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Search Results (844)

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Keywords = ultrasonic signals

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16 pages, 14457 KiB  
Article
ScAlN PMUTs Based on Flexurally Suspended Membrane for Long-Range Detection
by Shutao Yao, Wenling Shang, Guifeng Ta, Jinyan Tao, Haojie Liu, Xiangyong Zhao, Jianhe Liu, Bin Miao and Jiadong Li
Micromachines 2024, 15(11), 1377; https://doi.org/10.3390/mi15111377 - 14 Nov 2024
Viewed by 242
Abstract
Piezoelectric micromachined ultrasonic transducers (PMUTs) have been widely applied in distance sensing applications. However, the rapid movement of miniature robots in complex environments necessitates higher ranging capabilities from sensors, making the enhancement of PMUT sensing distance critically important. In this paper, a scandium-doped [...] Read more.
Piezoelectric micromachined ultrasonic transducers (PMUTs) have been widely applied in distance sensing applications. However, the rapid movement of miniature robots in complex environments necessitates higher ranging capabilities from sensors, making the enhancement of PMUT sensing distance critically important. In this paper, a scandium-doped aluminum nitride (ScAlN) PMUT based on a flexurally suspended membrane is proposed. Unlike the traditional fully clamped design, the PMUT incorporates a partially clamped membrane, thereby extending the vibration displacement and enhancing the output sound pressure. Experimental results demonstrate that at a resonant frequency of 78 kHz, a single PMUT generates a sound pressure level (SPL) of 112.2 dB at a distance of 10 mm and achieves a high receiving sensitivity of 12.3 mV/Pa. Distance testing reveals that a single PMUT equipped with a horn can achieve a record-breaking distance sensing range of 11.2 m when used alongside a device capable of simultaneously transmitting and receiving ultrasound signals. This achievement is significant for miniaturized and integrated applications that utilize ultrasound for long-range target detection. Full article
(This article belongs to the Special Issue MEMS Ultrasonic Transducers)
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12 pages, 4110 KiB  
Article
Wavelength Locking and Calibration of Fiber-Optic Ultrasonic Sensors Using Single-Sideband-Modulated Laser
by Mohammed Alshammari and Ming Han
Photonics 2024, 11(11), 1063; https://doi.org/10.3390/photonics11111063 - 13 Nov 2024
Viewed by 290
Abstract
Implementation of edge-filter detection for interrogating optical interferometric ultrasonic sensors is often hindered by the lack of cost-effective laser sources with agile wavelength tunability and good noise performance. The detected signal can also be affected by optical power variations and locking-point drift, negatively [...] Read more.
Implementation of edge-filter detection for interrogating optical interferometric ultrasonic sensors is often hindered by the lack of cost-effective laser sources with agile wavelength tunability and good noise performance. The detected signal can also be affected by optical power variations and locking-point drift, negatively affecting the sensor accuracy. Here, we report the use of laser single-sideband generation with a dual-parallel Mach–Zehnder interferometer (DP-MZI) for laser wavelength tuning and locking in edge-filter detection of fiber-optic ultrasonic sensors. We also demonstrate real-time in situ calibration of the sensor response to ultrasound-induced wavelength shift tuning. The DP-MZI is employed to generate a known wavelength modulation of the laser, whose response is used to gauge the sensor response to the ultrasound-induced wavelength shifts in real time and in situ. Experiments were performed on a fiber-optic ultrasonic sensor based on a high-finesse Fabry–Perot interferometer formed by two fiber Bragg gratings. The results demonstrated the effectiveness of the laser locking against laser wavelength drift and temperature variations and the effectiveness of the calibration method against optical power variations and locking-point drift. These techniques can enhance the operational robustness and increase the measurement accuracy of optical ultrasonic sensors. Full article
(This article belongs to the Special Issue Recent Research on Optical Sensing and Precision Measurement)
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14 pages, 2271 KiB  
Article
Location Detection and Numerical Simulation of Guided Wave Defects in Steel Pipes
by Hao Liang, Junhong Zhang and Song Yang
Appl. Sci. 2024, 14(22), 10403; https://doi.org/10.3390/app142210403 - 12 Nov 2024
Viewed by 372
Abstract
At present, researchers in the field of pipeline inspection focus on pipe wall defects while neglecting pipeline defects in special situations such as welds. This poses a threat to the safe operation of projects. In this paper, a multi-node fusion and modal projection [...] Read more.
At present, researchers in the field of pipeline inspection focus on pipe wall defects while neglecting pipeline defects in special situations such as welds. This poses a threat to the safe operation of projects. In this paper, a multi-node fusion and modal projection algorithm of steel pipes based on guided wave technology is proposed. Through an ANSYS numerical simulation, research is conducted to achieve the identification, localization, and quantification of axial cracks on the surface of straight pipelines and internal cracks in circumferential welds. The propagation characteristics and vibration law of ultrasonic guided waves are theoretically solved by the semi-analytical finite element method in the pipeline. The model section is discretized in one-dimensional polar coordinates to obtain the dispersion curve of the steel pipe. The T(0,1) mode, which is modulated by the Hanning window, is selected to simulate the axial crack of the pipeline and the L(0,2) mode to simulate the crack in the weld, and the correctness of the dispersion curve is verified. The results show that the T(0,1) and L(0,2) modes are successfully excited, and they are sensitive to axial and circumferential cracks. The time–frequency diagram of wavelet transform and the time domain diagram of the crack signal of Hilbert transform are used to identify the echo signal. The first wave packet peak point and group velocity are used to locate the crack. The pure signal of the crack is extracted from the simulation data, and the variation law between the reflection coefficient and the circumferential and radial dimensions of the defect is calculated to evaluate the size of the defect. This provides a new and feasible method for steel pipe defect detection. Full article
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14 pages, 8120 KiB  
Article
The Influence of Coaxial Ultrasound on the Droplet Transfer of High Nitrogen Steel GMAW Process
by Jiawen Luo, Zhizheng He, Zeng Liu, Zihuan Hua, Bin Teng and Chenglei Fan
Materials 2024, 17(22), 5509; https://doi.org/10.3390/ma17225509 - 12 Nov 2024
Viewed by 267
Abstract
The nitrogen bubble bursting phenomenon during the welding process of high nitrogen steel (HNS) can lead to unstable droplet transfer and welding process, reducing the quality of weld formation. In this study, a novel approach, ultrasonic-assisted gas metal arc welding (U-GMAW), is proposed [...] Read more.
The nitrogen bubble bursting phenomenon during the welding process of high nitrogen steel (HNS) can lead to unstable droplet transfer and welding process, reducing the quality of weld formation. In this study, a novel approach, ultrasonic-assisted gas metal arc welding (U-GMAW), is proposed to suppress the escape of nitrogen gas during droplet transfer. This study investigates the influence of ultrasound on the metal transfer process during two distinct metal transfer modes: short-circuiting and droplet transfer. Ultrasound has a significant effect on the welding process; as ultrasonic power increases, both the arc length and droplet size decrease, while the droplet transfer frequency increases and the electrical signal stabilizes. Under the experimental conditions of this study, ultrasound has the most effective improvement on the metal transfer behavior when the ultrasonic power reaches 2 kW. Ultrasound enhances the stability of the droplet transfer process, making U-GMAW an effective and novel approach for controlling the droplet transfer behavior of high nitrogen steel. Full article
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13 pages, 4201 KiB  
Article
Convolutional Neural Network for Interface Defect Detection in Adhesively Bonded Dissimilar Structures
by Damira Smagulova, Vykintas Samaitis and Elena Jasiuniene
Appl. Sci. 2024, 14(22), 10351; https://doi.org/10.3390/app142210351 - 11 Nov 2024
Viewed by 352
Abstract
This study presents an ultrasonic non-destructive method with convolutional neural networks (CNN) used for the detection of interface defects in adhesively bonded dissimilar structures. Adhesive bonding, as the weakest part of such structures, is prone to defects, making their detection challenging due to [...] Read more.
This study presents an ultrasonic non-destructive method with convolutional neural networks (CNN) used for the detection of interface defects in adhesively bonded dissimilar structures. Adhesive bonding, as the weakest part of such structures, is prone to defects, making their detection challenging due to various factors, including surface curvature, which causes amplitude variations. Conventional non-destructive methods and processing algorithms may be insufficient to enhance detectability, as some influential factors cannot be fully eliminated. Even after aligning signals reflected from the sample surface and interface, in some cases, due to non-parallel interfaces, persistent amplitude variations remain, significantly affecting defect detectability. To address this problem, a proposed method that integrates ultrasonic NDT and CNN, and which is able to recognize complex patterns and non-linear relationships, is developed in this work. Traditional ultrasonic pulse-echo testing was performed on adhesive structures to collect experimental data and generate C-scan images, covering the time gate from the first interface reflection to the time point where the reflections were attenuated. Two classes of datasets, representing defective and defect-free areas, were fed into the neural network. One subset of the dataset was used for model training, while another subset was used for model validation. Additionally, data collected from a different sample during an independent experiment were used to evaluate the generalization and performance of the neural network. The results demonstrated that the integration of a CNN enabled high prediction accuracy and automation of the analysis process, enhancing efficiency and reliability in detecting interface defects. Full article
(This article belongs to the Special Issue New Technology Trends in Smart Sensing)
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14 pages, 8818 KiB  
Article
Evaluation of the Influence of Surface Roughness Parameters on Ultrasonic Rayleigh Waveforms
by Karol Grochalski, Jakub Kowalczyk, Marian Jósko and Michal Wieczorowski
Materials 2024, 17(22), 5493; https://doi.org/10.3390/ma17225493 - 11 Nov 2024
Viewed by 399
Abstract
Ultrasonic nondestructive testing is widely used not only in the laboratory, but also in industry. The tests use various types of ultrasonic waves, diverse measurement techniques and different apparatus. One of the problems encountered is the high susceptibility of the surface wave to [...] Read more.
Ultrasonic nondestructive testing is widely used not only in the laboratory, but also in industry. The tests use various types of ultrasonic waves, diverse measurement techniques and different apparatus. One of the problems encountered is the high susceptibility of the surface wave to interference. Some of the interference is random in nature and can be minimized (e.g., contamination of the surface or resting a finger on the surface under study). Some of the interference is permanent in nature, such as variable surface roughness. The aim of the conducted research was to evaluate the influence of roughness on ultrasonic wave propagation. The study used samples with surface roughness Sa from 0.28 to 219 µm, and ultrasonic surface wave probes with frequencies from 1.41 to 8.02 MHz. It was observed that roughness significantly affects the attenuation of the ultrasonic wave, and the differences in signal amplification reached more than 15 dB. Similarly, the effect of the ultrasonic wave’s transit time through surfaces of different roughness was noted. It was found that the difference in the ultrasonic wave transition time was more than 50 µs. The results of the study can be helpful for the ultrasonic testing of materials with different surface conditions. Full article
(This article belongs to the Special Issue Sensing and Monitoring Technologies in Composite Materials)
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23 pages, 2249 KiB  
Article
Improved EMAT Sensor Design for Enhanced Ultrasonic Signal Detection in Steel Wire Ropes
by Immanuel Rossteutscher, Oliver Blaschke, Florian Dötzer, Thorsten Uphues and Klaus Stefan Drese
Sensors 2024, 24(22), 7114; https://doi.org/10.3390/s24227114 - 5 Nov 2024
Viewed by 522
Abstract
This study is focused on optimizing electromagnetic acoustic transducer (EMAT) sensors for enhanced ultrasonic guided wave signal generation in steel cables using CAD and modern manufacturing to enable contactless ultrasonic signal transmission and reception. A lab test rig with advanced measurement and data [...] Read more.
This study is focused on optimizing electromagnetic acoustic transducer (EMAT) sensors for enhanced ultrasonic guided wave signal generation in steel cables using CAD and modern manufacturing to enable contactless ultrasonic signal transmission and reception. A lab test rig with advanced measurement and data processing was set up to test the sensors’ ability to detect cable damage, like wire breaks and abrasion, while also examining the effect of potential disruptors such as rope soiling. Machine learning algorithms were applied to improve the damage detection accuracy, leading to significant advancements in magnetostrictive measurement methods and providing a new standard for future development in this area. The use of the Vision Transformer Masked Autoencoder Architecture (ViTMAE) and generative pre-training has shown that reliable damage detection is possible despite the considerable signal fluctuations caused by rope movement. Full article
(This article belongs to the Special Issue Feature Papers in Physical Sensors 2024)
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20 pages, 12059 KiB  
Article
Fast and Smart State Characterization of Large-Format Lithium-Ion Batteries via Phased-Array Ultrasonic Sensing Technology
by Zihan Zhou, Wen Hua, Simin Peng, Yong Tian, Jindong Tian and Xiaoyu Li
Sensors 2024, 24(21), 7061; https://doi.org/10.3390/s24217061 - 1 Nov 2024
Viewed by 576
Abstract
Lithium-ion batteries (LIBs) are widely used in electric vehicles and energy storage systems, making accurate state transition monitoring a key research topic. This paper presents a characterization method for large-format LIBs based on phased-array ultrasonic technology (PAUT). A finite element model of a [...] Read more.
Lithium-ion batteries (LIBs) are widely used in electric vehicles and energy storage systems, making accurate state transition monitoring a key research topic. This paper presents a characterization method for large-format LIBs based on phased-array ultrasonic technology (PAUT). A finite element model of a large-format aluminum shell lithium-ion battery is developed on the basis of ultrasonic wave propagation in multilayer porous media. Simulations and comparative analyses of phased array ultrasonic imaging are conducted for various operating conditions and abnormal gas generation. A 40 Ah ternary lithium battery (NCMB) is tested at a 0.5C charge-discharge rate, with the state of charge (SOC) and ultrasonic data extracted. The relationship between ultrasonic signals and phased array images is established through simulation and experimental comparisons. To estimate the SOC, a fully connected neural network (FCNN) model is designed and trained, achieving an error of less than 4%. Additionally, phased array imaging, which is conducted every 5 s during overcharging and overdischarging, reveals that gas bubbles form at 0.9 V and increase significantly at 0.2 V. This research provides a new method for battery state characterization. Full article
(This article belongs to the Section Electronic Sensors)
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15 pages, 5501 KiB  
Article
Recognition of Heat-Damaged Corn Seeds Based on Fusion of Laser Ultrasonic Signal and Infrared Image Features
by Tao Lu, Zihua Wang, Zhongyi Zhao and Zhike Zhao
Agronomy 2024, 14(11), 2567; https://doi.org/10.3390/agronomy14112567 - 1 Nov 2024
Viewed by 479
Abstract
Corn is widely cultivated on a global scale. However, high temperatures during storage and transportation can lead to thermal damage to the kernels, negatively impacting their quality. Traditional methods for identifying heat-damaged grains primarily rely on manual inspection, which is characterized by low [...] Read more.
Corn is widely cultivated on a global scale. However, high temperatures during storage and transportation can lead to thermal damage to the kernels, negatively impacting their quality. Traditional methods for identifying heat-damaged grains primarily rely on manual inspection, which is characterized by low efficiency and accuracy. This study proposes a novel identification method that integrates laser ultrasonic signals with infrared image texture features. A pulsed laser stimulates the seeds to generate laser ultrasonic signals, while an infrared camera captures infrared images of the seeds. We extract time-domain, frequency-domain, and Hilbert-domain features from the laser ultrasonic signals, in addition to texture features from the infrared images. These features are combined using Canonical Correlation Analysis (CCA). Subsequently, the fused features are classified using a Backpropagation (BP) neural network, Support Vector Machine (SVM), and Particle Swarm Optimization–Support Vector Machine (PSO–SVM). The results indicate that the recognition rate achieved with the fused ‘signal-image’ features reaches 99.17%, providing a novel approach for detecting heat-damaged corn seeds. Full article
(This article belongs to the Section Precision and Digital Agriculture)
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12 pages, 2930 KiB  
Article
Ultrasonic A-Scan Signals Data Augmentation Using Electromechanical System Modelling to Enhance Cataract Classification Methods
by Mário J. Santos, Lorena I. Petrella, Fernando Perdigão and Jaime Santos
Electronics 2024, 13(21), 4144; https://doi.org/10.3390/electronics13214144 - 22 Oct 2024
Viewed by 463
Abstract
The use of artificial intelligence in diverse diagnosis areas has significantly increased in the past few years because of the advantages it represents in clinical routine. Among the diverse diagnostic techniques, the use of ultrasounds is often preferred because of their simplicity, low [...] Read more.
The use of artificial intelligence in diverse diagnosis areas has significantly increased in the past few years because of the advantages it represents in clinical routine. Among the diverse diagnostic techniques, the use of ultrasounds is often preferred because of their simplicity, low cost, non-invasiveness, and non-ionizing characteristic. However, obtaining an adequate number of patients and data for training and testing machine learning models is challenging. To overcome this limitation, a novel approach is proposed for simulating data produced by ultrasonic diagnostic devices. The implemented method was based on a clinical prototype for eye cataract diagnosis, although the method can be extended to other applications as well. The proposed model encompasses the electric-to-acoustic signal conversion in the ultrasonic transducer, the wave propagation through the biological medium, and the subsequent acoustic-to-electric signal conversion in the transducer. Electrical modelling of the transducer was performed using a two-port network approach, while the acoustic wave propagation was modelled by using the k-Wave MATLAB toolbox. It was verified that the holistic modelling approach enabled the generation of synthetic data augmentation, presenting high similarity with real data. Full article
(This article belongs to the Special Issue Feature Papers in Circuit and Signal Processing)
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22 pages, 61613 KiB  
Article
Ultrasonic Array-Based Multi-Source Fusion Indoor Positioning Technology
by Cong Li, Chenning Zhang, Bing Chen, Shaojian Xu, Luping Xu and Bo Yan
Sensors 2024, 24(20), 6641; https://doi.org/10.3390/s24206641 - 15 Oct 2024
Viewed by 568
Abstract
Underground mining involves numerous risks, such as collapses, gas leaks, and explosions, posing significant threats to worker safety. In this work, we develop an indoor localization system that uses Bluetooth for coarse positioning and ultrasonic arrays for precision calibration. This system is particularly [...] Read more.
Underground mining involves numerous risks, such as collapses, gas leaks, and explosions, posing significant threats to worker safety. In this work, we develop an indoor localization system that uses Bluetooth for coarse positioning and ultrasonic arrays for precision calibration. This system is particularly useful for automated mining operations in underground environments where satellite positioning signals are unavailable. The indoor localization system consists of ultrasonic receiver arrays and an improved multi-transmitter-multi-receiver algorithm, enabling accurate localization within the mining environment. Geometric Dilution of Precision (GDOP) analysis is incorporated to optimize the network layout, and an inertial navigation module is integrated to track the posture of moving objects, enabling precise trajectory determination over large areas, such as coal mines. In the experiment, three traditional methods were compared, and the proposed tracking approach demonstrated a positioning accuracy within 10 cm, reducing error by 20% compared to conventional techniques. This high-precision indoor localization method proves beneficial for underground mining applications. Full article
(This article belongs to the Section Navigation and Positioning)
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21 pages, 4961 KiB  
Article
Low-Cost Device for Measuring Wastewater Flow Rate in Open Channels
by Daria Wotzka and Dariusz Zmarzły
Sensors 2024, 24(20), 6607; https://doi.org/10.3390/s24206607 - 14 Oct 2024
Viewed by 611
Abstract
This research paper describes the development of a low-cost device for measuring wastewater flow rates in open channels, a significant advancement enabled by the evolution of microcomputers and processing techniques. A laboratory setup was constructed to validate the device’s accuracy against a standard [...] Read more.
This research paper describes the development of a low-cost device for measuring wastewater flow rates in open channels, a significant advancement enabled by the evolution of microcomputers and processing techniques. A laboratory setup was constructed to validate the device’s accuracy against a standard flow measurement method, optimizing key parameters to achieve a linear relationship between detected and set flow rates, while considering hardware limitations and energy efficiency. The central focus of the research was developing a method to measure the velocity of contaminated fluid using ultrasonic signals, employing the cross-correlation method for signal delay analysis in a stochastic environment. This was complemented by a procedure to measure fluid levels, also based on ultrasonic signals. The device’s reliability was assessed through repeatability and uncertainty measurements, confirming its accuracy with an extended uncertainty not exceeding an average of 3.47% for flows above 40 L/min. The device has potential to provide valuable data on the operational dynamics of sanitary networks, crucial for developing and calibrating simulation models. Full article
(This article belongs to the Section Industrial Sensors)
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14 pages, 5623 KiB  
Article
Ultrasonic Guided Wave Health Monitoring of High-Temperature Aircraft Structures Based on Variational Mode Decomposition and Fuzzy Entropy
by Feiting Zhang, Kaifu Zhang, Hui Cheng, Dongyue Gao and Keyi Cai
Actuators 2024, 13(10), 411; https://doi.org/10.3390/act13100411 - 12 Oct 2024
Viewed by 454
Abstract
This paper presents an innovative approach to high-temperature health monitoring of aircraft structures utilizing an ultrasonic guided wave transmission and reception system integrated with a zirconia heat buffer layer. Aiming to address the challenges posed by environmental thermal noise and the installation of [...] Read more.
This paper presents an innovative approach to high-temperature health monitoring of aircraft structures utilizing an ultrasonic guided wave transmission and reception system integrated with a zirconia heat buffer layer. Aiming to address the challenges posed by environmental thermal noise and the installation of heat buffers, which can introduce structural nonlinearities into guided wave signals, a composite guided wave consisting of longitudinal and Lamb waves was proposed for online damage detection within thermal protection systems. To effectively analyze these complex signals, a hybrid damage monitoring technique combining variational mode decomposition (VMD) and fuzzy entropy (FEN) was introduced. The VMD was employed to isolate the principal components of the guided wave signals, while the fuzzy entropy of these components served as a quantitative damage factor, characterizing the extent of the structural damage. Furthermore, this study validated the feasibility of piezoelectric probes equipped with heat buffer layers for both exciting and receiving ultrasonic guided wave signals in a dual heat buffer layer, a one-transmit-one-receive configuration. The experimental results demonstrated the efficacy of the proposed VMD-FEN damage factor for real-time monitoring of damage in aircraft thermal protection systems, both at ambient and elevated temperatures (up to 150 °C), showcasing its potential for enhancing the safety and reliability of aerospace structures operating under extreme thermal conditions. Full article
(This article belongs to the Section Aircraft Actuators)
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19 pages, 9136 KiB  
Article
A Novel Ultrasonic Leak Detection System in Nuclear Power Plants Using Rigid Guide Tubes with FCOG and SNR
by You-Rak Choi, Doyeob Yeo, Jae-Cheol Lee, Jai-Wan Cho and Sangook Moon
Sensors 2024, 24(20), 6524; https://doi.org/10.3390/s24206524 - 10 Oct 2024
Viewed by 863
Abstract
Leak detection in nuclear reactor coolant systems is crucial for maintaining the safety and operational integrity of nuclear power plants. Traditional leak detection methods, such as acoustic emission sensors and spectroscopy, face challenges in sensitivity, response time, and accurate leak localization, particularly in [...] Read more.
Leak detection in nuclear reactor coolant systems is crucial for maintaining the safety and operational integrity of nuclear power plants. Traditional leak detection methods, such as acoustic emission sensors and spectroscopy, face challenges in sensitivity, response time, and accurate leak localization, particularly in complex piping systems. In this study, we propose a novel leak detection approach that incorporates a rigid guide tube into the insulation layer surrounding reactor coolant pipes and combines this with an advanced detection criterion based on Frequency Center of Gravity shifts and Signal-to-Noise Ratio analysis. This dual-method strategy significantly improves the sensitivity and accuracy of leak detection by providing a stable transmission path for ultrasonic signals and enabling robust signal analysis. The rigid guide tube-based system, along with the integrated criteria, addresses several limitations of existing technologies, including the detection of minor leaks and the complexity of installation and maintenance. By enhancing the early detection of leaks and enabling precise localization, this approach contributes to increased reactor safety, reduced downtime, and lower operational costs. Experimental evaluations demonstrate the system’s effectiveness, focusing on its potential as a valuable addition to the current array of nuclear power plant maintenance technologies. Future research will focus on optimizing key parameters, such as the threshold frequency shift (Δf) and the number of randomly selected frequencies (N), using machine learning techniques to further enhance the system’s accuracy and reliability in various reactor environments. Full article
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14 pages, 1903 KiB  
Review
Recent Advancements in High-Frequency Ultrasound Applications from Imaging to Microbeam Stimulation
by Min Gon Kim, Changhan Yoon and Hae Gyun Lim
Sensors 2024, 24(19), 6471; https://doi.org/10.3390/s24196471 - 8 Oct 2024
Viewed by 1414
Abstract
Ultrasound is a versatile and well-established technique using sound waves with frequencies higher than the upper limit of human hearing. Typically, therapeutic and diagnosis ultrasound operate in the frequency range of 500 kHz to 15 MHz with greater depth of penetration into the [...] Read more.
Ultrasound is a versatile and well-established technique using sound waves with frequencies higher than the upper limit of human hearing. Typically, therapeutic and diagnosis ultrasound operate in the frequency range of 500 kHz to 15 MHz with greater depth of penetration into the body. However, to achieve improved spatial resolution, high-frequency ultrasound (>15 MHz) was recently introduced and has shown promise in various fields such as high-resolution imaging for the morphological features of the eye and skin as well as small animal imaging for drug and gene therapy. In addition, high-frequency ultrasound microbeam stimulation has been demonstrated to manipulate single cells or microparticles for the elucidation of physical and functional characteristics of cells with minimal effect on normal cell physiology and activity. Furthermore, integrating machine learning with high-frequency ultrasound enhances diagnostics, including cell classification, cell deformability estimation, and the diagnosis of diabetes and dysnatremia using convolutional neural networks (CNNs). In this paper, current efforts in the use of high-frequency ultrasound from imaging to stimulation as well as the integration of deep learning are reviewed, and potential biomedical and cellular applications are discussed. Full article
(This article belongs to the Special Issue Ultrasonic Imaging and Sensors II)
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