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The Cell Cycle and Cancer Instructions

This document provides instructions for a virtual lab simulation on the cell cycle and cancer. The simulation involves examining tissue samples under a microscope to identify and count cells in different stages of the cell cycle, including mitosis and interphase. Students are asked to examine both normal and cancerous tissue samples of the lung, stomach, and ovary, recording cell counts in a data table. They then calculate the average mitotic index and percentage of cells at rest for normal and cancerous tissues from the data. Finally, students answer questions related to differences observed between normal and cancer tissues.

Uploaded by

Taylor Fay
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© © All Rights Reserved
Available Formats
Download as DOC, PDF, TXT or read online on Scribd
51 views

The Cell Cycle and Cancer Instructions

This document provides instructions for a virtual lab simulation on the cell cycle and cancer. The simulation involves examining tissue samples under a microscope to identify and count cells in different stages of the cell cycle, including mitosis and interphase. Students are asked to examine both normal and cancerous tissue samples of the lung, stomach, and ovary, recording cell counts in a data table. They then calculate the average mitotic index and percentage of cells at rest for normal and cancerous tissues from the data. Finally, students answer questions related to differences observed between normal and cancer tissues.

Uploaded by

Taylor Fay
Copyright
© © All Rights Reserved
Available Formats
Download as DOC, PDF, TXT or read online on Scribd
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Virtual Lab: The Cell Cycle and Cancer

Instructions
1. Open the virtual lab: The Cell Cycle and Cancer
2. The lab simulation will be on the right side of the screen, and the Question
column will be on the left side.
3. Read all of the background information and instructions in the Question
column.
4. Click the Information button in the bottom right corner of the lab simulation.
Read all of the background information.
5. Watch the video on Mitosis by clicking on the monitor in the lab simulation.
6. Click on the microscope in the lab simulation to examine the different stages of
mitosis as they appear in different tissue samples. Three types of tissue are
available for examination: lung, stomach, and ovary. Samples of normal tissue
and cancerous tissue are included. Examine both normal and cancerous tissue for
each tissue type. Follow the instructions to label each stage of the cell cycle, and
then check your answers by clicking check. Record the number of cells in each
stage of the cell cycle in the Data Table. You must examine two different views of
each tissue type and condition click reset to view alternate samples of each
tissue type until you have recorded the number of cells in each stage of the cell
cycle for 2 different samples of each tissue.
7. Calculate the average Mitotic Index (% cells dividing) and average % cells at rest
for normal tissues. Record these numbers in the Data Table.
To calculate the average % cells at rest in normal tissue:
1. (#cells in Interphase in Sample 1 + #cells in Interphase in sample 2)/2 =
avg. # cells at rest.
2. (avg. # cells at rest/total #cells) X 100 = average % cells at rest
To calculate the Mitotic Index - average % cells dividing - in normal tissue:
1. (#cells in mitosis in Sample 1 + #cells in mitosis in Sample 2)/2 = avg.
#cells dividing
2. (avg. # cells dividing/total # cells) X 100 = average % cells dividing

7. Do the same calculations for cancerous tissue to complete the Data Table on the
worksheet.
8. Answer questions 1 - 5 on the Cell Cycle and Cancer Worksheet.

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