RecName: Full=Multifunctional protein CAD; AltName: Full=Carbamoyl pho - Protein

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Highlight Sequence Features
Opens the Highlight Feature Bar and highlights feature annotations from the FEATURES table of the record. The Highlight Feature Bar can be used to navigate to and highlight other features and provides links to display the highlighted region separately. Links in the FEATURES table will also highlight the corresponding region of the sequence. More...
Find in this Sequence
Finds sub-sequences or patterns in the sequence and highlights the matching regions. The tool works with standard single letter nucleotide or protein codes including ambiguities and can match Prosite patterns in protein sequences. More...

Beyond genetics: Deciphering the impact of missense variants in CAD deficiency. [J Inherit Metab Dis. 2023]
Beyond genetics: Deciphering the impact of missense variants in CAD deficiency.
Del Caño-Ochoa F, Ng BG, Rubio-Del-Campo A, Mahajan S, Wilson MP, Vilar M, Rymen D, Sánchez-Pintos P, Kenny J, Ley Martos M, et al. J Inherit Metab Dis. 2023 Nov; 46(6):1170-1185. Epub 2023 Sep 11.
Deciphering CAD: Structure and function of a mega-enzymatic pyrimidine factory in health and disease. [Protein Sci. 2021]
Deciphering CAD: Structure and function of a mega-enzymatic pyrimidine factory in health and disease.
Del Caño-Ochoa F, Ramón-Maiques S. Protein Sci. 2021 Oct; 30(10):1995-2008. Epub 2021 Jul 22.
Uridine treatment normalizes the congenital dyserythropoietic anemia type II-like hematological phenotype in a patient with homozygous mutation in the CAD gene. [Am J Hematol. 2020]
Uridine treatment normalizes the congenital dyserythropoietic anemia type II-like hematological phenotype in a patient with homozygous mutation in the CAD gene.
Russo R, Marra R, Andolfo I, Manna F, De Rosa G, Rosato BE, Radhakrishnan K, Fahey M, Iolascon A. Am J Hematol. 2020 Nov; 95(11):1423-1426. Epub 2020 Aug 19.

RefSeq genomic sequence
See the genomic reference sequence for the CAD gene (NG_046394.1).
RefSeq protein isoforms
See 6 reference sequence protein isoforms for the CAD gene.

PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioAssay by Target (Summary)
BioAssay by Target (Summary)
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
Identical Structures
3D structures for identical protein sequences
OMIM
OMIM records associated with protein sequence
Protein (RefSeq)
Protein gi (UniProtKB) to protein gi (refseq)
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures

MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

RecName: Full=Multifunctional protein CAD; AltName: Full=Carbamoyl phosphate syn...
RecName: Full=Multifunctional protein CAD; AltName: Full=Carbamoyl phosphate synthetase 2-aspartate transcarbamylase-dihydroorotase; Includes: RecName: Full=Glutamine-dependent carbamoyl phosphate synthase; Includes: RecName: Full=Glutamine amidotransferase; Short=GATase; Short=GLNase; Includes: RecName: Full=Ammonium-dependent carbamoyl phosphate synthase; Short=CPS; Short=CPSase; Includes: RecName: Full=Aspartate carbamoyltransferase; Includes: RecName: Full=Dihydroorotase
gi|50403731|sp|P27708.3|PYR1_HUMAN

Protein

Your browsing activity is empty.

Activity recording is turned off.

Protein