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    Fine Needle Aspiration Cytology (Biopsy)

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    delviastri_widyana
    Fine needle aspiration cytology involves using thin needles to aspirate cells or tissue fragments from suspicious masses or abnormalities detected by imaging. It is a relatively non-invasive procedure compared to surgical biopsy and allows for early diagnosis. Samples are smeared and examined under a microscope to analyze cellular characteristics and make a diagnosis. Potential complications are rare and minor. Fine needle aspiration cytology is an accurate, fast, and less painful alternative to surgical biopsy.

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    Fine Needle Aspiration Cytology (Biopsy)

    Uploaded by

    delviastri_widyana
    46 views35 pages
    Fine needle aspiration cytology involves using thin needles to aspirate cells or tissue fragments from suspicious masses or abnormalities detected by imaging. It is a relatively non-invasive procedure compared to surgical biopsy and allows for early diagnosis. Samples are smeared and examined under a microscope to analyze cellular characteristics and make a diagnosis. Potential complications are rare and minor. Fine needle aspiration cytology is an accurate, fast, and less painful alternative to surgical biopsy.

    Original Description:

    FNAC PDL

    Original Title

    FNAC PDL

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    Fine needle aspiration cytology involves using thin needles to aspirate cells or tissue fragments from suspicious masses or abnormalities detected by imaging. It is a relatively non-invasive procedure compared to surgical biopsy and allows for early diagnosis. Samples are smeared and examined under a microscope to analyze cellular characteristics and make a diagnosis. Potential complications are rare and minor. Fine needle aspiration cytology is an accurate, fast, and less painful alternative to surgical biopsy.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    46 views35 pages

    Fine Needle Aspiration Cytology (Biopsy)

    Uploaded by

    delviastri_widyana
    Fine needle aspiration cytology involves using thin needles to aspirate cells or tissue fragments from suspicious masses or abnormalities detected by imaging. It is a relatively non-invasive procedure compared to surgical biopsy and allows for early diagnosis. Samples are smeared and examined under a microscope to analyze cellular characteristics and make a diagnosis. Potential complications are rare and minor. Fine needle aspiration cytology is an accurate, fast, and less painful alternative to surgical biopsy.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    of 35

    Fine Needle

    Aspiration Cytology
    (Biopsy)

    FNAC - definition
    Aspiration

    of cells/ tissue fragments using fine


    needles ( 22 , 23, 25 G) ; external diameter
    0.6 to 1.0 mm
    1.5 inches long needle ( radiologists use
    longer needles)
    Diagnostic materials in the needle and not in
    the syringe even in cystic lesions

    Fine needle aspiration biopsies are often


    performed when a suspicious mass is found, for
    example a breast lump/mass or enlarged lymph
    node, or if an abnormality is detected on an
    imaging test such as x-ray, ultrasound or
    mammography.

    Fine needle aspiration is a relatively noninvasive, less painful and quicker method when
    compared to other methods of tissue sampling
    such as surgical biopsy.

    A cyst aspiration can also be achieved with a


    FNA, where the fluid is drained from a cyst with
    no need for analysis.

    Who should do FNA?


    Clinicians
    Cytotechnologists
    Radiologists
    Pathologists

    ne who examines the patients , does the asp


    es the smears, interprets the cytology
    best one to do FNA PATHOLOGIST

    Current status
    Palpable

    lesions
    Outpatients , in- patients
    Thyroid , breast, lymph nodes,
    salivary glands , soft tissue lumps...
    Lung, intra-abdominal and
    retroperitoneal by radiologic imaging
    : CT, ultrasound, flouroscopy

    Complications

    Needle trauma
    granulation tissue

    formation
    granuloma
    formation
    Sarcoma like
    changes
    Needle linear tract
    haemorrhage
    tissue necrosis

    Needle track
    seeding - testicular
    tm, chondrosar
    Hematoma
    Pain
    Pneumothorax???

    ADVANTAGES
    Fast

    - early diagnosis
    Less pain, less trauma
    No anaesthesia
    Acceptable by patients and doctors
    Accurate

    How to interpret?
    Aspiration

    materials eg colloid,
    blood, mucus?
    Cellular yield vs acellular yield
    Smear pattern - 3 dimensional balls
    vs flat monolayered sheet os cells
    Cohesiveness vs discreet cells
    Cell morphometry

    Adjunct tools
    Cell

    blocks
    Histochemistry
    Immunohistochemistry
    Electron microscopy
    Flow cytometry
    Immuno electron microscopy
    Molecular pathology -In situ
    hybridization, PCR etc

    Adjunct tools
    IHC
    cytology

    Histo - thyroid

    Cell block

    45 yr old woman with


    lytic bone lesion

    Histo -bone

    20

    21

    29

    Maneuver The Target

    30

    Cytology vs Histology

    apillary carcinoma of thyroid - follicular varian

    Cytology vs Histology - 2

    Granular Cell Myoblastoma

    Lumbar puncture
    Aspiration of liver cyst

    Iliac crest puncture of bone marrow

    Terima Kasih

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