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Morphine Dose: - Morphine 5-10mg IV (Repeat After

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Morphine Dose

Morphine 510mg IV (repeat after


5min if necessary). Give anti-emetic
with the 1st dose of morphine:
metoclopramide 10mg IV (1st line), or
cyclizine 50mg IV (2nd line).

Oxford Handbook of Clinical Medicine

Morphine Dose
Morphine sulfate (2 to 4 mg
intravenously [IV] with increments of
2 to 8 mg IV at five- to 15-minute
intervals) is the analgesic of choice
for management of pain associated
with STEMI.

ACC/AHA

Unfractionated Heparin:
Bolus: 60 U/kg IV (not to exceed 4000 U)
Infusion: 12 U/kg/hr IV (not to exceed 1000U/hr) to
goal aPTT 1.5 to 2.0 times (~50-70 detik); check
PTT in 6 hours and adjust heparin as below.
(Continue for 48 hours or until PCI)

If PTT < 1x control: re-bolus 60 U/kg (max 4000 U) and


increase infusion by 2 U/kg/hr
PTT 1 to 1.5x control: increase infusion by 2 U/kg/hr
PTT 1.5 to 2x control (approx 50-70 sec): no change
(therapeutic range)
PTT 2 to 3x control: decrease infusion rate by 2 U/kg/hr
PTT > 3x control: stop infusion, recheck PTT in 1 hour,
follow algorithm based on repeat PTT

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