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rel ease that will result in restoration of normal osmolality Example: Drink pure water pure ==> plasma ==> osmoreceptors ==> ADH ==> H2O drink osmolality discharge rate release ==> urine volume ==> plasma osmolality urine concentration (to normal) Example: Eat salt NaCl ==> plasma ==> osmoreceptor ==> ADH ==> ingest osmolality discharge rate release ==> urine volume ==> plasma osmolality urine concentration (to normal) Note: Similar homeostatic responses to dehydration (defense of fluid volume) or severe hypotension (defense of intravascular volume)