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Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

MicroRNAs Role in Diagnosis and Treatment of Subarachnoid Hemorrhage

Version 1 : Received: 25 April 2023 / Approved: 26 April 2023 / Online: 26 April 2023 (12:44:56 CEST)

A peer-reviewed article of this Preprint also exists.

Segherlou, Z.H.; Saldarriaga, L.; Azizi, E.; Vo, K.-A.; Reddy, R.; Siyanaki, M.R.H.; Lucke-Wold, B. MicroRNAs’ Role in Diagnosis and Treatment of Subarachnoid Hemorrhage. Diseases 2023, 11, 77. Segherlou, Z.H.; Saldarriaga, L.; Azizi, E.; Vo, K.-A.; Reddy, R.; Siyanaki, M.R.H.; Lucke-Wold, B. MicroRNAs’ Role in Diagnosis and Treatment of Subarachnoid Hemorrhage. Diseases 2023, 11, 77.

Abstract

Subarachnoid hemorrhage (SAH) is most commonly seen in patients over 55 years of age and often results in a loss of many productive years. SAH has a high mortality rate, and sur-vivors often suffer from early and secondary brain injuries. Understanding the pathophysiology of the SAH is crucial to identifying potential therapeutic agents. One promising target for diagno-sis and prognosis of SAH is circulating microRNAs, which regulate gene expression and are in-volved in various physiological and pathological processes. In this review, we discuss the poten-tial of microRNAs as a target for diagnosis, treatment, and prognosis in SAH.

Keywords

Aneurysmal Subarachnoid Hemorrhage; microRNAs; Exosomes

Subject

Medicine and Pharmacology, Neuroscience and Neurology

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