Lab-On-a-Chip Technologies for Microgravity Simulation and Space Applications

Aditya Vashi; Kamalalayam Rajan Sreejith; Nam-Trung Nguyen

doi:10.20944/preprints202212.0139.v1

Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Version 1 : Received: 7 December 2022 / Approved: 8 December 2022 / Online: 8 December 2022 (01:59:14 CET)

Gravity played an important role in the development of life on earth. The effect of gravity on a living organisms can be investigated by controlling the magnitude of gravity. Most reduced gravity experiments are conducted on the lower earth orbit (LEO) in the International Space Station (ISS). However, running experiments in ISS face challenges such as high cost, extreme condition, lack of direct accessibility, and long waiting period. Therefore, researchers have developed various ground-based devices and methods to perform reduced gravity experiments. However, the search for life outside the earth requires more intensive research. Advancements in conventional methods and the development of new tools are required for this purpose. The advantages of Lab-on-a-Chip (LOC) devices make them an attractive option for simulating microgravity. This paper briefly reviews the advancement of LOC technologies for simulating microgravity in a earth-based laboratory.

Microgravity simulation; Lab-On-a-Chip (LOC); Space application; Clinostats; Rotating wall vessel (RWV); Random position machine (RPM); Diamagnetic levitation; CubeSat; Acoustic levitation; Levitation

Engineering, Mechanical Engineering

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Lab-On-a-Chip Technologies for Microgravity Simulation and Space Applications

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