Search Results (1,395)

Over the course of industrialization in the 20th century, vast emissions of air pollutants have occurred. The exhaust gasses contain sulfur and nitrogen oxides, which are converted to sulfuric acid and nitric acid in the atmosphere. This causes acid rain to enter aquatic and terrestrial ecosystems, the most serious consequence of which is large-scale forest dieback across Europe and North America. However, through various political measures, the exhaust gasses have been reduced and, thus, acid rain and forest dieback were stopped. Nevertheless, the lingering effects of this pollution are still present today and are reflected in hydrochemistry. More recently, fluctuating precipitation regimes are causing additional stress to ecosystems in Central Europe. Climatic extremes are becoming more pronounced with climate change. Substantial differences between drought years and years with regular precipitation are directly altering the discharge of springs. Now, two overlapping and interacting syndromes of environmental pressures can be studied in these small catchments at a landscape scale: (1) acidification and (2) climate change. In this long-term study, the waters of 102 forest springs, located in two neighboring forest landscapes in north-eastern Bavaria, Germany (Frankenwald and Fichtelgebirge), were investigated over 24 years (1996 to 2020). By linking changes in pH values with changes in precipitation and spring discharge, we found that pH increases with decreasing discharge and decreasing precipitation. This effect was strongest in the Frankenwald compared to the Fichtelgebirge. We hypothesize that this temporal pattern reflects the longer residence time and, in consequence, the increased buffering of acidic interflow in small catchments during periods of drought. However, this should not be misinterpreted as rapid recovery from acidification because this effect fades in times of enhanced precipitation. We recommend that fluctuations in weather regimes be considered when investigating biogeochemical patterns throughout forest landscapes. Full article

In recent years, the need to protect and conserve biodiversity has become more critical than ever before, as a prerequisite for both sustainable development and the very survival of the human species. This has made it a priority for the scientific community to develop technological solutions that provide data and information for monitoring, directly or indirectly, biodiversity and the drivers of change. A new era of satellite earth observation upgrades the potential of Remote Sensing (RS) to support, at relatively low cost, but with high accuracy the extraction of information over large areas, at regular intervals, and over extended periods of time. Also, the recent development of the Earth Observation Data Cubes (EODC) framework facilitates EO data management and information extraction, enabling the mapping and monitoring of temporal and spatial patterns on the Earth’s surface. This submission presents the ELBIOS EODC, specifically developed to support the biodiversity management and conservation over Greece. Based on the Open Data Cube (ODC) framework, it exploits multi-spectral optical Copernicus Sentinel-2 data and provides a series of Satellite Earth Observation (SEO) biodiversity products and spectral indices nationwide. Full article

Background: Transgender men use exogenous androgen for male pattern virilization. Hysterectomy and bilateral salpingo-oophorectomy (HBSO) is performed to stop the endogenous estrogen secretion. Cardiovascular disease (CVD) risk has been shown to increase with long-term use of androgens and the removal of estrogen. We aimed to investigate the CVD risk in these individuals by measuring internal and common carotid artery intima–media thicknesses (CIMT). Methods: In this cohort study, data were collected from transgender men who had undergone HBSO and used androgens for at least two years (median treatment duration was 5 years in our research). Cisgender women in the same age range were selected as the control group. Demographics, vital signs, and hematological values of transgender patients and cisgender women subjects in the control group were noted. CVD markers were compared with sonographically measured CIMT values. Results: The mean age and body mass index (BMI) of the study group were 32.6 and 25.3, respectively. Weight, systolic–diastolic blood pressure, hemoglobin, hematocrit, low-density lipoprotein (LDL), serum triglyceride (TG), HbA1c levels, internal CIMT, and common CIMT values of the study group were higher, while the high-density lipoprotein (HDL) level was significantly lower compared the control group (p1 = 0.025, p2 = 0.010, p3 = 0.002, p4 = 0.001, p5 = 0.001, p6 = 0.012, p7 = 0.008, p8 = 0.007, p9 = 0.013, and p10 = 0.001). There was also an increase in the body weight, BMI, LDL, and TG levels of the study group after the testosterone treatment (p1 = 0.025, p2 = 0.019, p3 = 0.001, p4 = 0.001, and p5 = 0.001). Conclusions: We demonstrated that the use of testosterone therapy in transgender men is associated with higher CIMT values. While further investigation is needed to assess morbidity and mortality rates, we recommend that regular clinical and radiological examinations be performed in these individuals to accurately evaluate the risk of CVD. Full article

Perfusion asymmetries have been associated with vascular pathology. Physical activity is a component of vascular health. Here, we investigate the impact of a thirty-day regular home-based physical activity program in older individuals with multiple age-related comorbidities. Eleven participants of both sexes were included. Skin perfusion was assessed in both feet by laser Doppler flowmetry (LDF, for deeper perfusion) and polarized light spectroscopy (PSp, for superficial perfusion). At baseline, participants had significant perfusion differences between right and left feet (p = 0.005 with LDF; p = 0.028 with PSp), which disappeared with activity and reappeared in recovery. After 30 days, both feet showed significant perfusion increases as assessed with LDF (p = 0.005) compared to D0. At this point, the perfusion asymmetry observed at D0 was no longer present. However, the superficial perfusion asymmetry assessed by PSp persisted at D30 (p = 0.028). Data show that regular physical activity positively altered the lower limb perfusion pattern. Systolic pressure and mean arterial pressure were also significantly reduced at D30. These impacts seem to be directly related to the physical activity program introduced in the day-by-day routines of these participants. These also encourage further research on the role of symmetry–asymmetry in prevention, treatment, and rehabilitation in vascular medicine. Full article

Background: Sleep is essential for health, especially during adolescence. However, most adolescents do not obtain the recommended 8 to 10 h of sleep, and their health is significantly affected. While both physical activity (PA) and diet have been shown to help improve the sleep quality and duration, the combined association of these two factors with sleep has yet to be analysed. Objectives: Therefore, the main objective of this study was to assess the evidence on the combined association of PA and diet with the quality and duration of sleep in adolescents. Secondary objectives were to analyse the evidence on the single association of PA with the quality and duration of sleep in adolescents and to analyse the single association of diet with the quality and duration of sleep in adolescents. Methods: To this end, a scoping review was conducted with a structured search in four online databases (PubMed, Scopus, Web of Science and ERIC). Results: The findings suggest that the amount of PA (time/week) and healthy dietary patterns, characterised by meal regularity and high consumption of fruits and vegetables, favour a better quality and a longer duration of sleep. Conversely, less weekly PA and the intake of less healthy foods, such as ultra-processed foods, are associated with decreasing the sleep quality and duration. Conclusions: In conclusion, the results underscore the importance of considering PA and diet as an appropriate approach to investigating sleep quality and duration in adolescents. Studies analysing the interplay between PA, diet and sleep in adolescents are scarce. Full article

The meshless displacement error-recovery parametric investigation in finite element method-based incompressible elastic analysis is presented in this study. It investigates key parameters such as interpolation schemes, patch configurations, dilation indexes, weight functions, and meshing patterns. The study evaluates error recovery effectiveness (local and global), convergence rates, and adaptive mesh improvement for triangular/quadrilateral discretization schemes. It uses meshless moving least squares (MLS) interpolation with rectangular and circular support regions and solves benchmark plate and cylinder problems. It is observed that a circular influence region, a cubic spline weight function, and regular mesh patterns yield a better performance of than an MLS-based error recovery method. The study also concludes that lower dilation index values with rectangular influence regions are preferable for regular meshes, while higher dilation index values with radial influence regions are suitable for preferable meshes to enhance MLS error recovery. Full article

Modern power systems are high-dimensional, strongly coupled nonlinear systems with complex and diverse dynamic characteristics. The polynomial model of the power system is a key focus in stability research. Therefore, this paper presents a study on the approximate transient stability solution targeting the fault process in power systems. Firstly, based on the inherent sinusoidal coupling characteristics of the power system swing equations, a generalized polynomial matrix description in perturbation form is presented using the Taylor expansion formula. Secondly, considering the staged characteristics of the stability process in power systems, the approximate solutions of the polynomial model during and after the fault are provided using coordinate transformation and regular perturbation techniques. Then, the structural characteristics of the approximate solutions are analyzed, revealing the mathematical basis of the stable motion patterns of the power grid, and a monotonicity rule of the system’s power angle oscillation amplitude is discovered. Finally, the effectiveness of the proposed methods and analyses is further validated by numerical examples of the IEEE 3-machine 9-bus system and IEEE 10-machine 39-bus system. Full article

Nitrogen (N) fertilization promotes morphofunctional attributes that enhance plant performance under stress conditions, but the amount and form supplied modify the magnitude of plant responses. We assessed several morpho-physiological and biochemical responses of Prosopis laevigata seedlings to a high supply of N, provided as either inorganic (NH₄NO₃) or organic (amino acids). Such N treatments were applied on four-month-old seedlings as a supplement of 90 mg N to a regular supply of 274 mg N plant⁻¹. Nitrogen supply modified biomass allocation patterns between leaves and roots regardless of N form. Increased N input decreased photosynthetic capacity, even when plants had high internal N reserves. Organic N fertilization reduced the N use efficiency, but increased leaf and root amino acid concentrations. Proteins accumulated in stems in plants receiving inorganic N, while the organic N increased leaf proteins. High N supply promoted root starch accumulation irrespective of N form. Nitrogen supply did not directly influence plants’ regrowth capacity. Still, resprouting was correlated to initial root-to-shoot ratios and root starch, confirming the importance of roots as storage reserves of starch for recovering biomass after browsing. These findings have practical implications for designing nutritional management strategies in nurseries to improve seedling performance in afforestation efforts. Full article

Recent studies revealed anomalous underscreening in concentrated electrolytes, and we suggest that the underscreened electrostatic forces between membrane proteins play a significant role in the process of self-assembly. In this work, we assumed that the underscreened electrostatic forces compete with the thermodynamic Casimir forces induced by concentration fluctuations in the lipid bilayer, and developed a simplified model for a binary mixture of oppositely charged membrane proteins with different preference to liquid-ordered and liquid-disordered domains in the membrane. In the model, like macromolecules interact with short-range Casimir attraction and long-range electrostatic repulsion, and the cross-interaction is of the opposite sign. We determine energetically favored patterns in a system in equilibrium with a bulk reservoir of the macromolecules. Different patterns consisting of clusters and stripes of the two components and of vacancies are energetically favorable for different values of the chemical potentials. Effects of thermal flutuations at low temperature are studied using Monte Carlo simulations in grand canonical and canonical ensembles. For fixed numbers of the macromolecules, a single two-component cluster with a regular pattern coexists with dispersed small one-component clusters, and the number of small clusters depends on the ratio of the numbers of the molecules of the two components. Our results show that the pattern formation is controlled by the shape of the interactions, the density of the proteins, and the proportion of the components. Full article

The period ratio and the drift ratio are commonly used as plane regularity control indices for multi-story buildings. However, they fail to reasonably reflect the regularity of lateral force-resisting component configuration and deformation characteristics in non-rigid plate bent frame structures. This study focuses on the analysis of non-rigid single-span bent frames, examining the variation patterns of a suitable regularity index for non-rigid plate bent frame structures, referred to as the shear force lateral stiffness matching index, under various parameters. Additionally, it introduces indices to quantify the deformation response of non-rigid plate bent frame structures, providing a detailed analysis of the impact of factors such as eccentricity, torsional stiffness, and roof slab stiffness on the deformation characteristics of non-rigid plate bent frame structures and the shear force lateral stiffness matching index. The results show that the shear force lateral stiffness matching index can reflect the inconsistency in the horizontal displacement response of lateral force-resisting components caused by deformations in the roof slab. The proposed indices for torsional and bending deformations accurately quantify the roof slab’s deformation response, revealing the horizontal deformation characteristics of lateral force-resisting components in non-rigid frames. When eccentricity is present, the stiffness of the roof slab has a non-monotonic effect on the torsional component of the structural seismic response. Full article

Within the context of Indian religions, Jainism has long been recognized for its extensive use of permutations and combinations. However, the application of these principles within Buddhist scriptures has received relatively little scholarly attention. This paper introduces a new example of the specific application of permutations and combinations in Buddhist scriptures. In this paper, we focus on the first saṅghādisesa rule in the Theravāda-vinaya, which lists a series of element sets and arranges these elements according to a certain pattern known as “ten-roots” (mūla), and we discover that these arrangements form a regular numerical sequence, called “oblong numbers”. Moreover, similar patterns with different quantities are also found in the fourth Pārājika and the fifth saṅghādisesa rules. This indicates that the compilers of the Theravāda-vinaya did not use this mathematical knowledge without basis. Interestingly, we also found the use of this sequence in the Bakhshālī manuscript. Therefore, in this article, after summarizing and verifying the arrangement rules of the Theravāda-vinaya, we discuss whether the oblong numbers were influenced by Greek mathematics. Full article

Convolutional Neural Networks (CNNs) are among the most prevalent deep learning techniques employed across various domains. The computational complexity of CNNs is largely attributed to the convolution operations. These operations are computationally demanding and significantly impact overall model performance. Traditional CNN implementations convert convolutions into matrix operations via the im2col (image to column) technique, facilitating parallelization through advanced BLAS libraries. This study identifies and investigates a significant yet intricate pattern of data redundancy within the matrix-based representation of convolutions, a pattern that, while complex, presents opportunities for optimization. Through meticulous analysis of the redundancy inherent in the im2col approach, this paper introduces a mathematically succinct matrix representation for convolution, leading to the development of an optimized FFT-based convolution with finer FFT granularity. Benchmarking demonstrates that our approach achieves an average speedup of 14 times and a maximum speedup of 17 times compared to the regular FFT convolution. Similarly, it outperforms the Im2col+GEMM approach from NVIDIA’s cuDNN library, achieving an average speedup of three times and a maximum speedup of five times. Our FineGrained FFT convolution approach, when integrated into Caffe, a widely used deep learning framework, leads to significant performance gains. Evaluations using synthetic CNNs designed for real-world applications show an average speedup of 1.67 times. Furthermore, a modified VGG network variant achieves a speedup of 1.25 times. Full article

The interplay effect is a challenge when using proton scanning beams for the treatment of thoracic and abdominal cancers. The aim of this study was to evaluate the facility-specific interplay effect in terms of dose distortion and irradiation time for different beam delivery modalities, including free breathing (FB) irradiation, rescanning, deep inspiration breath-hold (DIBH), and respiratory gating. This study was carried out at a synchrotron-based facility with spot-scanning beam delivery. A motion phantom with a radiochromic film was used to measure dose distributions. Regular and irregular motion patterns were studied. Dose homogeneity and the gamma index were calculated to quantify the interplay effect. The interplay effect significantly decreased the homogeneity and gamma passing rate by 12% and 46%, respectively, when FB irradiation without motion mitigation was used for 20 mm peak-to-peak motion. Rescanning and DIBH partially mitigated the distortions but doubled the irradiation time, while gating provided the superior dose distribution with only a 25% increase in time compared to FB irradiation without mitigation. The interplay effect was a function of motion amplitude and varied with the beam delivery modality. Gating may be a more preferable technique for the synchrotron-based facility in terms of minimizing dose distortion and treatment time. Full article

Introducing grain legumes, i.e., pulses, into any food pattern effectively increases dietary fiber and other bioactive food components of public health concern; however, the impact depends on the amount consumed. Given the convergence of preclinical and clinical data indicating that intake of at least 300 g (1.5 cup) of cooked pulse per day has clinically observable benefit, the feasibility for a typical consumer was demonstrated by creation of a fourteen-day menu plan that met this criterion. This menu plan, named Bean Cuisine, was comprised of a combination of five cooked pulses: dry beans, chickpeas, cowpeas, dry peas, and lentils. As reported herein, the impact of each menu day of the fourteen-day plan on gut microbial composition and predicted function was evaluated in female C57BL/6J mice, a strain commonly used in studies of metabolic dysfunction-associated chronic diseases. We report that pulse-related effects were observed across a wide variety of food item combinations. In comparison to a pulse-free human cuisine, all pulse menu days enriched for a gut ecosystem were associated with changes in predicted metabolic pathways involving amino acids (lysine, tryptophan, cysteine), short-chain fatty acids (butyrate, acetate), and vitamins (B₁, B₆, B₉, B₁₂, K₂) albeit via different combinations of microbiota, according to the PICRUSt2 estimates. The predicted metabolic functions correlating with the various pulses in the menus, indicate the value of a food pattern comprised of all pulse types consumed on a regular basis. This type of multi-pulse food pattern has the potential to enhance the taxonomic and functional diversity of the gut microbiome as a means of strengthening the resilience of the gut ecosystem to the challenges associated with the daily activities of living. Full article

Suicidal ideation is a process that is intertwined with suicidal behavior. It begins with the formation of an idea about whether it is worth continuing to live, an idea that can evolve and trigger a series of actions ranging from planning to the execution of the suicidal act. This is a descriptive observational study based on numerical measurements with its respective statistical analysis that established the behavioral patterns of the phenomenon studied. The research proposal was approved by the research committee of the Faculty of Medicine and Surgery, URSE; data collection was performed through the instruments: Beck Suicidal Ideation Scale, Beck Depression Inventory, Abbreviated Scale of School Bullying Questionnaire, Drug Dependence Identification Questionnaire, and Family Apgar. The prevalence of suicidal ideation was 5.4%; 19.7% of the medical students have been victims of bullying in any form; 22.2% reported regular use of alcohol, tobacco, drugs, and other addictive substances; in addition, 17.7% had mild family dysfunction, moderate in 9.9% and severe with 15.3%; depression was recorded to a mild degree with 6.4%, followed by moderate in 1.5% of cases. Suicidal ideation among medical students is of concern; these problems must be addressed comprehensively, promoting a supportive environment that promotes the mental health and well-being of medical students. Full article