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    Drug Name

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    Sarah Agudo Fernandez
    Drug Name: Celocoxib (Celebrex) It is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve signs and symptoms of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and other conditions. It works by inhibiting cyclooxygenase-2 (COX-2) to reduce inflammation. It is contraindicated in patients with hypersensitivity, severe hepatic impairment, or in the third trimester of pregnancy due to potential adverse reactions like gastrointestinal issues, edema, rash, and liver toxicity. Nursing considerations include monitoring for signs of bleeding, fluid retention, cardiovascular and liver issues when using this drug.

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    Drug Name

    Uploaded by

    Sarah Agudo Fernandez
    39 views2 pages
    Drug Name: Celocoxib (Celebrex) It is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve signs and symptoms of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and other conditions. It works by inhibiting cyclooxygenase-2 (COX-2) to reduce inflammation. It is contraindicated in patients with hypersensitivity, severe hepatic impairment, or in the third trimester of pregnancy due to potential adverse reactions like gastrointestinal issues, edema, rash, and liver toxicity. Nursing considerations include monitoring for signs of bleeding, fluid retention, cardiovascular and liver issues when using this drug.

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    Drug Name: Celocoxib (Celebrex) It is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve signs and symptoms of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and other conditions. It works by inhibiting cyclooxygenase-2 (COX-2) to reduce inflammation. It is contraindicated in patients with hypersensitivity, severe hepatic impairment, or in the third trimester of pregnancy due to potential adverse reactions like gastrointestinal issues, edema, rash, and liver toxicity. Nursing considerations include monitoring for signs of bleeding, fluid retention, cardiovascular and liver issues when using this drug.

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    Download as DOCX, PDF, TXT or read online from Scribd
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    39 views2 pages

    Drug Name

    Uploaded by

    Sarah Agudo Fernandez
    Drug Name: Celocoxib (Celebrex) It is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve signs and symptoms of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and other conditions. It works by inhibiting cyclooxygenase-2 (COX-2) to reduce inflammation. It is contraindicated in patients with hypersensitivity, severe hepatic impairment, or in the third trimester of pregnancy due to potential adverse reactions like gastrointestinal issues, edema, rash, and liver toxicity. Nursing considerations include monitoring for signs of bleeding, fluid retention, cardiovascular and liver issues when using this drug.

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    Drug Name Generic Name: Celocoxib Brand Name: Celebrex Stock dose: 100 or 200mg/ tab

    Classific ation NSAID

    Action Thought to inhibit prostaglandi n synthesis, impeding cyclooxygen ase- (COX2) to produce antiinflammator y, analgesic, and antipyretic effect.

    Indication To relieve signs and symptoms of osteoarthritis To relieve signs and symptoms of rheumatoid arthritis To relieve signs and symptoms of ankylosing spondylitis Adjunctive treatment for adenomatous polyposis to reduce the number of adematous colorectal polyps Acute pain and primary dysmenorrheal

    Contraindication Contraindicated in patients hypersensitivity to drug, aspirin, sulfonamides, and other NSAIDs Contraindicated in those with severe hepatic impairment and in the treatment of perioperative pain after coronary artery bypass graft surgery Avoid use in the third trimester of pregnancy

    Adverse Reaction CNS: dizziness, headache, insomnia CV: peripheral edema EENT: pharyngitis, rhinitis, sinusitis GI: abdominal pain, diarrhea, nausea, flatulence, dyspepsia Metabolic: nyperchloremia Musculoskeletal: back pain Respiratory: URTI Skin: rash, toxic eptdermal necrolysis, stevensJohnson syndrome, erythema multiforme, exfoliatve dermatitis Other: a ccidental injury

    Nursing Considerations Ask patients allergic to or with a history of anaphylactic reaction to sulfonamides, aspirin, or other NSAIDs may be allergic to this drug Patient with history of ulcers or GI bleeding is at high risk for GI bleeding while taking NSAIDs, such as celecoxib. Other risk factors for GI bleeding include treatment with corticosteroids or anticoagulants, longer duration of NSAID treatment, smoking, alcoholism, older age and poor overall health NSAIDs may increase the risk of serious thrombotic events, MI, or stroke. The risk mat be greater with longer use or in patients with CV disease or risk factors for CV disease Although drug may be use with low aspirin dosages the combination may increase risk for GI bleeding Watch for signs and symptoms of overt and occult bleeding NSAIDs such as celecoxib can cause fluid retention, monitor patients with hypertension, edema or heart failure Assess patients with CV risk factor before therapy Drugs may be hepatotoxic, watch for sign and symptom of liver toxicity Before starting drug therapy, rehydrate dehydrated patient Drugs can be given without regard to meals, but food may decrease GI upset Dont confuse celecoxib with cerebyx or celexa Tell patient to report history of allergic reactions to sulfonamides, aspirin or other NSAIDs before starting therapy Instruct patient to promptly report signs of GI bleeding such as blood in vomit, urine or stool; or black, tarry stool Advise patient to immediately report ras, unexplained weight gain or swelling

    Tell woman to notify prescriber if she becomes pregnant or is planning to become pregnant during drug therapy Instruct patient to take drug with meal if stomach upset occurs Teach patients that all NSAIDs including celecoxib, may harm the liver. Advise patient to stop therapy and notify prescriber immediately if he experiences signs and symptoms of liver toxicity, including nausea, fatigue, lethargy, itching, yellowing of skin or eyes, right upper quadrant tenderness, and flulike syndrome Inform patient it may take several days before he feels consistent pain relief Advise patient that using OTC NSAIDs with celecoxib may increase the risk of GI toxicity

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