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1/f neural noise and electrophysiological indices of contextual prediction in aging

Brain Res. 2018 Jul 15:1691:34-43. doi: 10.1016/j.brainres.2018.04.007. Epub 2018 Apr 18.

Abstract

Prediction of upcoming words during reading has been suggested to enhance the efficiency of discourse processing. Emerging models have postulated that predictive mechanisms require synchronous firing of neural networks, but to date, this relationship has been investigated primarily through oscillatory activity in narrow frequency bands. A recently-developed measure proposed to reflect broadband neural activity - and thereby synchronous neuronal firing - is 1/f neural noise extracted from EEG spectral power. Previous research has indicated that this measure of 1/f neural noise changes across the lifespan, and these neural changes predict age-related behavioral impairments in visual working memory. Using a cross-sectional sample of young and older adults, we examined age-related changes in 1/f neural noise and whether this measure predicted ERP correlates of successful lexical prediction during discourse comprehension. 1/f neural noise across two different language tasks revealed high within-subject correlations, indicating that this measure can provide a reliable index of individualized patterns of neural activation. In addition to age, 1/f noise was a significant predictor of N400 effects of successful lexical prediction; however, noise did not mediate age-related declines in other ERP effects. We discuss broader implications of these findings for theories of predictive processing, as well as potential applications of 1/f noise across research populations.

Keywords: Aging; Discourse processing; ERPs; Neural noise; Prediction.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aging / physiology*
  • Brain Mapping*
  • Comprehension / physiology*
  • Electroencephalography
  • Evoked Potentials / physiology*
  • Female
  • Fourier Analysis
  • Humans
  • Language
  • Male
  • Middle Aged
  • Models, Neurological*
  • Photic Stimulation
  • Predictive Value of Tests
  • Reading
  • Young Adult