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8 pages, 6736 KiB  
Proceeding Paper
Computational Analysis of Different Stiffener Designs for Power Transformer Tank Walls
by Md Milon Hasan, Asif Islam and Mohammad Abu Hasan Khondoker
Eng. Proc. 2024, 76(1), 57; https://doi.org/10.3390/engproc2024076057 - 29 Oct 2024
Viewed by 324
Abstract
While power transformer manufacturers are well versed in electrical aspects such as ampere-turns and amps per square inch, optimizing electrical efficiency, voltage regulation, and insulation, there is a potential oversight regarding the intricate mechanical challenges associated with electrical design. As transformers evolve in [...] Read more.
While power transformer manufacturers are well versed in electrical aspects such as ampere-turns and amps per square inch, optimizing electrical efficiency, voltage regulation, and insulation, there is a potential oversight regarding the intricate mechanical challenges associated with electrical design. As transformers evolve in size and capacity, mechanical forces become increasingly significant, necessitating a closer examination of the mechanical aspects of electrical design. This study focuses on the design of power transformer tank walls. To address the challenge associated with larger tank wall deflection (for both the high-voltage and low-voltage sides) during pressure tests, different stiffeners such as flat stiffeners, changed flat stiffener dimensions, flat bar supports for stiffeners, and H-beams were added to the tank wall and modeled for finite element analysis. The tank wall design was optimized for higher mechanical strength, lower deflection, and lower mass by assessing the von Mises stress and deformation of different stiffeners. The findings of this study will contribute to a better understanding of how design adjustments affects mechanical strength, stress distribution, and overall reliability, providing valuable insights for the industry. Full article
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22 pages, 4098 KiB  
Article
Pharmacoinformatics, Molecular Dynamics Simulation, and Quantum Mechanics Calculation Based Phytochemical Screening of Croton bonplandianum Against Breast Cancer by Targeting Estrogen Receptor-α (ERα)
by Shuvo Saha, Partha Biswas, Mohaimenul Islam Tareq, Musfiqur Rahman Sakib, Suraia Akter Rakhi, Md. Nazmul Hasan Zilani, Abdel Halim Harrath, Md. Ataur Rahman and Md. Nazmul Hasan
Appl. Sci. 2024, 14(21), 9878; https://doi.org/10.3390/app14219878 - 29 Oct 2024
Viewed by 743
Abstract
Breast cancer progression is strongly influenced by estrogen receptor-α (ERα), a ligand-activated transcription factor that regulates hormone binding, DNA interaction, and transcriptional activation. ERα plays a key role in promoting cell proliferation in breast tissue, and its overexpression is associated with the advancement [...] Read more.
Breast cancer progression is strongly influenced by estrogen receptor-α (ERα), a ligand-activated transcription factor that regulates hormone binding, DNA interaction, and transcriptional activation. ERα plays a key role in promoting cell proliferation in breast tissue, and its overexpression is associated with the advancement of breast cancer through estrogen-mediated signaling pathways. Targeting ERα is, therefore, a promising therapeutic strategy for breast cancer. However, there are currently no phytochemical-based drug candidates approved for effectively inhibiting breast cancer progression driven by elevated ERα expression. This study aims to identify phytochemical inhibitors from Croton bonplandianum against ERα using pharmacoinformatics approaches. Eighty-three bioactive compounds from C. bonplandianum were retrieved from the IMPPAT (Indian Medicinal Plants, Phytochemistry, and Therapeutics) database and screened through molecular docking for their binding affinity to ERα. The top candidates were further evaluated through molecular dynamics simulations, ADME analysis, toxicity assessment, and quantum mechanics-based DFT calculations. The thermodynamic properties and HOMO-LUMO energy gap values indicated that the selected compounds were both stable and active. Among them, 2,3-oxidosqualene (CID-5366020) and 5,8,11-eicosatriynoic acid, trimethylsilyl ester (CID-91696396) demonstrated the most potent inhibitory activity against ERα. These findings suggest that these compounds have significant potential as therapeutic agents for breast cancer treatment by targeting ERα. Full article
(This article belongs to the Special Issue Bioinformatics & Computational Biology)
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13 pages, 2524 KiB  
Article
Combined Application of Biochar and Calcium Superphosphate Can Effectively Immobilize Cadmium and Reduce Its Uptake by Cabbage
by Xinlei Peng, Md. Shoffikul Islam, Qian Li, Qingling Fu, Jun Zhu and Hongqing Hu
Agronomy 2024, 14(11), 2538; https://doi.org/10.3390/agronomy14112538 - 28 Oct 2024
Viewed by 545
Abstract
Biochar and phosphate fertilizer are commonly employed for the mitigation of soil cadmium (Cd) contamination. Nevertheless, there is a dearth of research regarding the mechanism behind their joint implementation. In this study, a combination of corn straw biochar (0 (C0), 5 [...] Read more.
Biochar and phosphate fertilizer are commonly employed for the mitigation of soil cadmium (Cd) contamination. Nevertheless, there is a dearth of research regarding the mechanism behind their joint implementation. In this study, a combination of corn straw biochar (0 (C0), 5 (C5), and 10 (C10) g kg−1) and calcium superphosphate (0 (P0), 0.1 (P1), 0.2 (P2), 0.5 (P5), and 1.0 (P10) g kg−1) was applied in pot experiments, and the effects of the combined application on Cd bioavailability and its uptake by cabbage were investigated in Cd-contaminated soils. The results demonstrated that the combined treatment of applying biochar and Ca(H2PO2)2 yielded a significant decrease in the uptake of Cd by cabbage in alkaline soil, in contrast to the individual treatments of biochar or Ca(H2PO2)2. Compared to the CK treatment (C0P0), the Cd content in the shoots decreased by 46.26% and in the roots decreased by 24.81%, while the biomass of the cabbage demonstrated a noteworthy increase in C5P10 treatment. Compared to the CK treatment, the content of available phosphate (AP) in the soil increased by 17.57 mg kg−1, residual Cd increased by 22.02%, the exchangeable Cd decreased by 45.86%, and carbonate-bound Cd decreased by 20.55% in the C5P10 treatment. Therefore, it is advisable to use a combination of 5 g kg−1 biochar and 1 g kg−1 Ca(H2PO2)2 for the restoration of soil contaminated with Cd. Full article
(This article belongs to the Section Horticultural and Floricultural Crops)
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27 pages, 1230 KiB  
Article
Proof of Work with Random Selection (PoWR): An Energy Saving Consensus Algorithm with Proof of Work and the Random Selection Function
by Jin Woo Jung, Md. Mainul Islam and Hoh Peter In
Sustainability 2024, 16(21), 9342; https://doi.org/10.3390/su16219342 - 28 Oct 2024
Viewed by 827
Abstract
Bitcoin, which has been used for 13 years, has a role in transactions and investments as a major cryptocurrency. However, as the number of users increases, Bitcoin faces difficulties, such as scalability for transaction throughput and energy-consumption problems due to the concentration of [...] Read more.
Bitcoin, which has been used for 13 years, has a role in transactions and investments as a major cryptocurrency. However, as the number of users increases, Bitcoin faces difficulties, such as scalability for transaction throughput and energy-consumption problems due to the concentration of the mining pool. When Bitcoin first started to come out, it began to develop gradually through the mining of individuals. Nevertheless, as the price of the cryptocurrency gradually climbed, large mining corporation groups entered the mining competition with integrated circuit (IC) chips. Consequently, the substantial increase in power consumption is raising concerns regarding energy expenditure. This paper confirms that the verifiable random selection consensus protocol based on proof of work facilitates a fair and efficient system, enabling the participation of numerous individual miners in the mining competition while counteracting the monopolization of the hash rate by large mining corporations, thereby preserving the decentralization of mining. The protocol demonstrates the potential to mitigate substantial energy consumption. Moreover, it embodies features that create barriers to the adoption of high-energy-consuming application-specific integrated circuit equipment, significantly diminishing the principal factors contributing to extensive power utilization. Full article
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8 pages, 2815 KiB  
Proceeding Paper
Sustainable Bicycle Crank Arm Selection Using Life Cycle Analysis Under Typical Cycling Pedal Forces
by Arafater Rahman, Mohammad Abdul Wadud, Mohammad Abdul Hasib and Mohammad Ashraful Islam
Eng. Proc. 2024, 76(1), 43; https://doi.org/10.3390/engproc2024076043 - 28 Oct 2024
Viewed by 467
Abstract
This research compares the performance of structural steel and general aluminum alloys in identical crank arm designs when bearing loads are applied at different stages of paddling, such as starting, climbing, and racing. Finite element analysis (FEA) was utilized to evaluate fatigue life [...] Read more.
This research compares the performance of structural steel and general aluminum alloys in identical crank arm designs when bearing loads are applied at different stages of paddling, such as starting, climbing, and racing. Finite element analysis (FEA) was utilized to evaluate fatigue life and safety factors. A design modification strategy was proposed to reduce critical stress in failure zones, resulting in an increased fatigue life. Although steel and aluminum alloys both have significant life and nominal high fatigue life during racing and climbing, respectively, aluminum alloys are unable to withstand a 1815 N starting load, even after modification. Full article
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19 pages, 5580 KiB  
Article
A Comparative Effect of Sustainable Materials on the Immobilization, Geochemical Fractions, Bioaccumulation, and Translocation of Ni in Smelter- and Mine-Polluted Soils
by Altaf Hussain Lahori, Samreen Riaz Ahmed, Ambreen Afzal, Monika Mierzwa-Herstek, Aqsa Umar, Maria Taj Muhammad, Viola Vambol, Irfan Saleem, Abrar Ahmad Tanoli and Sergij Vambol
Minerals 2024, 14(11), 1083; https://doi.org/10.3390/min14111083 - 28 Oct 2024
Viewed by 593
Abstract
The present study holds significant implications, as it aims to investigate the comparative effect of biochar, zeolite, and bentonite minerals on the stabilization of Ni fractions, bioaccumulation, translocation indices, and the reduction in their absorption by pakchoi in smelter- and mine-contaminated soils. The [...] Read more.
The present study holds significant implications, as it aims to investigate the comparative effect of biochar, zeolite, and bentonite minerals on the stabilization of Ni fractions, bioaccumulation, translocation indices, and the reduction in their absorption by pakchoi in smelter- and mine-contaminated soils. The results, which are of great interest, showed that the maximum fresh and dry biomasses of pakchoi were observed up to 28.21 and 18.43% for smelter-polluted soil and 61.96 and 67.90% for mine-contaminated soil amended with zeolite compared to the control. Applying zeolite increased pakchoi chlorophyll SPAD values 1.17-fold in smelter soil and 1.26-fold in mine-polluted soil. The highest Ni immobilization in smelter and mine soil was observed at 76.8 and 85.38% with the application of bentonite, which increased soil pH and CEC. The application of biochar, bentonite, and zeolite reduced the Ni residual, oxidizable, and acid-soluble fractions, but biochar and bentonite increased the reducible fraction of Ni in smelter soil. The highest reduction in Ni in the shoot and root was noted as 82.08 and 68.28% of smelter-polluted soil and 77.25 and 89.61% of mine-polluted soil with bentonite compared to control soil. Overall, it has been concluded that biochar, zeolite, and bentonite can be successfully used to mitigate the Ni concentration in smelter- and mine-polluted soil and reduce uptake by vegetable crops. Full article
(This article belongs to the Special Issue Geochemical Characteristics and Contamination Risk Assessment of Soil)
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21 pages, 1089 KiB  
Article
Cloud IaaS Optimization Using Machine Vision at the IoT Edge and the Grid Sensing Algorithm
by Nuruzzaman Faruqui, Sandesh Achar, Sandeepkumar Racherla, Vineet Dhanawat, Prathyusha Sripathi, Md. Monirul Islam, Jia Uddin, Manal A. Othman, Md Abdus Samad and Kwonhue Choi
Sensors 2024, 24(21), 6895; https://doi.org/10.3390/s24216895 - 27 Oct 2024
Viewed by 987
Abstract
Security grids consisting of High-Definition (HD) Internet of Things (IoT) cameras are gaining popularity for organizational perimeter surveillance and security monitoring. Transmitting HD video data to cloud infrastructure requires high bandwidth and more storage space than text, audio, and image data. It becomes [...] Read more.
Security grids consisting of High-Definition (HD) Internet of Things (IoT) cameras are gaining popularity for organizational perimeter surveillance and security monitoring. Transmitting HD video data to cloud infrastructure requires high bandwidth and more storage space than text, audio, and image data. It becomes more challenging for large-scale organizations with massive security grids to minimize cloud network bandwidth and storage costs. This paper presents an application of Machine Vision at the IoT Edge (Mez) technology in association with a novel Grid Sensing (GRS) algorithm to optimize cloud Infrastructure as a Service (IaaS) resource allocation, leading to cost minimization. Experimental results demonstrated a 31.29% reduction in bandwidth and a 22.43% reduction in storage requirements. The Mez technology offers a network latency feedback module with knobs for transforming video frames to adjust to the latency sensitivity. The association of the GRS algorithm introduces its compatibility in the IoT camera-driven security grid by automatically ranking the existing bandwidth requirements by different IoT nodes. As a result, the proposed system minimizes the entire grid’s throughput, contributing to significant cloud resource optimization. Full article
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12 pages, 270 KiB  
Article
The Test of Sports and Folk Narratives with the Notion of Haram: Citing the Example of the Branch of Wrestling
by Ünsal Yılmaz Yeşildal, Doğukan Batur Alp Gülşen and Cihat Burak Korkmaz
Religions 2024, 15(11), 1311; https://doi.org/10.3390/rel15111311 - 26 Oct 2024
Viewed by 728
Abstract
Culture consists of material and spiritual values and tools that a nation has accumulated in the historical process. In addition to the most basic contexts such as language and religion, contexts such as sporting activities, art, public medicine, and the public calendar are [...] Read more.
Culture consists of material and spiritual values and tools that a nation has accumulated in the historical process. In addition to the most basic contexts such as language and religion, contexts such as sporting activities, art, public medicine, and the public calendar are also important environments that reveal their own cultural elements. Among these contexts, religion is very effective in shaping the daily life of the individual and, thus, society through the rules it enjoins. Religion does not dominate only the world of belief of the individual. Through the world of belief, it also directs their relations with the social institutions they are involved in. Sport is one of the most important activities and social institutions that stand out with various functions in daily life, with wrestling being one of the branches of sports that have emerged as a result of the imitation of the struggle of human beings with nature and other creatures with which they share nature. In particular, those involved in the nomadic way of life had to hunt in order not to starve and fight in order to survive. Wrestling, which emerged as a result of these obligations, held an important place among all Turks in the world for a period of time, especially in the transition periods of life, such as birth, marriage, and death. One of the conditions set forth by women as a condition of marriage was that their suitor defeated them in wrestling. Examples of this condition are also observed in literary texts belonging to different periods when Turks were not yet acquainted with Islam and the concepts of halal and haram, which entered their lives together with Islam. According to the provisions of the Holy Qur’an, right/unprohibited thoughts and actions are associated with the words good and halal, while wrong/prohibited thoughts and actions are associated with the words sin and haram. In this study, the social and cultural phases of wrestling as a sports branch among Turks in the historical process will be evaluated on the basis of the history of religions and religious references, in addition to the literary texts belonging to historical periods when Turks were members of different religions, in the context of two events that have been experienced and reported in the news. The study was carried out using the method of document analysis, a method of qualitative research, and the data obtained by this method were evaluated using content analysis. The narratives of Alıp Manaş, Alpamış, Alpamıs, Alıpmenşen, and Bamsı Beyrek, which are evaluated in this context, belong to the periods when the Turks had not been introduced to Islam or had only recently been introduced to it. Alıp Manaş was collated from different Turkic tribes such as the Altais, Alpamış from the Uzbeks, Alpamıs the Kazakhs/Karakalpaks, Alıpmenşen the Bashkirs/Tatars, and Bamsı Beyrek the Oghuz Turks. The narratives of Kirmanshah, Köse Kenan-Dânâ Hanım, Bey Böyrek, Shah Ismail, and Yaralı Mahmut, which are evaluated in the study, belong to the periods when the Turks became Muslim en masse, and are related only among the Oghuz Turks. These narratives are included in the study because they are similar to Alıp Manaş, Alpamış, Alpamıs, Alıpmenşen, and Bamsı Beyrek and they belong to the period when Islam was largely established among the Turkish masses in Anatolia. The effect of the new religion on wrestling, which is a branch of sport, will be revealed through these narratives belonging to different tribes and religious periods. Once more, an event that occurred in recent history, and was the subject of the news, was subjected to document analysis, and content analysis was carried out through the text of the news and evaluated in the context of the study. This study aims to explain the effect of religious rules on sports branches with theological, folkloric, and sociological references based on ancient literary texts belonging to the Turks and two incidents which were experienced. Full article
(This article belongs to the Special Issue Sport and Religion: Continuities, Connections, Concerns)
50 pages, 8165 KiB  
Review
Empowering Fuel Cell Electric Vehicles Towards Sustainable Transportation: An Analytical Assessment, Emerging Energy Management, Key Issues, and Future Research Opportunities
by Tuhibur Rahman, Md. Sazal Miah, Tahia F. Karim, Molla Shahadat Hossain Lipu, Abu M. Fuad, Zia Ul Islam, M. M. Naushad Ali, Mohammed Nazmus Shakib, Shafrida Sahrani and Mahidur R. Sarker
World Electr. Veh. J. 2024, 15(11), 484; https://doi.org/10.3390/wevj15110484 - 26 Oct 2024
Viewed by 1873
Abstract
Fuel cell electric vehicles (FCEVs) have received significant attention in recent times due to various advantageous features, such as high energy efficiency, zero emissions, and extended driving range. However, FCEVs have some drawbacks, including high production costs; limited hydrogen refueling infrastructure; and the [...] Read more.
Fuel cell electric vehicles (FCEVs) have received significant attention in recent times due to various advantageous features, such as high energy efficiency, zero emissions, and extended driving range. However, FCEVs have some drawbacks, including high production costs; limited hydrogen refueling infrastructure; and the complexity of converters, controllers, and method execution. To address these challenges, smart energy management involving appropriate converters, controllers, intelligent algorithms, and optimizations is essential for enhancing the effectiveness of FCEVs towards sustainable transportation. Therefore, this paper presents emerging energy management strategies for FCEVs to improve energy efficiency, system reliability, and overall performance. In this context, a comprehensive analytical assessment is conducted to examine several factors, including research trends, types of publications, citation analysis, keyword occurrences, collaborations, influential authors, and the countries conducting research in this area. Moreover, emerging energy management schemes are investigated, with a focus on intelligent algorithms, optimization techniques, and control strategies, highlighting contributions, key findings, issues, and research gaps. Furthermore, the state-of-the-art research domains of FCEVs are thoroughly discussed in order to explore various research domains, relevant outcomes, and existing challenges. Additionally, this paper addresses open issues and challenges and offers valuable future research opportunities for advancing FCEVs, emphasizing the importance of suitable algorithms, controllers, and optimization techniques to enhance their performance. The outcomes and key findings of this review will be helpful for researchers and automotive engineers in developing advanced methods, control schemes, and optimization strategies for FCEVs towards greener transportation. Full article
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19 pages, 4587 KiB  
Article
Sustainable Activated Carbon from Agricultural Waste: A Study on Adsorption Efficiency for Humic Acid and Methyl Orange Dyes
by Zahia Tigrine, Ouassila Benhabiles, Leila Merabti, Nadia Chekir, Mounir Mellal, Salaheddine Aoudj, Nora Amele Abdeslam, Djilali Tassalit, Seif El Islam Lebouachera and Nadjib Drouiche
Sustainability 2024, 16(21), 9308; https://doi.org/10.3390/su16219308 - 26 Oct 2024
Viewed by 1004
Abstract
In this study, porous activated carbon was produced from coffee waste and used as an effective adsorbent for the removal of humic acid (HA) from seawater and methyl orange (MO) dye from aqueous solutions. Phosphoric acid H3PO4 was used as [...] Read more.
In this study, porous activated carbon was produced from coffee waste and used as an effective adsorbent for the removal of humic acid (HA) from seawater and methyl orange (MO) dye from aqueous solutions. Phosphoric acid H3PO4 was used as an activating agent for the chemical activation of these agricultural wastes. The characterization of the activated carbon obtained using a scanning electron microscope (SEM), Fourier-transform infrared (FTIR) spectroscopy analysis, X-ray diffraction (XRD) and the Brunauer–Emmett–Teller (BET) method revealed that the activated carbon products exhibited high porosity and the formation of various functional groups. The effects of different parameters were examined using batch adsorption experiments, such as the adsorbent masses, pH, initial pollutant concentration and contact time. The results show that the performance increased with an increased adsorbent mass (up to 0.25 g/L) and decreased initial concentration of the adsorbent tested. On the other hand, this study clearly showed that the adsorption efficiency of the MO on the raw spent coffee grounds (SCGs) waste was around 43%, while no removal was observed for the humic acid. The experiments demonstrated that the activated carbon synthesized from the used coffee grounds (the efficiency was compared with commercial activated carbon (CAC) with a difference of 13%) was a promising alternative to commercially available adsorbents for the removal of humic acid from seawater. To understand and elucidate the adsorption mechanism, various isothermal and kinetic models were studied. The adsorption capacity was analyzed by fitting experimental data to these models. The experimental data for methyl orange dyes were analyzed using Langmuir and Freundlich isothermal models. The Freundlich isotherm model provided a superior fit to the equilibrium data, as indicated by a higher correlation coefficient (R2) than that of the Langmuir model. The maximum adsorption was observed at pH 3. The Freundlich adsorption capacity was found to be 333 mg/g adsorbent. The PAC showed a high adsorption capacity for the MO and HA. The PAC showed the highest adsorption capacities for the HA and MO compared with the other adsorbents used (SCGs and CAC) and would be a good material to increase the adsorption efficiency for humic acid removal in the seawater pretreatment process. In addition, the prepared AC BET surface area was 520.40 m2/g, suggesting a high adsorption capacity. This makes the material potentially suitable for various applications that require a high surface area. These results indicate that high-quality sustainable activated carbon can be efficiently produced from coffee waste, making it suitable for a wide range of adsorbent applications targeting various pollutants. Full article
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21 pages, 11679 KiB  
Article
Adjustment of Mechanical Properties of 3D Printed Continuous Carbon Fiber-Reinforced Thermoset Composites by Print Parameter Adjustments
by Md Atikur Rahman, Luke Gibbon, Md Zahirul Islam, Eric Hall and Chad A. Ulven
Polymers 2024, 16(21), 2996; https://doi.org/10.3390/polym16212996 - 25 Oct 2024
Viewed by 605
Abstract
Reinforcing thermoset polymers with continuous carbon fiber (CF) tow has emerged as a promising avenue to overcome the thermal and mechanical performance limitations of 3D printed polymeric structures for load-bearing applications. Unlike traditional methods, manufacturing continuous fiber-reinforced composites by 3D printing has the [...] Read more.
Reinforcing thermoset polymers with continuous carbon fiber (CF) tow has emerged as a promising avenue to overcome the thermal and mechanical performance limitations of 3D printed polymeric structures for load-bearing applications. Unlike traditional methods, manufacturing continuous fiber-reinforced composites by 3D printing has the unique capability of locally varying the mechanical properties of the composites. In this study, continuous CF thermoset composite specimens were printed with varying line spacing, resin flow rate, and nozzle sizes. The resin flow rates for different line spacings and nozzle sizes were optimized by topographic analysis. Printed composite mechanical properties were evaluated, and their trends were correlated with the trend of print parameter changes. Results showed that tensile strength and modulus could be altered and improved by ~50% by adjusting the printing process parameters. Higher composite strength and modulus were obtained by shortening the line spacing and nozzle diameter. Full article
(This article belongs to the Special Issue Research on Additive Manufacturing of Polymer Composites)
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15 pages, 571 KiB  
Article
Prevalence and Factors of Pregnancy Termination Among Reproductive-Aged Women: Evidence from the Bangladesh Demographic and Health Survey
by Md. Rabiul Islam, Makfiratur Rahman, Arifa Farzana Tanha, Nusrat Hossain Sheba, S. M. Raysul Haque, Md. Kamran ul Baset, Zenat Zebin Hossain, Mohammad Abbas Gani and J. M. A. Hannan
Healthcare 2024, 12(21), 2130; https://doi.org/10.3390/healthcare12212130 - 25 Oct 2024
Viewed by 1124
Abstract
Background: Pregnancy termination (PT) is a major public health concern in low-and middle-income countries like Bangladesh. This cross-sectional study aimed to determine the prevalence and factors of PT using the nationally representative Bangladesh Demographic and Health Survey data 2017–2018. Materials and Methods: A [...] Read more.
Background: Pregnancy termination (PT) is a major public health concern in low-and middle-income countries like Bangladesh. This cross-sectional study aimed to determine the prevalence and factors of PT using the nationally representative Bangladesh Demographic and Health Survey data 2017–2018. Materials and Methods: A weighted population-based sample of 8759 ever-married reproductive-aged women (15–49 years) was included in the study. The outcome variable was PT in any of the following forms: miscarriage, induced abortion, and stillbirth. A univariate analysis for mean, frequency, and percentage and multiple logistical regression were used to determine the factors associated with PT. Results: Around 18% of the women were found to have PT. The mean age of the women in the study was 25.79 years; 65.1% lived in the rural areas, and the majority of them were Muslims. Advanced age of the women (AOR:3.49, p = 0.004), residence in the countryside (AOR:0.81, p = 0.002), higher education (AOR:0.72, p = 0.027), not being a Muslim (AOR:0.74, p = 0.010), higher socio-economic status (AOR:1.28, p = 0.027), having a job (AOR:1.15, p = 0.041), being married at the age of >22 years (AOR:0.71, p = 0.036), and using a mobile phone (AOR:1.22, p = 0.002) were significant factors of PT. This study did not find any association between PT and contraceptive use. Conclusions: Age, living region, education, religion, wealth index, working status, marital age, and mobile phone use are the determinants of PT. Interventions including these factors need to be made to reduce PT in Bangladeshi women. These findings could be helpful in undertaking further epidemiological studies to understand the actual causes of PT in various rural and urban settings among different socio-demographic groups in Bangladesh. Full article
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25 pages, 6325 KiB  
Article
An In Silico Approach to Discover Efficient Natural Inhibitors to Tie Up Epstein–Barr Virus Infection
by Ayan Das, Mumtaza Mumu, Tanjilur Rahman, Md Abu Sayeed, Md Mazharul Islam, John I. Alawneh and Mohammad Mahmudul Hassan
Pathogens 2024, 13(11), 928; https://doi.org/10.3390/pathogens13110928 - 25 Oct 2024
Viewed by 1315
Abstract
Epstein–Barr virus (EBV), also known as human herpesvirus 4, is a member of the herpes virus family. EBV is a widespread virus and causes infectious mononucleosis, which manifests with symptoms such as fever, fatigue, lymphadenopathy, splenomegaly, and hepatomegaly. Additionally, EBV is associated with [...] Read more.
Epstein–Barr virus (EBV), also known as human herpesvirus 4, is a member of the herpes virus family. EBV is a widespread virus and causes infectious mononucleosis, which manifests with symptoms such as fever, fatigue, lymphadenopathy, splenomegaly, and hepatomegaly. Additionally, EBV is associated with different lymphocyte-associated non-malignant, premalignant, and malignant diseases. So far, no effective treatment or therapeutic drug is known for EBV-induced infections and diseases. This study investigated natural compounds that inhibit EBV glycoprotein L (gL) and block EBV fusion in host cells. We utilised computational approaches, including molecular docking, in silico ADMET analysis, and molecular dynamics simulation. We docked 628 natural compounds against gL and identified the four best compounds based on binding scores and pharmacokinetic properties. These four compounds, with PubChem CIDs 4835509 (CHx-HHPD-Ac), 2870247 (Cyh-GlcNAc), 21206004 (Hep-HHPD-Ac), and 51066638 (Und-GlcNAc), showed several interactions with EBV gL. However, molecular dynamics simulations indicated that the protein–ligand complexes of CID: 4835509 (CHx-HHPD-Ac) and CID: 2870247 (Cyh-GlcNAc) are more stable than those of the other two compounds. Therefore, CIDs 4835509 and 2870247 (Cyh-GlcNAc) may be potent natural inhibitors of EBV infection. These findings can open a new way for effective drug design against EBV and its associated infections and diseases. Full article
(This article belongs to the Section Viral Pathogens)
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18 pages, 317 KiB  
Entry
Loyalty in Islam: A Critical Survey
by Abdessamad Belhaj
Encyclopedia 2024, 4(4), 1599-1616; https://doi.org/10.3390/encyclopedia4040105 - 25 Oct 2024
Viewed by 1120
Definition
Up until recently, research on loyalty and Islam—here considered as the discourses and practices of Muslims in regard to the Muslim tradition—had ignored the topic of loyalty. Interest in loyalty in Islam has just lately grown sufficiently and extensively. This entry is both [...] Read more.
Up until recently, research on loyalty and Islam—here considered as the discourses and practices of Muslims in regard to the Muslim tradition—had ignored the topic of loyalty. Interest in loyalty in Islam has just lately grown sufficiently and extensively. This entry is both bibliographical and thematic. It seeks to identify the principal themes that have dominated Muslim loyalty studies for the past thirty years or so. Additionally, it provides a thorough synopsis of over 100 studies on loyalty that were published during the same time span in Arabic and European languages. Allegiance in Muslim political ethics always had more than one connotation and the religious component of loyalty, while not strictly defined, allowed and even justified the overlap of multiple loyalties. A person’s or a family’s, ruler’s, or dynasty’s power to govern an area or defend religious institutions and symbols was intimately linked to the loyalty they could claim. Most studies agree on the diversity of political allegiance in modern Islam with regard to perceptions of religion, ethnicity, self-interest, etc.; it is also co-relative in the sense that it is mixed with other allegiances, such as those of family, tribe, leadership, or country. Full article
(This article belongs to the Section Arts & Humanities)
18 pages, 5666 KiB  
Article
The Investigation of Nonlinear Time-Fractional Models in Optical Fibers and the Impact Analysis of Fractional-Order Derivatives on Solitary Waves
by Muhammad Idrees Afridi, Tamanna Islam, Md Ali Akbar and Mohamed S. Osman
Fractal Fract. 2024, 8(11), 627; https://doi.org/10.3390/fractalfract8110627 - 24 Oct 2024
Cited by 1 | Viewed by 795
Abstract
In this article, we investigate a couple of nonlinear time-fractional evolution equations, namely the cubic-quintic-septic-nonic equation and the Davey–Stewartson (DS) equation, both of which have significant applications in complex physical phenomena such as fiber optical communication, optical signal processing, and nonlinear optics. Using [...] Read more.
In this article, we investigate a couple of nonlinear time-fractional evolution equations, namely the cubic-quintic-septic-nonic equation and the Davey–Stewartson (DS) equation, both of which have significant applications in complex physical phenomena such as fiber optical communication, optical signal processing, and nonlinear optics. Using a powerful technique named the extended generalized Kudryashov approach, we extract different rich structured soliton solutions to these models, including bell-shaped, cuspon, parabolic soliton, singular soliton, and squeezed bell-shaped soliton. We also study the impact of fractional-order derivatives on these solutions, providing new insights into the dynamics of nonlinear models. The results are compared with the existing literature, revealing novel and distinct solutions that offer a deeper understanding of these fractional models. The results show that the implemented approach is useful, reliable, and compatible for examining fractional nonlinear evolution equations in applied science and engineering. Full article
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