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COMT catechol-O-methyltransferase [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 712548, updated on 17-Aug-2024

Summary

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Official Symbol
COMTprovided by VGNC
Official Full Name
catechol-O-methyltransferaseprovided by VGNC
Primary source
VGNC:VGNC:107781
See related
Ensembl:ENSMMUG00000054068
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See COMT in Genome Data Viewer
Location:
chromosome: 10
Exon count:
9
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 10 NC_041763.1 (32673713..32702017, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 10 NC_027902.1 (61669742..61699553)

Chromosome 10 - NC_041763.1Genomic Context describing neighboring genes Neighboring gene tRNA methyltransferase 2 homolog A Neighboring gene DGCR8 microprocessor complex subunit Neighboring gene transport and golgi organization 2 homolog Neighboring gene microRNA mir-185 Neighboring gene ARVCF delta catenin family member Neighboring gene thioredoxin reductase 2 Neighboring gene G protein subunit beta 1 like Neighboring gene retrotransposon Gag like 10 Neighboring gene T-box transcription factor 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables catechol O-methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in catecholamine catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in developmental process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in dopamine metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in dendrite IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
catechol O-methyltransferase
NP_001247941.1
XP_015005207.2
XP_015005208.2
XP_015005209.2
XP_015005210.2
XP_015005211.2
XP_028683178.1
XP_028683179.1
XP_028683180.1
XP_028683181.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001261012.2 → NP_001247941.1  catechol O-methyltransferase

    See identical proteins and their annotated locations for NP_001247941.1

    Status: PROVISIONAL

    Source sequence(s)
    JV046207
    UniProtKB/TrEMBL
    F6QFW9, I2CT60
    Related
    ENSMMUP00000074706.1, ENSMMUT00000101642.1
    Conserved Domains (1) summary
    cl17173
    Location:66 → 227
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041763.1 Reference Mmul_10 Primary Assembly

    Range
    32673713..32702017 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015149725.2 → XP_015005211.2  catechol O-methyltransferase isoform X1

    UniProtKB/TrEMBL
    A0A5F8A4J5, I2CT60
    Conserved Domains (1) summary
    COG4122
    Location:95 → 263
    YrrM; Predicted O-methyltransferase YrrM [General function prediction only]

  2. XM_015149723.2 → XP_015005209.2  catechol O-methyltransferase isoform X1

    UniProtKB/TrEMBL
    A0A5F8A4J5, I2CT60
    Conserved Domains (1) summary
    COG4122
    Location:95 → 263
    YrrM; Predicted O-methyltransferase YrrM [General function prediction only]

  3. XM_015149721.2 → XP_015005207.2  catechol O-methyltransferase isoform X1

    UniProtKB/TrEMBL
    A0A5F8A4J5, I2CT60
    Related
    ENSMMUP00000078293.1, ENSMMUT00000088651.1
    Conserved Domains (1) summary
    COG4122
    Location:95 → 263
    YrrM; Predicted O-methyltransferase YrrM [General function prediction only]

  4. XM_028827348.1 → XP_028683181.1  catechol O-methyltransferase isoform X1

    UniProtKB/TrEMBL
    A0A5F8A4J5, I2CT60
    Related
    ENSMMUP00000067362.1, ENSMMUT00000091430.1
    Conserved Domains (1) summary
    COG4122
    Location:95 → 263
    YrrM; Predicted O-methyltransferase YrrM [General function prediction only]

  5. XM_015149724.2 → XP_015005210.2  catechol O-methyltransferase isoform X1

    UniProtKB/TrEMBL
    A0A5F8A4J5, I2CT60
    Related
    ENSMMUP00000074558.1, ENSMMUT00000101370.1
    Conserved Domains (1) summary
    COG4122
    Location:95 → 263
    YrrM; Predicted O-methyltransferase YrrM [General function prediction only]

  6. XM_015149722.2 → XP_015005208.2  catechol O-methyltransferase isoform X1

    UniProtKB/TrEMBL
    A0A5F8A4J5, I2CT60
    Conserved Domains (1) summary
    COG4122
    Location:95 → 263
    YrrM; Predicted O-methyltransferase YrrM [General function prediction only]

  7. XM_028827345.1 → XP_028683178.1  catechol O-methyltransferase isoform X1

    UniProtKB/TrEMBL
    A0A5F8A4J5, I2CT60
    Related
    ENSMMUP00000066668.1, ENSMMUT00000102660.1
    Conserved Domains (1) summary
    COG4122
    Location:95 → 263
    YrrM; Predicted O-methyltransferase YrrM [General function prediction only]

  8. XM_028827346.1 → XP_028683179.1  catechol O-methyltransferase isoform X1

    UniProtKB/TrEMBL
    A0A5F8A4J5, I2CT60
    Related
    ENSMMUP00000080728.1, ENSMMUT00000103331.1
    Conserved Domains (1) summary
    COG4122
    Location:95 → 263
    YrrM; Predicted O-methyltransferase YrrM [General function prediction only]

  9. XM_028827347.1 → XP_028683180.1  catechol O-methyltransferase isoform X1

    UniProtKB/TrEMBL
    A0A5F8A4J5, I2CT60
    Conserved Domains (1) summary
    COG4122
    Location:95 → 263
    YrrM; Predicted O-methyltransferase YrrM [General function prediction only]
Nucleotide Protein
Heading Accession and Version

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