Rituximab induced cytokine release syndrome in an MS patient: A case report

Masoud Etemadifar; Mehri Salari; Mahdieh Saeri; Amirhossein Akhavan Sigari; Sara Ebrahimi Pelarti

doi:10.1002/ccr3.4407

Rituximab induced cytokine release syndrome in an MS patient: A case report

Clin Case Rep. 2021 Jul 9;9(7):e04407. doi: 10.1002/ccr3.4407. eCollection 2021 Jul.

Authors

Masoud Etemadifar¹, Mehri Salari², Mahdieh Saeri³, Amirhossein Akhavan Sigari³, Sara Ebrahimi Pelarti³

Affiliations

¹ Department of Neurosurgery Alzahra University Hospital Isfahan University of Medical Sciences Isfahan Iran.
² Functional Neurosurgery Research Center Shohada Tajrish Comprehensive Neurosurgical Center of Excellence Shahid Beheshti University of Medical Sciences Tehran Iran.
³ Alzahra Research Institute Alzahra University Hospital Isfahan University of Medical Sciences Isfahan Iran.

Abstract

Cytokine release syndrome with rituximab has been reported in certain diseases, however, it is rarely reported in MS patients treated with rituximab. The treating physician should suspect the syndrome when typical signs and symptoms appear.

Keywords: cytokine release syndrome; multiple sclerosis; rituximab.

Publication types

Case Reports