3390/app15031180 - 24 Jan 2025
Viewed by 324
Abstract
This work explores a potential methodology for rectangular jet noise reduction that employs nozzle unsteady microjet excitation. Using high-fidelity computational studies and spectral analyses, major jet noise sources impacted by the applied actuation are identified. A heated supersonic rectangular jet is considered with [...] Read more.
This work explores a potential methodology for rectangular jet noise reduction that employs nozzle unsteady microjet excitation. Using high-fidelity computational studies and spectral analyses, major jet noise sources impacted by the applied actuation are identified. A heated supersonic rectangular jet is considered with a nozzle aspect ratio of 2:1 at a Mach number of 1.5. The current study essentially validates the hypothesis of a previous reduced-order analysis that predicted jet noise reduction through jet excitation at the harmonic or subharmonic of the dominant frequency associated with jets’ large-scale structures. Such noise reduction was attributed to the excitation-induced nonlinear energy exchange between the coherent modes. In the current study, the synthetic microjet actuation of the jet plume shear layer using 1% of the jet mass flow rate is implemented at the excitation ports located at the nozzle lip and directed along the jet axis. A resulting jet noise reduction of up to 4 dB at the peak radiation angle is predicted. An analysis of the near-field Spectral Proper Orthogonal Decomposition (SPOD) results provides further insights into the impact of jet actuation on the modification of jet flow structures, thus addressing the effectiveness of the proposed noise control methodology. Full article
(This article belongs to the Section Acoustics and Vibrations)
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21 pages, 3124 KiB  
Review
Recent Advances in Cooling Technology for the Leading Edge of Gas Turbine Blades
by Shixing Zhu, Yan Li, Junyang Yan and Chao Zhang
Energies 2025, 18(3), 540; https://doi.org/10.3390/en18030540 - 24 Jan 2025
Viewed by 313
Abstract
As the inlet temperature of the gas turbine exceeds the high temperature limit of the blade materials, efficient leading edge cooling technologies are crucial for the further development of gas turbines. Therefore, this paper reviews the research progress on external cooling technology, internal [...] Read more.
As the inlet temperature of the gas turbine exceeds the high temperature limit of the blade materials, efficient leading edge cooling technologies are crucial for the further development of gas turbines. Therefore, this paper reviews the research progress on external cooling technology, internal cooling technology, and composite cooling technology for gas turbine rotating blade leading edge cooling. It focuses on the impact of the geometric shape, arrangement, and flow parameters of film cooling holes on external cooling performance, the influence of jet hole design, configuration, crossflow, ribs on internal cooling efficiency, and the characteristics and influencing factors of composite cooling technologies are also discussed. Among the most promising composite cooling techniques, the impingement jet film composite cooling technology and swirl film composite cooling technology stand out. For impingement jet film composite cooling technology, this paper explores the effects of blowing ratio, nozzle parameters, jet hole characteristics, and flow field parameters on the overall cooling performance of the rotating blade leading edge. Impingement jet film composite cooling technology has been shown to significantly improve the cooling performance of the leading edge compared to traditional single cooling techniques. For applications requiring large area cooling or maintaining film integrity, swirl film composite cooling technology not only enhances heat transfer efficiency but also improves the uniformity of heat transfer. The design of swirl nozzles, coolant flow rate, Reynolds number, and jet temperature all have significant effects on the heat transfer efficiency of swirl film composite cooling. To further advance the development of gas turbine rotating blade leading edge cooling technologies, it is recommended to focus on the study of film composite cooling techniques, particularly investigating the effects of various parameters of impingement, swirl on composite cooling performance. Full article
(This article belongs to the Section J: Thermal Management)
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13 pages, 12021 KiB  
Article
Production of Monodisperse Oil-in-Water Droplets and Polymeric Microspheres Below 20 μm Using a PDMS-Based Step Emulsification Device
by Naotomo Tottori, Seungman Choi and Takasi Nisisako
Micromachines 2025, 16(2), 132; https://doi.org/10.3390/mi16020132 - 24 Jan 2025
Viewed by 317
Abstract
Step emulsification (SE) is renowned for its robustness in generating monodisperse emulsion droplets at arrayed nozzles. However, few studies have explored poly(dimethylsiloxane) (PDMS)-based SE devices for producing monodisperse oil-in-water (O/W) droplets and polymeric microspheres with diameters below 20 µm—materials with broad applicability. In [...] Read more.
Step emulsification (SE) is renowned for its robustness in generating monodisperse emulsion droplets at arrayed nozzles. However, few studies have explored poly(dimethylsiloxane) (PDMS)-based SE devices for producing monodisperse oil-in-water (O/W) droplets and polymeric microspheres with diameters below 20 µm—materials with broad applicability. In this study, we present a PDMS-based microfluidic SE device designed to achieve this goal. Two devices with 264 nozzles each were fabricated, featuring straight and triangular nozzle configurations, both with a height of 4 µm and a minimum width of 10 µm. The devices were rendered hydrophilic via oxygen plasma treatment. A photocurable acrylate monomer served as the dispersed phase, while an aqueous polyvinyl alcohol solution acted as the continuous phase. The straight nozzles produced polydisperse droplets with diameters exceeding 30 µm and coefficient-of-variation (CV) values above 10%. In contrast, the triangular nozzles, with an opening width of 38 µm, consistently generated monodisperse droplets with diameters below 20 µm, CVs below 4%, and a maximum throughput of 0.5 mL h−1. Off-chip photopolymerization of these droplets yielded monodisperse acrylic microspheres. The low-cost, disposable, and scalable PDMS-based SE device offers significant potential for applications spanning from laboratory-scale research to industrial-scale particle manufacturing. Full article
(This article belongs to the Special Issue Recent Advances in Droplet Microfluidics)
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21 pages, 11129 KiB  
Article
Investigation on Flow Features and Combustion Characteristics in a Boron-Based Solid-Ducted Rocket Engine
by Xiang Tang, Xiaotao Tian, Liang Zhu, Suli Wu, Meng Huang and Weixuan Li
Energies 2025, 18(3), 524; https://doi.org/10.3390/en18030524 - 23 Jan 2025
Viewed by 351
Abstract
Numerical and experimental approaches are conducted to investigate the flow features and secondary combustion performance induced by different air–fuel ratios in a boron-based solid-ducted rocket engine. The results indicated that the afterburning chamber flow features become more complicated owing to the multiple nozzles [...] Read more.
Numerical and experimental approaches are conducted to investigate the flow features and secondary combustion performance induced by different air–fuel ratios in a boron-based solid-ducted rocket engine. The results indicated that the afterburning chamber flow features become more complicated owing to the multiple nozzles of the gas injector, and a number of recirculation zones are generated. Because of this, the mixing of the fuel gas and incoming air is enhanced. When the air–fuel ratio decreases, the heat release in the afterburning chamber increases continuously, which causes the pre-combustion shock train to continue to propagate upstream in the subsonic diffuser of the inlet isolator, along with the boundary layer separation zone also moving forward, and the stability margin of the direct-connect inlet decreasing gradually. Furthermore, the direct-connect inlet works at a critical state with an air–fuel ratio of 11.5. As the mass flow rate of the fuel-rich gas rises gradually, the engine thrust gradually increases, and the number of vortexes in the afterburning chamber and the corresponding region affected by the vortexes generally decrease. Meanwhile, the mixing and combustion of the fuel-rich gas and incoming flow were not substantially changed. Additionally, the combustion efficiency and specific impulse are proportional to the air fuel ratio. Full article
(This article belongs to the Section I2: Energy and Combustion Science)
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23 pages, 4816 KiB  
Article
Eco-Friendly Alternatives to Toluene-Based 2D Inks for Inkjet and Electrohydrodynamic Jet Printing Processes: A Rheological Study
by Pedro C. Rijo, Ilaria Tocci and Francisco J. Galindo-Rosales
Micromachines 2025, 16(2), 130; https://doi.org/10.3390/mi16020130 - 23 Jan 2025
Viewed by 377
Abstract
Green sustainable solvents have emerged as promising alternatives to petroleum-derived options, such as toluene. This study demonstrates the use of cyrene as an effective exfoliation medium for graphene nanoplatelets (GNPs) and hexagonal boron nitride (hBN) and molybdenum disulfide (MoS2) particles. The [...] Read more.
Green sustainable solvents have emerged as promising alternatives to petroleum-derived options, such as toluene. This study demonstrates the use of cyrene as an effective exfoliation medium for graphene nanoplatelets (GNPs) and hexagonal boron nitride (hBN) and molybdenum disulfide (MoS2) particles. The incorporation of polyvinylpyrrolidone (PVP) attenuates the shear-thinning behavior of GNP and hBN suspensions, maintaining a constant shear viscosity over a wide range of shear rates regardless of PVP molecular weight. Despite the presence of polymer, elasticity is hindered by inertia effects, making it impossible to accurately measure the extensional relaxation time in the capillary breakup extensional rheometer (CaBER). Assuming the weak elasticity of the formulations has a negligible impact on the breakup mechanism, we estimated droplet sizes for drop-on-demand (DoD) inkjet printing and electrohydrodynamic (EHD) jet printing based on fluid properties, i.e., viscosity, surface tension and density, and nozzle inner diameter (Dnozzle). Results indicate that the droplet size ratio (Ddrop/Dnozzle) in DoD printing can be up to two orders of magnitude higher than the one predicted for EHD jet printing at the same flow rate. This work highlights the potential of cyrene-based 2D inks as eco-friendly alternatives for advanced printing technologies. Full article
(This article belongs to the Special Issue Two-Dimensional Materials for Emerging Applications)
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22 pages, 7705 KiB  
Article
Investigations of Internal Flow Characteristics of Multi-Hole Nozzle Using X-Ray Imaging Technique
by Ya Gao, Pei Li and Weidi Huang
Processes 2025, 13(2), 309; https://doi.org/10.3390/pr13020309 - 23 Jan 2025
Viewed by 374
Abstract
This study introduces a novel application of synchrotron X-ray phase contrast imaging to investigate the internal flow dynamics and liquid jet characteristics in a direct injection gasoline nozzle. Using optimized imaging parameters, including a 19 mm insertion gap and a 0.15 ns electron [...] Read more.
This study introduces a novel application of synchrotron X-ray phase contrast imaging to investigate the internal flow dynamics and liquid jet characteristics in a direct injection gasoline nozzle. Using optimized imaging parameters, including a 19 mm insertion gap and a 0.15 ns electron pulse (16 mA), we achieved high-quality visualization of needle motion and in-nozzle flip flow. The results show that cavitation appears rapidly with increasing needle valve lift, transitioning from unstable behavior below 40 µm to stable flip flow at higher lifts. The flip flow characteristics vary between nozzle holes due to differences in inlet angles. Internal flow velocity analysis reveals significant radial and axial gradients, with initial velocity overshoot during injection start followed by stable flow. The presence of flip flow accelerates jet breakup on the flip-contact side, leading to droplet–wall interactions in the counterbore. Different nozzle geometries, particularly hole inlet angle and length-to-diameter ratio, significantly influence jet width and velocity distributions. This comprehensive approach advances our understanding of practical nozzle internal flow dynamics and provides valuable insights for optimizing fuel injection system performance in engines. Full article
(This article belongs to the Section Energy Systems)
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27 pages, 7310 KiB  
Article
Optimization of 3D Printing Nozzle Parameters and the Optimal Combination of 3D Printer Process Parameters for Engineering Plastics with High Melting Points and Large Thermal Expansion Coefficients
by Jun Wang, Hang Hu, Ziyi Liu, Yuanyuan Shi and Yizhe Huang
Materials 2025, 18(3), 500; https://doi.org/10.3390/ma18030500 - 22 Jan 2025
Viewed by 356
Abstract
Three-dimensional printing is a transformative technology in the manufacturing industry which provides customization and cost-effectiveness for all walks of life due to its fast molding speed, high material utilization, and direct molding of arbitrary complex structural parts. This study aims to improve the [...] Read more.
Three-dimensional printing is a transformative technology in the manufacturing industry which provides customization and cost-effectiveness for all walks of life due to its fast molding speed, high material utilization, and direct molding of arbitrary complex structural parts. This study aims to improve the molding accuracy of 3D printed polyether ether ketone (PEEK) samples by systematically studying key process parameters, including printing speed, layer thickness, nozzle temperature, and filling rate. The 3D printing nozzle has an important impact on the extrusion rate of the melt, and the fluid simulation of the nozzle was carried out to explore the variation characteristics of the melt flow rate in the nozzle and optimize the nozzle structure parameters. In order to effectively optimize the process, considering its inherent efficiency, robustness, and cost-effectiveness, the L9 orthogonal array experimental design scheme was used to analyze the effects of printing speed, layer thickness, nozzle temperature, and filling rate on the molding accuracy of the test sample, and the optimal combination of process parameters was optimized through the comprehensive weighted scoring method so as to improve the molding accuracy of the 3D printed PEEK sample; finally, the molding accuracy of the components printed using the Sermoon-M1 3D printer with the optimized nozzle structure was printed. The results show that the nozzle structure is optimal when the convergence angle is 120° and the aspect ratio is 2, and the outlet cross-section velocity is increased by 2.5% and 2.7%, respectively. The order of influence strength on the dimensional accuracy of the test sample is layer thickness > filling rate > nozzle temperature > printing speed. The optimal combination of parameters is: a printing speed of 15 mm/s, a layer thickness of 0.1 mm, a nozzle temperature of 420 °C, and a filling rate of 50%. The insights derived from this study pave the way for predicting and implementing the selection of optimal process parameters in the production of 3D printed products, with important implications for the optimal molding accuracy of printed components. Full article
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17 pages, 2389 KiB  
Article
Effects of Flight Heights and Nozzle Types on Spray Characteristics of Unmanned Aerial Vehicle (UAV) Sprayer in Common Field Crops
by Saurav Ranabhat and Randy Price
AgriEngineering 2025, 7(2), 22; https://doi.org/10.3390/agriengineering7020022 - 21 Jan 2025
Viewed by 606
Abstract
Effective spraying is an important component of precision agriculture, directly influencing the efficiency of the spray materials. Despite their potential, optimal settings for sprayer drones remain underexplored due to limited research data. This study evaluates the effects of various flight heights and nozzle [...] Read more.
Effective spraying is an important component of precision agriculture, directly influencing the efficiency of the spray materials. Despite their potential, optimal settings for sprayer drones remain underexplored due to limited research data. This study evaluates the effects of various flight heights and nozzle types on spray characteristics in cotton, soybean, and sugarcane crops using an unmanned aerial vehicle (UAV) sprayer. Three different flight heights and two or three nozzle types were evaluated for their impacts on spray deposition, coverage percentage, and droplet size distribution at three different canopy levels of these crops. The results indicated that lower flight heights significantly increased spray deposition and coverage in the upper canopy levels of cotton and sugarcane. Centrifugal nozzles consistently produced greater coverage and spray deposition in sugarcane. Some significant interactions among these factors were also explored. The findings highlight the potential for UAV sprayers to optimize spraying in crops with various morphologies by adjusting flight height and nozzle type. Full article
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24 pages, 17252 KiB  
Article
3D-Printing of Artificial Aortic Heart Valve Using UV-Cured Silicone: Design and Performance Analysis
by Atila Ertas, Erik Farley-Talamantes, Olkan Cuvalci and Ozhan Gecgel
Bioengineering 2025, 12(1), 94; https://doi.org/10.3390/bioengineering12010094 - 20 Jan 2025
Viewed by 521
Abstract
The advancement of medical 3D printing technology includes several enhancements, such as decreasing the length of surgical procedures and minimizing anesthesia exposure, improving preoperative planning, creating personalized replicas of tissues and bones specific to individual patients, bioprinting, and providing alternatives to human organ [...] Read more.
The advancement of medical 3D printing technology includes several enhancements, such as decreasing the length of surgical procedures and minimizing anesthesia exposure, improving preoperative planning, creating personalized replicas of tissues and bones specific to individual patients, bioprinting, and providing alternatives to human organ transplants. The range of materials accessible for 3D printing within the healthcare industry is significantly narrower when compared with conventional manufacturing techniques. Liquid silicone rubber (LSR) is characterized by its remarkable stability, outstanding biocompatibility, and significant flexibility, thus presenting substantial opportunities for manufacturers of medical devices who are engaged in 3D printing. The main objective of this study is to develop, refine, and assess a 3D printer that can employ UV-cured silicone for the fabrication of aortic heart valves. Additionally, the research aims to produce a 3D-printed silicone aortic heart valve and evaluate the feasibility of the final product. A two-level ANOVA experimental design was utilized to investigate the impacts of print speed, nozzle temperature, and layer height on the print quality of the aortic heart valve. The findings demonstrated that the 3D-printed heart valve’s UV-cured silicone functioned efficiently, achieving the target flow rates of 5 L/min and 7 L/min. Two distinct leaflet thicknesses (LT) of the heart valve, namely 0.8 mm and 1.6 mm, were also analyzed to simulate calcium deposition on the leaflets. Full article
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19 pages, 7637 KiB  
Article
Design of Ejectors for High-Temperature Heat Pumps Using Numerical Simulations
by Julian Unterluggauer, Adam Buruzs, Manuel Schieder, Verena Sulzgruber, Michael Lauermann and Christoph Reichl
Processes 2025, 13(1), 285; https://doi.org/10.3390/pr13010285 - 20 Jan 2025
Viewed by 480
Abstract
Decarbonization of industrial processes by using high-temperature heat pumps is one of the most important pillars towards sustainable energy goals. Most heat pumps are based on the standard Carnot cycle which includes an expansion valve leading to irreversible dissipation and energetic losses. Especially [...] Read more.
Decarbonization of industrial processes by using high-temperature heat pumps is one of the most important pillars towards sustainable energy goals. Most heat pumps are based on the standard Carnot cycle which includes an expansion valve leading to irreversible dissipation and energetic losses. Especially for high-temperature applications, these losses increase significantly, and a replacement of the conventional throttle valve with an ejector, which is an alternative expansion device, for partial recovery of some of the pressure lost during the expansion, is investigated in this paper. However, designing such a device is complicated as the flow inside is subject to multiphase and supersonic conditions. Therefore, this paper aims to streamline an approach for designing ejectors for high-temperature heat pumps using numerical simulations. To showcase the application of the design procedure, an ejector, which is used to upgrade a standard cycle high-temperature heat pump with the synthetic refrigerant R1233zdE, is developed. To design the ejector heat pump, an interaction between a fast 1D design tool, a 1D heat pump cycle simulation, and a 2D CFD simulation is proposed. An ejector is designed for a sink temperature of 130 °C, which can potentially increase the COP of the heat pump by around 20%. Preliminary measurements at off-design conditions at 100 °C sink temperature are used to validate the design procedure. The pressure distribution inside the ejector is well captured, with relative errors around 4%. However, the motive nozzle mass flow was underpredicted by around 30%. To summarize, the presented approach can be used for designing ejectors of high-temperature heat pumps, although the numerical modeling has to be further developed by validation with experiments to improve the prediction of the motive mass flow. Full article
(This article belongs to the Special Issue Heat and Mass Transfer Phenomena in Energy Systems)
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12 pages, 1987 KiB  
Article
Prilling as an Effective Tool for Manufacturing Submicrometric and Nanometric PLGA Particles for Controlled Drug Delivery to Wounds: Stability and Curcumin Release
by Chiara De Soricellis, Chiara Amante, Paola Russo, Rita Patrizia Aquino and Pasquale Del Gaudio
Pharmaceutics 2025, 17(1), 129; https://doi.org/10.3390/pharmaceutics17010129 - 17 Jan 2025
Viewed by 503
Abstract
Background/Objectives: This study investigates for the first time the use of the prilling technique in combination with solvent evaporation to produce nano- and submicrometric PLGA particles to deliver properly an active pharmaceutical ingredient. Curcumin (CCM), a hydrophobic compound classified under BCS (Biopharmaceutics Classification [...] Read more.
Background/Objectives: This study investigates for the first time the use of the prilling technique in combination with solvent evaporation to produce nano- and submicrometric PLGA particles to deliver properly an active pharmaceutical ingredient. Curcumin (CCM), a hydrophobic compound classified under BCS (Biopharmaceutics Classification System) class IV, was selected as the model drug. Methods: Key process parameters, including polymer concentration, solvent type, nozzle size, and surfactant levels, were optimized to obtain stable particles with a narrow size distribution determined by DLS analysis. Results: Particles mean diameter (d50) 316 and 452 nm, depending on drug-loaded cargo as Curcumin-loaded PLGA nanoparticles demonstrated high encapsulation efficiency, assessed via HPLC analysis, stability, and controlled release profiles. In vitro studies revealed a faster release for lower drug loadings (90% release in 6 h) compared to sustained release over 7 days for higher-loaded nanoparticles, attributed to polymer degradation and drug-polymer interactions on the surface of the particles, as confirmed by FTIR analyses. Conclusions: These findings underline the potential of this scalable technique for biomedical applications, offering a versatile platform for designing drug delivery systems with tailored release characteristics. Full article
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