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    Transplantation

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    Rahmah Shah Bahai
    The most important complication and cause of death for organ transplant recipients is infection. Graft prognosis is directly related to the donor, with kidneys from living donors having higher survival rates of 95% at 1 year and 76% at 5 years compared to 89% and 61% from cadaveric donors. Major causes of morbidity after transplantation include hypertension, hyperlipidemia, cardiovascular disease, diabetes, osteoporosis, and malignant neoplasms. Recipients from living donors have lower mortality rates than those from cadaveric donors, with survival rates of 98% at 1 year and 91% at 5 years for living donors versus 95% and 81% for cadaveric.

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    Transplantation

    Uploaded by

    Rahmah Shah Bahai
    42 views1 page
    The most important complication and cause of death for organ transplant recipients is infection. Graft prognosis is directly related to the donor, with kidneys from living donors having higher survival rates of 95% at 1 year and 76% at 5 years compared to 89% and 61% from cadaveric donors. Major causes of morbidity after transplantation include hypertension, hyperlipidemia, cardiovascular disease, diabetes, osteoporosis, and malignant neoplasms. Recipients from living donors have lower mortality rates than those from cadaveric donors, with survival rates of 98% at 1 year and 91% at 5 years for living donors versus 95% and 81% for cadaveric.

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    Transplantation

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    The most important complication and cause of death for organ transplant recipients is infection. Graft prognosis is directly related to the donor, with kidneys from living donors having higher survival rates of 95% at 1 year and 76% at 5 years compared to 89% and 61% from cadaveric donors. Major causes of morbidity after transplantation include hypertension, hyperlipidemia, cardiovascular disease, diabetes, osteoporosis, and malignant neoplasms. Recipients from living donors have lower mortality rates than those from cadaveric donors, with survival rates of 98% at 1 year and 91% at 5 years for living donors versus 95% and 81% for cadaveric.

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    42 views1 page

    Transplantation

    Uploaded by

    Rahmah Shah Bahai
    The most important complication and cause of death for organ transplant recipients is infection. Graft prognosis is directly related to the donor, with kidneys from living donors having higher survival rates of 95% at 1 year and 76% at 5 years compared to 89% and 61% from cadaveric donors. Major causes of morbidity after transplantation include hypertension, hyperlipidemia, cardiovascular disease, diabetes, osteoporosis, and malignant neoplasms. Recipients from living donors have lower mortality rates than those from cadaveric donors, with survival rates of 98% at 1 year and 91% at 5 years for living donors versus 95% and 81% for cadaveric.

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    Transplantation

    1- most important complication and cause of death in organ transplant in recipients is:
    a) Rejection
    b) Immunosupression
    c) Steroid overdose
    d) Infection
    - Most common cause of death in organ transplant recipients is:
    A-Rejection
    B-Infection
    C-Steroid overdose
    D-Immunosupression

    Posttransplantation Morbidity and Mortality


    Graft prognosis
    Graft prognosis is directly related to the source of the donor kidney: recipients of cadaveric kidneys
    generally have more episodes of rejection and lower graft survival rates. The graft survival rate for
    kidneys from living donors is approximately 95% at 1 year and 76% at 5 years, whereas the graft
    survival rate for kidneys from cadaveric donors is 89% at 1 year and 61% at 5 years.
    Morbidity
    In addition to complications of transplantation such as infection and graft failure, the major causes
    of morbidity after renal transplantation are hypertension (occurring 75-85% of all renal transplant
    recipients), hyperlipidemia (60%), cardiovascular disease (15.8-23%a 10-fold increase over the
    general population), diabetes mellitus (16.9-19.9%), osteoporosis (60%), malignant neoplasm
    (14%).
    Cardiovascular disease is increased 10-fold compared with the general population, and the rate of
    malignancies appears to be related to the degree of immunosuppression. Diabetes is more likely to
    be present prior to transplantation, and new-onset diabetes is related to corticosteroid use after
    transplantation.
    Mortality
    Predictably, recipients from living related donors have lower mortality rates than recipients from
    cadaveric donors. This is likely related to fewer rejection episodes and thus lower
    immunosuppression requirements. The survival rate of patients after transplantation from a living
    donor is 98% at 1 year and 91% at 5 years; the survival rate after cadaveric donation is 95% at 1
    year and 81% at 5 years. Common causes include coronary artery disease (30.4%), sepsis (27.1%),
    neoplasm (13%), and stroke (8%). During the first year posttransplantation, most deaths are
    due to infectious causes. Long-term mortality rates are more closely related to the development of
    coronary artery disease.

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